Table of Contents

9781847355645 _Front Cover.pdf; 9781847355645 _Content.pdf; Update on Polymers for Ocular Drug Delivery; Dedication and Acknowledgements; Contents; Preface; 1 Introduction: Overview of Ocular Drug Delivery; 1.1 Drug Delivery and Polymer Science; 1.2 Ocular Drug Delivery; 1.2.1 Anatomy and Physiology of the Eye; 1.2.2 Pharmacokinetics of Drugs Delivered through the Ocular Route; References; 2 Conventional Ocular Drug Delivery; 2.1 Introduction; 2.2 Eye Drops; 2.2.1 Aqueous Solutions; 2.2.2 Ophthalmic Suspensions; 2.3 Semisolids; 2.4 Summary and Conclusion; References. The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action. Poor bioavailability of drugs from ocular dosage forms is mainly due to the precorneal loss factors which include tear dynamics, non-productive absorption, transient residence time in the cul-de-sac, and the relative impermeability of the corneal epithelial membrane. Due to these physiological.