Terkko Navigator / Molecular Oncology

The transmembrane protein LRIG1 triggers melanocytic tumor development following chemically induced skin carcinogenesis

Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks

The levels of soluble cMET ectodomain in the blood of patients with ovarian cancer are an independent prognostic biomarker

Vitamin D supplementation to the older adult population in Germany has the cost‐saving potential of preventing almost 30 000 cancer deaths per year

The direct miR‐874‐3p‐target FAM84A promotes tumor development in papillary thyroid cancer

LncRNA‐ZXF1 regulated P21 expression in endometrioid endometrial carcinoma by managing ubiquitination‐mediated degradation and miR‐378a‐3p/PCDHA3 axis

Single‐cell transcriptomics reveal the intratumoral landscape of infiltrated T‐cell subpopulations in oral squamous cell carcinoma

Doxorubicin‐induced senescence promotes stemness and tumorigenicity in EpCAM−/CD133− nonstem cell population in hepatocellular carcinoma cell line, HuH‐7

Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma

Therapeutic targeting with DABIL‐4 depletes myeloid suppressor cells in 4T1 triple‐negative breast cancer model

Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS‐mitochondrial fission‐mitophagy axis

How to make better use of scientific knowledge for cancer prevention

Behavioural and structural interventions in cancer prevention: towards the 2030 SDG horizon

Tackling the cancer burden: the economic impact of primary prevention policies

The eleventh hour to enforce rigorous primary cancer prevention

Issue Information

Tobacco control policies in the 21st century: achievements and open challenges

Climate change and cancer: converging policies

Occupational cancer burden: the contribution of exposure to process‐generated substances at the workplace

Vaccination against HPV: boosting coverage and tackling misinformation

Physical activity, obesity and sedentary behavior in cancer etiology: epidemiologic evidence and biologic mechanisms

The miR‐19b‐3p‐MAP2K3‐STAT3 feedback loop regulates cell proliferation and invasion in esophageal squamous cell carcinoma

Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma

Cancer‐associated fibroblasts promote tumor progression by lncRNA‐mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma

Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors

Liquid biopsy reveals KLK3 mRNA as a prognostic marker for progression free survival in patients with metastatic castration‐resistant prostate cancer undergoing first‐line abiraterone acetate and prednisone treatment

Long non‐coding RNA SNHG1 stimulates ovarian cancer progression by modulating expression of miR‐454 and ZEB1

Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR‐874‐3P/ATG16L1 axis

The RNA‐helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma

Small extracellular vesicles deliver TGF‐β1 and promote adriamycin resistance in breast cancer cells

Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies

A novel diphtheria toxin‐based bivalent human EGF fusion toxin for treatment of head and neck squamous cell carcinoma

Artificial intelligence in cancer research: learning at different levels of data granularity

The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas

A combination of extracellular matrix‐ and interferon‐associated signatures identifies high‐grade breast cancers with poor prognosis

EWI‐2 controls nucleocytoplasmic shuttling of EGFR signaling molecules and miRNA sorting in exosomes to inhibit prostate cancer cell metastasis

Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer

Irradiation‐induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis

Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets

Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis

LncRNA NKX2‐1‐AS1 promotes tumor progression and angiogenesis via upregulation of SERPINE1 expression and activation of the VEGFR‐2 signaling pathway in gastric cancer

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia

DNA methylation markers have universal prognostic value for anal cancer risk in HIV‐negative and HIV‐positive individuals

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

Insights into the molecular profiles of adult and paediatric acute myeloid leukaemia

IFNβ1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment

A novel circular RNA, hsa_circ_0030998 suppresses lung cancer tumorigenesis and Taxol resistance by sponging miR‐558

Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling

A novel prognostic mRNA/miRNA signature for esophageal cancer and its immune landscape in cancer progression