Table of Contents

Cover.
QUOTES FROM REVIEWS OF PREVIOUS EDITIONS.
TOC$CONTENTS.
PREFACE TO THE FOURTH EDITION.
PREFACE TO THE THIRD EDITION.
PREFACE TO THE SECOND EDITION.
PREFACE TO THE FIRST EDITION.
THE PRINCIPLES OF MOLECULAR VIROLOGY CD.
CH$CHAPTER 1: INTRODUCTION.
VIRUSES ARE DISTINCT FROM LIVING ORGANISMS.
THE HISTORY OF VIROLOGY.
LIVING HOST SYSTEMS.
CELL CULTURE METHODS.
SEROLOGICAL/IMMUNOLOGICAL METHODS.
ULTRASTRUCTURAL STUDIES.
'MOLECULAR BIOLOGY'.
FURTHER READING.
CH$CHAPTER 2: PARTICLES.
THE FUNCTION AND FORMATION OF VIRUS PARTICLES.
CAPSID SYMMETRY AND VIRUS ARCHITECTURE.
ENVELOPED VIRUSES.
COMPLEX VIRUS STRUCTURES.
PROTEIN-NUCLEIC ACID INTERACTIONS AND GENOME PACKAGING.
VIRUS RECEPTORS: RECOGNITION AND BINDING.
OTHER INTERACTIONS OF THE VIRUS CAPSID WITH THE HOST CELL.
SUMMARY.
FURTHER READING.
CH$CHAPTER 3: GENOMES.
THE STRUCTURE AND COMPLEXITY OF VIRUS GENOMES.
MOLECULAR GENETICS.
VIRUS GENETICS.
VIRUS MUTANTS.
SUPPRESSION.
GENETIC INTERACTIONS BETWEEN VIRUSES.
NONGENETIC INTERACTIONS BETWEEN VIRUSES.
'LARGE' DNA GENOMES.
'SMALL' DNA GENOMES.
POSITIVE-STRAND RNA VIRUSES.
NEGATIVE-STRAND RNA VIRUSES.
SEGMENTED AND MULTIPARTITE VIRUS GENOMES.
REVERSE TRANSCRIPTION AND TRANSPOSITION.
EVOLUTION AND EPIDEMIOLOGY.
SUMMARY.
FURTHER READING.
CH$CHAPTER 4: REPLICATION.
OVERVIEW OF VIRUS REPLICATION.
INVESTIGATION OF VIRUS REPLICATION.
THE REPLICATION CYCLE.
SUMMARY.
FURTHER READING.
CH$CHAPTER 5: EXPRESSION.
EXPRESSION OF GENETIC INFORMATION.
CONTROL OF PROKARYOTE GENE EXPRESSION.
CONTROL OF EXPRESSION IN BACTERIOPHAGE l.
CONTROL OF EUKARYOTE GENE EXPRESSION.
TRANSCRIPTIONAL CONTROL OF EXPRESSION.
POSTTRANSCRIPTIONAL CONTROL OF EXPRESSION.
SUMMARY.
FURTHER READING.
CH$CHAPTER 6: INFECTION.
VIRUS INFECTIONS OF PLANTS.
IMMUNE RESPONSES TO VIRUS INFECTIONS IN ANIMALS.
VIRUSES AND APOPTOSIS.
INTERFERONS.
EVASION OF IMMUNE RESPONSES BY VIRUSES.
VIRUS-HOST INTERACTIONS.
THE COURSE OF VIRUS INFECTIONS.
VIRUS VECTORS AND GENE THERAPY.
CHEMOTHERAPY OF VIRUS INFECTIONS.
SUMMARY.
FURTHER READING.
CH$CHAPTER 7: PATHOGENESIS.
MECHANISMS OF CELLULAR INJURY.
VIRUSES AND IMMUNODEFICIENCY.
VIRUS-RELATED DISEASES.
BACTERIOPHAGES AND HUMAN DISEASE.
CELL TRANSFORMATION BY VIRUSES.
VIRUSES AND CANCER.
NEW AND EMERGENT VIRUSES.
ZOONOSES.
BIOTERRORISM.
SUMMARY.
FURTHER READING.
CH$CHAPTER 8: SUBVIRAL AGENTS: GENOMES WITHOUT VIRUSES, VIRUSES WITHOUT GENOMES.
SATELLITES AND VIROIDS.
PRIONS.
SUMMARY.
FURTHER READING.
APPENDIX 1: GLOSSARY AND ABBREVIATIONS.
APPENDIX 2: CLASSIFICATION OF SUBCELLULAR INFECTIOUS AGENTS.
APPENDIX 3: THE HISTORY OF VIROLOGY.
IDX$INDEX.
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