Terkko Navigator / Molecular Psychiatry

Differential regulation of alcohol consumption and reward by the transcriptional cofactor LMO4

Robust and replicable measurement for prepulse inhibition of the acoustic startle response

Hippocampal TNF-death receptors, caspase cell death cascades, and IL-8 in alcohol use disorder

Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model

Functional connectome-wide associations of schizophrenia polygenic risk

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

Greater cortical thickness in individuals with ASD

Tet3 ablation in adult brain neurons increases anxiety-like behavior and regulates cognitive function in mice

Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4

Kappa opioid receptor and dynorphin signaling in the central amygdala regulates alcohol intake

Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure

Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury

C/EBPβ/δ-secretase signaling mediates Parkinson’s disease pathogenesis via regulating transcription and proteolytic cleavage of α-synuclein and MAOB

Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions

[11C]PBR28 MR–PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder

Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities

Nucleus accumbens fast-spiking interneurons in motivational and addictive behaviors

Structural and functional imaging markers for susceptibility to psychosis

The dentate gyrus in depression: directions for future research

GWAS significance thresholds for deep phenotyping studies can depend upon minor allele frequencies and sample size

Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder

Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype

Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility

A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome

Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids

Early-life trauma endophenotypes and brain circuit–gene expression relationships in functional neurological (conversion) disorder

Genetic control of variability in subcortical and intracranial volumes

The origin of our modern concept of mania in texts from 1780 to 1900

Nuclear receptor corepressors in intellectual disability and autism

DNA methylation signature on phosphatidylethanol, not on self-reported alcohol consumption, predicts hazardous alcohol consumption in two distinct populations

Hippocampal subregions and networks linked with antidepressant response to electroconvulsive therapy

The changing opioid crisis: development, challenges and opportunities

The genetics of drug-related movement disorders, an umbrella review of meta-analyses

LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia

Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

Depression phenotype identified by using single nucleotide exact amplicon sequence variants of the human gut microbiome

Regional and temporal miRNAs expression profile in a transgenic mouse model of tauopathy: implication for its pathogenesis

SorCS2 is required for social memory and trafficking of the NMDA receptor

Success and efficiency of phase 2/3 adjunctive trials for MDD funded by industry: a systematic review

A psychiatric disease-related circular RNA controls synaptic gene expression and cognition

Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Hippocampal neural stem cells and microglia response to experimental inflammatory bowel disease (IBD)

Spontaneous hyperactivity in Ash1l mutant mice, a new model for Tourette syndrome

Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line

An integrated meta-analysis of peripheral blood metabolites and biological functions in major depressive disorder

The importance of a developmental perspective in Psychiatry: what do recent genetic-epidemiological findings show?

MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

Magnitude and heterogeneity of brain structural abnormalities in 22q11.2 deletion syndrome: a meta-analysis

Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice