Table of Contents

Introduction to biomolecules.
Introduction to protein structure.
Oxygen-binding proteins : hemoglobin and myoglobin.
Enzymatic reactions.
DNA, RNA, and protein synthesis.
The human genome.
Protein targeting and proteostasis.
Introduction to genetic diseases.
DNA technology.
Biological membranes.
The cytoskeleton.
The extracellular matrix.
Extracellular messengers.
Intracellular messengers.
Plasma proteins.
Defense mechanisms.
Cellular growth control and cancer.
Digestive enzymes.
Introduction to metabolic pathways.
Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation.
Oxygen deficiency and oxygen toxicity.
Carbohydrate metabolism.
The metabolism of fatty acids and triglycerides.
The metabolism of membrane lipids.
Lipid transport.
Amino acid metabolism.
Metabolism of iron and heme.
The metabolism of purines and pyrimidines.
Integration of metabolism. For nearly 30 years, Principles of Medical Biochemistry has integrated medical biochemistry with molecular genetics, cell biology, and genetics to provide complete yet concise coverage that links biochemistry with clinical medicine. The 4th Edition of this award-winning text by Drs. Gerhard Meisenberg and William H. Simmons has been fully updated with new clinical examples, expanded coverage of recent changes in the field, and many new case studies online. A highly visual format helps readers retain complex information, and USMLE-style questions (in print and online) assist with exam preparation.