Table of Contents

Front Cover; Laboratory Animal Medicine; Copyright Page; Contents; List of Reviewers; List of Contributors; Preface to the Third Edition; 1 Laboratory Animal Medicine: Historical Perspectives; I. Introduction; II. Origins of Animal Experimentation; III. Early Veterinarians in Laboratory Animal Science and Medicine; IV. The Organizations of Laboratory Animal science; A. Background; B. The National Society for Medical Research; C. The American Association for Laboratory Animal Science; D. The Institute for Laboratory Animal Research; E. The American College of Laboratory Animal Medicine 1. Institute for Laboratory Animal Research2. AAALAC International; 3. Federation of Animal Science Societies; 4. Other Professional Organizations; H. International Laws and Regulations; 1. The World Organisation for Animal Health (OIE); 2. Council for International Organizations of Medical Sciences (CIOMS); III. Importation and Exportation of Animals and Animal Products; A. U.S. Department of Agriculture; B. U.S. Department of Health and Human Services; C. U.S. Department of the Interior; D. Environmental Protection Agency E. Animal Transportation Association and International Air Transport AssociationIV. Hazardous Substances; A. Biohazards; B. Chemical Agents; C. Radioactive Materials and Radiation-Emitting Equipment; V. Nucleic Acid and Nanomaterial Research Guidelines; References; 3 Biology and Diseases of Mice; I. Introduction; A. Origin and History; B. Genetic History; C. Genetics; D. Breeding Systems; E. Induced Mutant Mice (Genetically Engineered Mice); 1. Engineered Endonuclease Technologies; F. Nomenclature; G. Housing, Husbandry, and Nutrition; 1. Housing and Husbandry; 2. Nutrition; II. Biology F. The American Society of Laboratory Animal PractitionersG. The Association of Primate Veterinarians; H. The International Association of Colleges of Laboratory Animal Medicine; V. Education and Training in Laboratory Animal Medicine; VI. ACLAM-Sponsored Texts; VII. Impact of Laws, Regulations, and Guidelines on Laboratory Animal Medicine; VIII. Regulation of Animal Research in the United Kingdom and Canada; IX. Commercial and Academic Breeding of Rodents; X. Conclusion; Acknowledgment; References; 2 Laws, Regulations, and Policies Affecting the Use of Laboratory Animals; I. Introduction II. Animal WelfareA. U.S. Animal Welfare Act; 1. USDA Regulations; Regulated Species; Licensing; Registration; IACUC Responsibilities; Personnel Qualifications; Information Services; Attending Veterinarian; Records; 2. USDA Standards; Canine Opportunity for Exercise; Psychological Well-Being of Nonhuman Primates; 3. USDA Enforcement; B. Public Health Service Policy; C. FDA Good Laboratory Practices; D. Federal Interagency Cooperation; E. EPA Good Laboratory Practices; F. FWS and NIH Positions on Chimpanzees; G. Professional and Scientific Associations Laboratory Animal Medicine, Third Edition, is a fully revised publication from the American College of Laboratory Medicine's acclaimed blue book series. It presents an up-to-date volume that offers the most thorough coverage of the biology, health, and care of laboratory animals. The book is organized by species, with new inclusions of chinchillas, birds, and program and employee management, and is written and edited by known experts in the fields. Users will find gold-standard guidance on the study of laboratory animal science, as well as valuable information that applies across all of the biological and biomedical sciences that work with animals.