Terkko Navigator / Nature Biotechnology

First Rounders: Ted Love

A COVID-19 model

Microbiome therapeutics and patent protection

Gene editing

Focus on CRISPR tools and therapies

Around the world in a month

People

Danish bispecifics meet ADCs

The clinical cutting edge

Targeted, efficient sequence insertion and replacement in rice

A dual-constriction biological nanopore resolves homonucleotide sequences with high fidelity

Sequence-specific prediction of the efficiencies of adenine and cytosine base editors

Cell-free biosensors for rapid detection of water contaminants

The biopharmaceutical anomaly

The delivery challenge: fulfilling the promise of therapeutic genome editing

Programmable m6A modification of cellular RNAs with a Cas13-directed methyltransferase

A tissue-engineered uterus supports live births in rabbits

Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC–Cas9

Rapid image deconvolution and multiview fusion for optical microscopy

Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking

COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

The app credibility gap

The hothouse for protein design

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Publisher Correction: An engineered ScCas9 with broad PAM range and high specificity and activity

Blueprint for a pop-up SARS-CoV-2 testing lab

Scalable and robust SARS-CoV-2 testing in an academic center

Regulatory centaurs

CHANGE-seq reveals genetic and epigenetic effects on CRISPR–Cas9 genome-wide activity

Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis

A lipidome atlas in MS-DIAL 4

Publisher Correction: Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

A robust benchmark for detection of germline large deletions and insertions

Publisher Correction: Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

3D and 4D bioprinted human model patenting and the future of drug development

Translating academic careers into industry healthcare professions

FDA approves first RET inhibitor

Around the world in a month

Coronaviruses

Dyno advances AI-powered gene therapy

People

Genomic search for COVID-19 severity clues

Prediction of the sequence-specific cleavage activity of Cas9 variants

Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures

Coronavirus vaccine developers wary of errant antibodies

Publisher Correction: Base editors for simultaneous introduction of C-to-T and A-to-G mutations

Author Correction: Plants with genetically encoded autoluminescence

The COVID-19 testing debacle

A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing

Dual base editor catalyzes both cytosine and adenine base conversions in human cells