Table of Contents

Epidemiology.
Genetics and molecular biology of renal stones.
Physicochemical aspects of uro-crystallization and stone formation.
The Possible roles of inhibitors promoters and macromolecules in the formation of calcium kidney stones.
Renal cellular dysfunction damage and the formation of kidney stones.
Interaction of stone components with cells and tissues.
Randall's plaques.
Dietary factors.
Obesity metabolic syndrome and stones.
Stone disease in animals.
Pathogenesis of stones: summary of current concepts.
Calcium metabolism and hypercalciuria.
Vitamin D metabolism and stones.
Urinary citrate and citrate metabolism.
Uric acid metabolism and uric acid stones.
Oxalate metabolism and the primary hyperoxalurias.
Cystinuria and cystine stones.
Urinary infection and struvite stones.
Drug-induced renal stones.
Endemic bladder stones.
Economic implications of medical and surgical management.
What are shock waves.
Extracorporeal shock wave lithotriptors.
Biological effects produced by high energy shock waves.
Intracorporeal nonlaser lithotripsy.
Laser lithotripsy physics.
Alternative laser energy sources: clinical implications.
Imaging for stones.
Urinary stone analysis.
Risk indices.
Blood and urinary tests in stone formers.
Crystallization and other studies.
Experimental models for investigation of stone disease.
Clinical trials in stone disease.
Epidemiology of pediatric urolithiasis.
Metabolic stone disease in children.
The Role of minimally invasive techniques.
Indications for surgical removal including asymptomatic stones.
Renal stones.
Extracorporeal shock wave lithotripsy for ureteral stones.
Percutaneous nephrolithotomy.
Ureteroscopy for ureteric stones.
Indications for and technique of retrograde intrarenal surgery for renal stones.
Urolithiasis in pregnancy.
Surgical management of urolithiasis in transplanted kidneys.
Stents and stenting.
Flexible ureterorenoscopy: tips and tricks.
Training implications for stone management.
Open surgery to remove stones: when and how.
Autotransplantation and ureteric replacement: in whom and how.
Liver and renal transplantation in primary hyperoxaluria.
Chemolytic treatment of patients with urinary tract stones.
Establishment and management of a stone clinic.
Medical expulsive therapy.
Metabolic investigations: when and in whom.
Medical management of idiopathic calcium stone disease.
Medical management: uric acid and cystine stones.
Medical management of struvite stones.
Dietary assessment and advice.
Stone management in the presence of morbid obesity. Urinary stone disease constitutes more than a quarter of urologists' workload in the Western countries and is more than half in the Middle-East and Central Asian countries. The surgical management of stone disease has changed considerably in the last five years and our understanding of mechanism of stone disease has improved with some old concepts discarded and newer theories gaining ground. Covering the entire spectrum of urinary stone disease and with contributions of more than fifty internationally recognised experts, this exhaustive and complex reference work will be invaluable to all urol.