Terkko Navigator / Nature Biotechnology

Publisher Correction: Light-activated genetic therapy to treat blindness enters clinic

Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin

Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells

The missing sex

Biological activity-based modeling identifies antiviral leads against SARS-CoV-2

Mapping innovation trajectories on SARS-CoV-2 and its variants

Variability within rare cell states enables multiple paths toward drug resistance

Could mutations of SARS-CoV-2 suppress diagnostic detection?

Robust decomposition of cell type mixtures in spatial transcriptomics

How large pharma impacts biotechnology startup success

Deep diversification of an AAV capsid protein by machine learning

A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer

Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics

Around the world in a month

Liquid biopsy

Dendritic cell revival

Atalanta pioneers siRNA for neurodegenerative diseases

Diabetes drug on trial for Alzheimer’s

Financing breaks all records in 2020

Trop2 deal heats up antibody–drug conjugate space in cancer

Drug pipeline 4Q20

Human heart-forming organoids recapitulate early heart and foregut development

Quantifying the effect of experimental perturbations at single-cell resolution

Balancing clinical evidence in the context of a pandemic

Publisher Correction: First small-molecule drug targeting RNA gains momentum

Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents

UMI or not UMI, that is the question for scRNA-seq zero-inflation

Cleaning house

Reply to: UMI or not UMI, that is the question for scRNA-seq zero-inflation

Initialization is critical for preserving global data structure in both t-SNE and UMAP

Will Ethiopia be a springboard or a stonewall for GM crops in Africa?

Noncanonical open reading frames encode functional proteins essential for cancer cell survival

Building a high-quality Human Cell Atlas

Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin

Research priorities for COVID-19 sensor technology

inStrain profiles population microdiversity from metagenomic data and sensitively detects shared microbial strains

Assessing single-cell transcriptomic variability through density-preserving data visualization

Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes

Around the world in a month

FDA clears first drug for premature aging disease

Antibody–drug conjugates for cancer score with ROR1

Circular RNA

Thumbs up for cholesterol-slashing siRNA blockbuster

AstraZeneca joins Russia to boost coronavirus vaccine

People

Hunt for improved monoclonals against coronavirus gathers pace

First Rounders: Grace Colón

Left-handed DNA-PAINT for improved super-resolution imaging in the nucleus

Improved metagenome binning and assembly using deep variational autoencoders

A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in wheat