Terkko Navigator / Life Science Alliance

Growth-rate-dependent and nutrient-specific gene expression resource allocation in fission yeast

The expression of essential selenoproteins during development requires SECIS-binding protein 2-like

Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs

Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors

ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells

Visualized procollagen I{alpha}1 demonstrates the intracellular processing of propeptides

Quantitative profiling of adaptation to cyclin E overproduction

Angioplasty induces epigenomic remodeling in injured arteries

The m6A(m)-independent role of FTO in regulating WNT signaling pathways

Muscle stem cell polarity requires QKI-mediated alternative splicing of Integrin Alpha-7 (Itga7)

Human BRCA pathogenic variants were originated during recent human history

MMD-associated RNF213 SNPs encode dominant-negative alleles that globally impair ubiquitylation

Environmental control of Pub1 (NEDD4 family E3 ligase) in Schizosaccharomyces pombe is regulated by TORC2 and Gsk3

Proteomic landscape of SARS-CoV-2- and MERS-CoV-infected primary human renal epithelial cells

Refining the domain architecture model of the replication origin firing factor Treslin/TICRR

Cis-regulatory hubs: a new 3D model of complex disease genetics with an application to schizophrenia

Recruitment of Scc2/4 to double-strand breaks depends on {gamma}H2A and DNA end resection

Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting

Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures

Nucleotide biosynthesis links glutathione metabolism to ferroptosis sensitivity

Phenylbutyrate rescues the transport defect of the Sec61{alpha} mutations V67G and T185A for renin

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells

Malaria abrogates Onyong-nyong virus pathologies by restricting virus infection in nonimmune cells

Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques

Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF

Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding

Testing of the therapeutic efficacy and safety of AMPA receptor RNA aptamers in an ALS mouse model

Identification of human gene research articles with wrongly identified nucleotide sequences

Structural basis of Nrd1-Nab3 heterodimerization

Chl1 helicase controls replication fork progression by regulating dNTP pools

Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19

Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH

Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension

New insights into the phosphorylation of the threonine motif of the {beta}1 integrin cytoplasmic domain

Rbfox1 is required for myofibril development and maintaining fiber type-specific isoform expression in Drosophila muscles

Retinoblastoma protein regulates carcinogen susceptibility at heterochromatic cancer driver loci

Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law

Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis

ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway

Electron cryo-tomography structure of axonemal doublet microtubule from Tetrahymena thermophila

Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting

Poly(ADP-ribosyl)ating pathway regulates development from stem cell niche to longevity control

Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity

CNVs with adaptive potential in Rangifer tarandus: genome architecture and new annotated assembly

Loss of Nup210 results in muscle repair delays and age-associated alterations in muscle integrity

Fms-like tyrosine kinase 3 is a regulator of the cardiac side population in mice

Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans

Nonsense-mediated mRNA decay uses complementary mechanisms to suppress mRNA and protein accumulation

{beta}-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy

Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system