Terkko Navigator / Saharinen, P(ipsa)*

Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell surface expression

Lysophosphatidylcholine in phospholipase A₂-modified LDL triggers secretion of angiopoietin 2

Characterization of <em>ANGPT2</em> mutations associated with primary lymphedema

Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <em>Kras</em>-Mutant Lung Cancers

Targetingβ1-integrin inhibits vascular leakage in endotoxemia

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 andβ1-integrin activation

SnapShot: Angiopoietins and Their Functions

Therapeutic targeting of the angiopoietin-TIE pathway

Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization

Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems

Novel Angiogenesis Markers as Long-Term Prognostic Factors in Patients With Renal Cell Cancer

Tie1 controls angiopoietin function in vascular remodeling and inflammation

Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation

Critical requirement of VEGF-C in transition to fetal erythropoiesis

Simvastatin pretreatment reduces caspase-9 and RIPK1 protein activity in rat cardiac allograft ischemia-reperfusion

Association of Angiopoietin-2 and Ki-67 Expression with Vascular Density and Sunitinib Response in Metastatic Renal Cell Carcinoma

VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption

Blocking integrin inactivation as an anti-angiogenic therapy

Endothelial destabilization by angiopoietin-2 via integrinβ1 activation

The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis

VEGF-C and aortic cardiomyocytes guide coronary artery stem development

The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel

Angiopoietin-2 inhibition prevents transplant ischemia-reperfusion injury and chronic rejection in rat cardiac allografts

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy

Receptor tyrosine kinase-mediated angiogenesis

Donor simvastatin treatment prevents ischemia-reperfusion and acute kidney injury by preserving microvascular barrier function

Angiopoietin signaling in the vasculature

Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis

Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses

Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis

The yin, the yang, and the angiopoietin-1

VEGF and angiopoietin signaling in tumor angiogenesis and metastasis

Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

How do angiopoietins Tie in with vascular endothelial growth factors?

Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity

Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report

Recessive primary congenital lymphoedema caused by a VEGFR3 mutation

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitro

Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state

Signaling and functions of angiopoietin-1 in vascular protection

Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2

The Janus kinases (Jaks)

Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation

Molecular regulation of lymphangiogenesis

Double target for tumor mass destruction

Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain

The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction

Effects of hyperactive Janus kinase 2 signaling in mammary epithelial cells