Terkko Navigator / Science Translational Medicine

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimers disease risk

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

Disrupted hippocampal growth hormone secretagogue receptor 1{alpha} interaction with dopamine receptor D1 plays a role in Alzheimer's disease

Evaluating strategies to improve rotavirus vaccine impact during the second year of life in Malawi

MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21

Broadening vaccine strategies to induce HIV broadly neutralizing antibodies

Better living through your gut microbes

Immune-orthogonal orthologs: The solution for genome editing?

Intranasal micro-optical coherence tomography imaging for cystic fibrosis studies

Lysozyme elicits pain during nerve injury by neuronal Toll-like receptor 4 activation and has therapeutic potential in neuropathic pain

Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells

Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model

Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer

Resolving deep vein thrombosis

Secreted frizzled-related protein 1 frazzles the brain in Alzheimers disease

Aging is just a state of marrow

Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice

Snake fang-inspired stamping patch for transdermal delivery of liquid formulations

Cancer likes it saturated

Early life stress: Its all in the timing

A new approach to local drug delivery bubbling under the surface

Therapeutically relevant engraftment of a CRISPR-Cas9-edited HSC-enriched population with HbF reactivation in nonhuman primates

The androgen receptor regulates a druggable translational regulon in advanced prostate cancer

Conformable bioelectronic interfaces: Mapping the road ahead

Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain

Fluid assessment in dialysis patients by point-of-care magnetic relaxometry

More blurred lines with innate lymphoid cells

How to save a life

Bedazzled biomaterials: Crystallized drugs prevent implant fibrosis

AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239 challenges

The 1918 influenza pandemic: 100 years of questions answered and unanswered

The gut microbiota influences skeletal muscle mass and function in mice

Multifunctional scaffolds for facile implantation, spontaneous fixation, and accelerated long bone regeneration in rodents

Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia"

Response to Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia"

Diverse compositions and functions of chromatin remodeling machines in cancer

Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity

A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge

Calpain 9 as a therapeutic target in TGF{beta}-induced mesenchymal transition and fibrosis

Innate lymphoid cells pack on the pounds

A mitochondrial Pac-man drug to tackle aging

A probiotic for treating cancer

A multimodality test to guide the management of patients with a pancreatic cyst

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Autoimmune receptor encephalitis in mice induced by active immunization with conformationally stabilized holoreceptors

Translational impact of NIH-funded nonhuman primate research in transplantation

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

From mini-brains to neural networks

A primate resource for autism research

Gut microbes prevent marathoners from pooping out