Table of Contents

Epidemiology of overweight/obesity and cancer risk.
Epidemiology of physical activity and cancer risk.
Energetics and cancer: exploring a road less traveled.
Calorie restriction, exercise, and colon cancer prevention: a mechanistic perspective.
Mechanisms linking obesity to cancer risk.
Mechanisms underlying the effects of physical activity on cancer.
Physical activity, weight control, and cancer prognosis. The World Health Organization estimates that 25 per cent of common cancers can be prevented through regular physical activity and weight control. Common cancers linked to overweight/obesity and a sedentary lifestyle include breast, colon, endometrium, pancreas, renal, esophageal, and several others. There are several plausible mechanisms linking lack of physical activity and increased adiposity to cancer risk, supported by results from animal experiments and human intervention studies.