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Differences in signalling, trafficking and glucoregulatory properties of glucagon-like peptide-1 receptor agonists exendin-4 and lixisenatide

A model to study NMDA receptors in early nervous system development

Biased M1 positive allosteric modulators reveal novel role of phospholipase D in M1-dependent rodent cortical plasticity

Integrating healthcare and research genetic data empowers the discovery of 49 novel developmental disorders

Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes

Selective 40S footprinting reveals that scanning ribosomes remain cap-tethered in human cells

Identification Of Peptides Interfering The LRRK2/PP1 Interaction

A memory of RPS25 loss drives resistance phenotypes

Dis3L2 regulates cellular proliferation through a PI3-Kinase dependent signalling pathway

Extracellular ATP and CD39 activate cAMP-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia

AKT2 deficiency causes sarcopenia and metabolic disorder of skeletal muscle

Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements

DNA hydroxymethylation reveals transcription regulation networks and prognostic signatures in multiple myeloma

Exosomes transmit retroelement RNAs to drive inflammation and immunosuppression in Ewing Sarcoma

In vivo imaging defines vascular interplay in the development of lymphocytic leukemia in zebrafish models

Coding and noncoding somatic mutations in basal cell carcinoma

Modulating Sphingosine-1-Phosphate receptors to improve chemotherapy delivery to Ewing sarcoma

Low dose Cold Atmospheric Plasma induces membrane oxidation, stimulates endocytosis and enhances uptake of nanomaterials in Glioblastoma multiforme cells

Analysis of the FBXO7 promoter reveals overlapping Pax5 and c-Myb binding sites functioning in B cells

Drug Combination Antagonism and Single Agent Dominance Result from Differences in Death Activation Kinetics

Enzyme Catalytic Activity Emulated Within DNA-based Nanodevice

A novel major output target for pheromone-sensitive projection neurons in male moths

Prophage induction mediated by quorum sensing signals alters soil bacterial community structure

HPV can establish productive infection in dysplastic oral mucosa, but HPV status is poorly predicted by histological features and p16 expression

Fiber type diversity in skeletal muscle explored by mass spectrometry-based single fiber proteomics.

Persistent DNA Hyper-methylation Dampens Host Anti-Mycobacterial Immunity

Cryo-electron microscopy structure of a nucleosome-bound SWI/SNF chromatin remodeling complex

Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement

Phytotransferrin endocytosis mediates a direct cell surface-to-chloroplast iron trafficking axis in marine diatoms

Unconventional kinetochore kinases KKT10/19 promote the metaphase to anaphase transition in Trypanosoma brucei

Niche-inspired synthetic matrices for epithelial organoid culture

Muscles Recruited During an Isometric Knee Extension Task is Defined by Proprioceptive Feedback

Assessing exposure effects on gene expression

Compositional and functional differences of the mucosal microbiota along the intestine of healthy individuals

Efficient and robust coding in heterogeneous recurrent networks

Measuring chromosome conformation by fluorescence microscopy

Curling of epithelial monolayers reveals coupling between active bending and tissue tension

Targeting endogenous K-RAS for degradation through the affinity-directed protein missile system

Integrative genomic, transcriptomic, and epigenomic analyses of benign prostatic hyperplasia reveal new options for therapy

Microtubule polymerization state and clathrin-dependent internalization regulate dynamics of cardiac potassium channel

Classification of platelet aggregates by agonist type

Specific decreasing of Na+ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome

Widespread inhibitory responses in the mouse olfactory sensory neurons in vivo

Hippocampal spike-time correlations and place-field overlaps during open field foraging

Junction-skipping regulation in complex disease

Champagne: Whole-genome phylogenomic character matrix method places Myomorpha basal in Rodentia

Idea Paper: Predicting culturability of microbes from population dynamics under field conditions

Geographical distribution of Anopheles stephensi in eastern Ethiopia

Spatiotemporal control of gene expression boundaries using a feedforward loop

A weak link with actin organizes tight junctions to control epithelial permeability