Terkko Navigator / Science Translational Medicine

Erratum for the Research Article: "Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine" by L. Gao, L. Wang, Y. Wei, P. Krishnamurthy, G. P. Walcott, P. Menasche, J. Zhang

Bispecific CAR T cells have a dual grasp on tumors

Early stage EGFR-mutated lung cancer gets a targeted treatment

Encapsulating a leukemia vaccine

Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models

A probiotic yeast-based immunotherapy against Clostridioides difficile infection

Nonhuman primates exposed to Zika virus in utero are not protected against reinfection at 1 year postpartum

Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice

A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease

Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity

Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans

Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation

Editorial expression of concern

Achieving healthy human longevity: A global grand challenge

ANXA11 mutations in ALS cause dysregulation of calcium homeostasis and stress granule dynamics

Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3

Down-regulation of Beclin1 promotes direct cardiac reprogramming

Antibiotics make a double play

Lymph nodes: The cradle for antitumor immunity

Treating diabetes with electromagnetic fields

Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma

Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti-PD-1 for patients with anti-PD-1-refractory tumors

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration

Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment

Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip

Good sleep for healthy kidneys

Getting to the heart of bone loss

Weekly insulin dosing: Are we there yet?

Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide

Immunocytokines are a promising immunotherapeutic approach against glioblastoma

Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study

Potential impact of tuberculosis vaccines in China, South Africa, and India

ICOSL+ plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist

Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients

Stimulating brain drug delivery

Outsourcing glucose management to AI

Single-cell transcriptomic architecture of endothelial cells

Paenibacillus infection with frequent viral coinfection contributes to postinfectious hydrocephalus in Ugandan infants

Global approaches to genomic medicine implementation

A{beta}-accelerated neurodegeneration caused by Alzheimers-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice

Exosomes derived from V{delta}2-T cells control Epstein-Barr virus-associated tumors and induce T cell antitumor immunity

Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy

Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis

MIS-Cing pieces of the puzzle

Signal autonomy: Skeletal muscle in diabetes

Uncovering metabolic states in cytotoxic T cells, one cell at a time