Table of Contents

In vitro characterization of small-molecule kinase inhibitors.
Screening for kinase inhibitors: from biochemical to cellular assays.
Dissecting phosphorylation networks: the use of analogue-sensitive kinases and more specific kinase inhibitors as tools.
Rational drug design of kinase inhibitors for signal transduction therapy.
Kinaes inhibitors in signal transduction therapy.
Design principles of deep pocket-targeting protein kinase inhibitors.
From discovery to clinic: aurora kinase inhibitors as novel treatments for cancer.
Discovery and design of protein kinase inhibitors: targeting the cell cycle in oncology.
Medicinal chemistry approaches for the inhibition of the p38 MAPK pathway.
Cellular protein kinases as antiviral targets.
Prospects for TB therapeutics targeting mycobacterium tuberculosis phosphosignaling networks.