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3 Conversations to Have About the Future Today

Identification Of Peptides Interfering The LRRK2/PP1 Interaction

A memory of RPS25 loss drives resistance phenotypes

Dis3L2 regulates cellular proliferation through a PI3-Kinase dependent signalling pathway

Extracellular ATP and CD39 activate cAMP-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia

AKT2 deficiency causes sarcopenia and metabolic disorder of skeletal muscle

Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements

DNA hydroxymethylation reveals transcription regulation networks and prognostic signatures in multiple myeloma

Exosomes transmit retroelement RNAs to drive inflammation and immunosuppression in Ewing Sarcoma

In vivo imaging defines vascular interplay in the development of lymphocytic leukemia in zebrafish models

Anti‐streptococcal antibody and T‐cell interactions with vascular endothelial cells initiate the development of rheumatic carditis

Weak correlations between serum and cerebrospinal fluid levels of estradiol, progesterone and testosterone in males

The world is not enough to explain lengthening of phonological competitors

Damping down brain cell activity may help us to live longer

Humans evolved to think faster by slowing down brain development

Reaping The Rewards Of Active Self-Reinforcement

Defining Value for Pancreatic Surgery in Early-Stage Pancreatic Cancer

Aggregating Pancreatic Cancer Care to Specialized Centers—A High-Value Decision?

Association of Residents' Neural Signatures With Stress Resilience During Surgery

JAMA Surgery

October 2019 In This Issue

USPSTF Breast Cancer Recommendation Statement on Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA -Related Cancer

Patient-Specific, 3-Dimensional Mixed-Reality Model Creation for Surgical Training and Decision-making

Surgical Smoke Exposure in Operating Room Personnel

Association Between Pancreatic Fistula and Long-term Survival in the Era of Neoadjuvant Chemotherapy

Perceptions of Surgery Residents About Parental Leave During Training

Efficacy of Prehospital Criteria in Identifying Trauma Patients Susceptible to Undertriage

Remembering the Hippocratic Oath in Surgical Training

Optimizing Joy in Surgery

Assessment of Surgical Specialty Societies' Choosing Wisely Recommendations

Primary Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma

Bleeding Control Basic Training Among Laypeople Applying Different Tourniquet Types

Safety and Benefit of Using Liver Grafts From Older Donors—Reply

Safety and Benefit of Using Liver Grafts From Older Donors

Safety and Benefit of Using Liver Grafts From Older Donors

Validation of Zip Code–Based Estimate of Ambulance Driving Distance and Access to Care in Emergency Surgery Research

Neoadjuvant Therapy and Surgery for Locally Invasive Pancreatic Cancer

Prehospital Hemorrhage Control—Leveraging Successes From Cardiac Arrest to Optimize Population-Level Effectiveness

Heart Failure and Postoperative Mortality After Ambulatory Noncardiac Surgery

How Implementation Science in Surgery Is Done

Association of Surgical Work Measures and Specialty With Relative Value Units

More Objective Data to Determine RVUs for Surgical Effort

Cancer and Other Outcomes After Surgery With Fluoridated Anesthesia—Reply

Cancer and Other Outcomes After Surgery With Fluoridated Anesthesia

Trends in Diverting Loop Ileostomy vs Total Abdominal Colectomy as Surgical Management for Clostridium difficile Colitis

Hawthorne Effect Should Be Controlled for in Quality Control Studies—Reply

Hawthorne Effect Should Be Controlled for in Quality Control Studies

Loop Ileostomy vs Total Abdominal Colectomy—A Valid Alternative?

Revisions of Gastric Bypass—A Moral Obligation—Reply

Revisions of Gastric Bypass—A Moral Obligation