Terkko Navigator / Nature Reviews Cancer

Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours

Mimicking multi-organ drug effects

Alternative tumour-specific antigens

YAP and TAZ: a signalling hub of the tumour microenvironment

Adjusting the focus on γ-secretase inhibition

Of scientists and tweets

Unmasking senescence: context-dependent effects of SASP in cancer

Fibroblasts shape PDAC architecture

Phenotype plasticity as enabler of melanoma progression and therapy resistance

γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer

Trifunctional antibodies unleash NK cells

Ripretinib turns off the switch in GIST

The cancer microbiome

Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

Mapping dysfunction of the bone marrow stroma in leukaemia

Throwing Treg cells off balance

The importance of including diverse populations in cancer genomic and epigenomic studies

Gene-fusion neoantigens stimulate T cells

Glutamine-fuelled OXPHOS — a new target in MCL

Nervous tumours

Context determines which pathway to use for NAD synthesis

Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion

Tertiary lymphoid structures in the era of cancer immunotherapy

Going to extremes: determinants of extraordinary response and survival in patients with cancer

Prophylactic TNF blockade reduces autoimmune toxicity

E-selectin fills two needs for metastasis

The broken cycle: E2F dysfunction in cancer

Better safe than sorry: a potential prophylactic treatment for brain metastasis

Macrophage manipulation

Prioritizing synthetic lethal targets with functional genomics

Platelets with dangerous cargo

Cancer overdiagnosis: a biological challenge and clinical dilemma

Targeting cancer vulnerabilities with high-dose vitamin C

Long path to MYC inhibition approaches clinical trials

Targeting chromatin complexes in fusion protein-driven malignancies

Searching for a diagnosis

Targeting cancer cell metabolism in glioblastoma

Eliminating protective autophagy in KRAS-mutant cancers

What’s driving T cell dysfunction?

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

Overflow disrupts the genome

Stressed out!

Renovation in progress

Extrachromosomal oncogene amplification in tumour pathogenesis and evolution

Host tissue determinants of tumour immunity

States of exhaustion

Diverging inflammasome signals in tumorigenesis and potential targeting

Engineering advanced cancer therapies with synthetic biology

Embedding a positive research culture that fosters innovation

The mechanics of tumour formation