Table of Contents

Section I : Hot Topics in Vascular Biology.
1. Pericytes : Adaptable Vascular Progenitors / Gareth D. Hyde and Ann E. Canfield.
2. Benefits and Risks of Manipulating the HIF Hydroxylase Pathway in Ischemic Heart Disease / Tammie Bishop and Peter J. Ratcliffe.
3. Cytoprotective Mechanisms in the Vasculature / Justin C. Mason.
4. Notch Signaling in Vascular Development / Shalini Jadeja and Marcus Fruttiger.
Section II : Novel Molecular Mediators Regulating Cardiovascular System.
5. The Therapeutic Potential of Dimethylarginine Dimethylaminohydrolase-Mediated Regulation of Nitric Oxide Synthesis / James Leiper, F. Arrigoni, and B. Ahmetaj.
6. Potassium Channels Regulating the Electrical Activity of the Heart / Andrew Tinker and Stephen C. Harmer.
7. Free Radicals, Oxidative Stress, and Cardiovascular Disease / K. Richard Bruckdorfer.
Section III : Clinical Aspects of Cardiovascular Disease.
8. The Takotsubo (Broken Heart Syndrome) / Lawrence S. Cohen.
9. Lymphatic Vessels in Health and Disease / Elisabetta Weber, Francesca Sozio, Erica Gabbrielli, and Antonella Rossi.
10. Importance of Subtype Selectivity for Endothelin Receptor Antagonists in the Human Vasculature / Janet J. Maguire and Anthony P. Davenport.
11. Non-Pharmacological Treatment of Peripheral Vascular Disease / Janice Tsui and George Hamilton.
12. Surgical Approaches to Abdominal Aortic Aneurysm Repair / Matt Thompson, Peter Holt, Rob Hinchliffe, and Ian Loftus.
Section IV : Clinical and Translational Aspects of Pulmonary Vascular Disease.
13. Understanding the Pathobiology of Pulmonary Vascular Disease / Kristin B. Highland.
14. Inflammation in Pulmonary Arterial Hypertension / Frédéric Perros, Sylvia Cohen-Kaminsky, Peter Dorfmüller, Alice Huertas, Marie-Camille Chaumais, David Montani, and Marc Humbert.
15. Endothelin Receptor Antagonists in Cardiovascular Medicine : Challenges and Opportunities / Matthias Barton.