Table of Contents

Managing kidney injury in older patients.
Incidence, risk factors, and outcome.
Assessing glomerular filtration rate in older adults.
Risk assessment and diagnostic criteria of acute kidney injury: the role of tubular damage markers.
Pathogenesis and susceptibility to injury.
Drug kinetics, dosing, and renal toxicity in older adults.
Acute dialysis in older patients.
Quality of life, functional status, and specific medical problems in older patients.
End-of-life decision making in older patients with acute kidney injury and end-stage renal disease: ethical perspectives. As the number of people aged 65 years and above rises, physicians are increasingly confronted by elderly patients with impaired renal function, altered drug metabolism and multiple comorbidities. This book examines in detail the nature of renal injury in the elderly and its optimal management. A wide range of key topics are covered, including end-stage renal disease, diabetic nephropathy, acute kidney injury, drug metabolism and renal toxicity, dialysis and its complications and the use of renal transplantation. In addition, the assessment of glomerular filtration rate in the elderly and the role of novel renal biomarkers are carefully examined. Quality of life issues, the significance of other age-related medical problems and end of life care are also discussed. This book will be of value not only to nephrologists but also to general practitioners, medical students, intensivists, cardiologists, pharmacologists and those working in related specialties.