Terkko Navigator / Lehti, K(aisa)

Crosstalk Between Cancer Associated Fibroblasts and Cancer Cells in Scirrhous Type Gastric Cancer.

Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer.

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds.

High tissue MMP14 expression predicts worse survival in gastric cancer, particularly with a low PROX1.

MMP14 in Sarcoma: A Regulator of Tumor Microenvironment Communication in Connective Tissues.

A novel mutation in the matrix metallopeptidase 2 coding gene associated with intrafamilial variability of multicentric osteolysis, nodulosis, and arthropathy.

Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization.

FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.

An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy.

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage.

Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.

Lymphatic Vascular Structures: A New Aspect in Proliferative Diabetic Retinopathy.

Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton.

PROX1 is a transcriptional regulator of MMP14.

Fibroblasts in the Tumor Microenvironment: Shield or Spear?

A functional homologous recombination assay predicts primary chemotherapy response and long-term survival in ovarian cancer patients.

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 andβ1-integrin activation.

Microenvironment of proliferative diabetic retinopathy supports lymphatic neovascularization.

Membrane-type matrix metalloproteases as diverse effectors of cancer progression.

RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.

Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry.

Quantitative Proteomics Analysis of Vitreous Humor from Diabetic Retinopathy Patients.

Liprin-α1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery.

Proactive for invasion: Reuse of matrix metalloproteinase for structural memory.

Quantitative Proteomics Analysis of Vitreous Humor from Diabetic Retinopathy Patients.

A Case of Abnormal Lymphatic-Like Differentiation and Endothelial Progenitor Cell Activation in Neovascularization Associated with Hemi-Retinal Vein Occlusion.

Indications of lymphatic endothelial differentiation and endothelial progenitor cell activation in the pathology of proliferative diabetic retinopathy.

MMP16 mediates a proteolytic switch to promote cell-cell adhesion, collagen alignment, and lymphatic invasion in melanoma.

Identification of 33 candidate oncogenes by screening for base-specific mutations.

Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton.

Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics.

Increased intravitreal angiopoietin-2 levels associated with rhegmatogenous retinal detachment.

EphA2 bears plasticity to tumor invasion.

An optimized isolation of biotinylated cell surface proteins reveals novel players in cancer metastasis.

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.

Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGF?1 in diabetic eyes undergoing vitrectomy.

MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis.

KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase-Dependent Lymphatic Endothelial-to-Mesenchymal Transition.

Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion.

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor.

Syndecan-1 and -4 differentially regulate oncogenic K-ras dependent cell invasion into collagen through ?2?1 integrin and MT1-MMP.

Fibroblast Growth Factor Receptor 4 Regulates Tumor Invasion by Coupling Fibroblast Growth Factor Signaling to Extracellular Matrix Degradation.

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex.

MT1-MMP promotes vascular smooth muscle dedifferentiation through LRP1 processing.

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes.

MT1-MMP releases latent TGF-beta1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1.

Epilysin (MMP-28) induces TGF-beta mediated epithelial to mesenchymal transition in lung carcinoma cells.

An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature.

Plasmin activates pro-matrix metalloproteinase-2 with a membrane-type 1 matrix metalloproteinase-dependent mechanism.