Terkko Navigator / Structure

Tightening the Crosslinking Distance Restraints for Better Resolution of Protein Structure and Dynamics

A Single-Molecule Surface-Based Platform to Detect the Assembly and Function of the Human RNA Polymerase II Transcription Machinery

D-Serine Potently Drives Ligand-Binding Domain Closure in the Ionotropic Glutamate Receptor GluD2

Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED

Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1

The Binding of Palonosetron and Other Antiemetic Drugs to the Serotonin 5-HT3 Receptor

Crystal Structure of MLL2 Complex Guides the Identification of a Methylation Site on P53 Catalyzed by KMT2 Family Methyltransferases

Structure of the Human Respiratory Syncytial Virus M2-1 Protein in Complex with a Short Positive-Sense Gene-End RNA

Structure of the Regulatory Cytosolic Domain of a Eukaryotic Potassium-Chloride Cotransporter

The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain

MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases

Performance and Its Limits in Rigid Body Protein-Protein Docking

Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants

Cryoelectron Tomography Reveals Nanoscale Organization of the Cytoskeleton and Its Relation to Microtubule Curvature Inside Cells

Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide

Protein Motional Details Revealed by Complementary Structural Biology Techniques

Combining Information from Crosslinks and Monolinks in the Modeling of Protein Structures

FARFAR2: Improved De Novo Rosetta Prediction of Complex Global RNA Folds

Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors

Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase

Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations

Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling

A Conserved Proline Hinge Mediates Helix Dynamics and Activation of Rhodopsin

How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone

Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function

Structural and Functional Analyses of the FAM46C/Plk4 Complex

Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions

GemSpot: A Pipeline for Robust Modeling of Ligands into Cryo-EM Maps

Acquired Functional Capsid Structures in Metazoan Totivirus-like dsRNA Virus

Organizational Principles of the NuMA-Dynein Interaction Interface and Implications for Mitotic Spindle Functions

F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening

Activation of Phospholipase C β by Gβγ and Gαq Involves C-Terminal Rearrangement to Release Autoinhibition

Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins

Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase

Structural and Functional Studies of a Klebsiella Phage Capsule Depolymerase Tailspike: Mechanistic Insights into Capsular Degradation

Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair

Computational Modeling of Protein Stability: Quantitative Analysis Reveals Solutions to Pervasive Problems

Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition

Identification of a Structural Determinant for Selective Targeting of HDMX

Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment

Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins

Structural Basis for the High-Affinity Interaction between CASK and Mint1

D-loop Dynamics and Near-Atomic-Resolution Cryo-EM Structure of Phalloidin-Bound F-Actin

Distinct Allosteric Networks Underlie Mechanistic Speciation of ABC Transporters

Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa

Directed Computational Evolution of Quorum-Quenching Lactonases from the Amidohydrolase Superfamily

Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study

Mechanism of CcdA-Mediated Rejuvenation of DNA Gyrase

High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines