Terkko Navigator / Väänänen, H.K.

Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells

Role of fibroblast growth factor receptors (FGFR) and FGFR like-1 (FGFRL1) in mesenchymal stromal cell differentiation to osteoblasts and adipocytes

The effects of acute hyperinsulinemia on bone metabolism

Novel perspectives on the transcytotic route in osteoclasts

Serum osteocalcin is not associated with glucose but is inversely associated with leptin across generations of nondiabetic women

Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells

Transient 100 nM dexamethasone treatment reduces inter- and intraindividual variations in osteoblastic differentiation of bone marrow-derived human mesenchymal stem cells

Urinary osteocalcin and serum pro-C-type natriuretic peptide predict linear catch-up growth in infants

The effect of oral glucose tolerance test on serum osteocalcin and bone turnover markers in young adults

Receptor tyrosine kinase inhibition causes simultaneous bone loss and excess bone formation within growing bone in rats

The critical role of IL-34 in osteoclastogenesis

A rationale for osteoclast selectivity of inhibiting the lysosomal V-ATPase a3 isoform

Can elevated serum TRACP-5b levels predict stress fractures? A cohort study

Degradation of hydroxyapatite in vivo and in vitro requires osteoclastic sodium-bicarbonate co-transporter NBCn1

Bone turnover markers and prediction of fracture: a prospective follow-up study of 1040 elderly women for a mean of 9 years

Overexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumors

Evidence for the role of osteocytes in the initiation of targeted remodeling

Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading

FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer

Effect of impact exercise on bone metabolism

Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro

Clinical performance of six different serum tartrate-resistant acid phosphatase assays for monitoring alendronate treatment

Improved methods for testing antiresorptive compounds in human osteoclast cultures

Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules

Serial assessment of serum bone metabolism markers identifies women with the highest rate of bone loss and osteoporosis risk

Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells

Osteoclast lineage and function

Recombinant VSV G proteins reveal a novel raft-dependent endocytic pathway in resorbing osteoclasts

FGF-8 is involved in bone metastasis of prostate cancer

Overexpression of human hydroxysteroid (17beta) dehydrogenase 2 induces disturbance in skeletal development in young male mice

Sequence and TLR9 independent increase of TRACP expression by antisense DNA and siRNA molecules

RNA interference tolerates 2'-fluoro modifications at the Argonaute2 cleavage site

Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro

Membrane-bound carbonic anhydrases in osteoclasts

Monocyte-macrophage system as a target for estrogen and selective estrogen receptor modulators

Tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of bone resorption

Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women

Serum TRACP 5b and ICTP as markers of bone metastases in breast cancer

Effects of proteolysis and reduction on phosphatase and ROS-generating activity of human tartrate-resistant acid phosphatase

Bone marrow cell differentiation induced by mechanically damaged osteocytes in 3D gel-embedded culture

Pharmacological sequestration of intracellular cholesterol in late endosomes disrupts ruffled border formation in osteoclasts

Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8

Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover

Cystatin B as an intracellular modulator of bone resorption

Urinary osteocalcin is a useful marker for monitoring the effect of alendronate therapy

Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption

Mesenchymal stem cells

Serum tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of skeletal changes in prostate cancer

Isolated primary osteocytes express functional gap junctions in vitro

Inhibition of the osteoclast V-ATPase by small interfering RNAs