Terkko Navigator / Klefström, J(uha)*

Oncogenic Ras disrupts epithelial integrity by activating the transmembrane serine protease hepsin.

Assessment of the WAP-Myc mouse mammary tumor model for spontaneous metastasis.

UBR5 is co-amplified with MYC in breast tumors and encodes an ubiquitin ligase that limits MYC-dependent apoptosis.

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.

Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology.

Design, synthesis and testing of potent, selective hepsin inhibitors via application of an automated closed-loop optimization platform.

Phenotype-driven identification of epithelial signalling clusters.

Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture.

MYC and AMPK-Save Energy or Die!

Myc requires RhoA/SRF to reprogram glutamine metabolism.

Data integration to prioritize drugs using genomics and curated data.

MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures.

Par6 family proteins in cancer.

Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation.

Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion.

Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers.

Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.

Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2.

Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells.

Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4.

Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis.

Impact of Epithelial Organization on Myc Expression and Activity--Letter.

Faulty epithelial polarity genes and cancer.

Regulation of Cell death in Human Fetal and Adult Ovaries - Role of Bok and Bcl-X(L).

GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis.

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation.

3D view to tumor suppression: Lkb1, polarity, and the arrest of oncogenic c-Myc.

Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer.

c-Myc Blazing a Trail of Death: Coupling of the Mitochondrial and Death Receptor Apoptosis Pathways by c-Myc.

Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization.

c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis.

[Lentiviruses to use]

Similarities between TNF and exogenous oxidants on the cytotoxic response of c-Myc-expressing fibroblasts in vitro.

Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia.

The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo.

c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway.

c-Myc and E1A induced cellular sensitivity to activated NK cells involves cytotoxic granules as death effectors.

Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kappaB activation.

BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma.

c-Myc induces cellular susceptibility to the cytotoxic action of TNF-alpha.

Major and minor breakpoint sites of chromosomal translocation t(14;18) in subtypes of non-Hodgkin's lymphomas.

Two novel human B-cell lymphoma lines of lymphatic follicle origin: cytogenetic, molecular genetic and histopathological characterisation.

Myc protein: partners and antagonists.

A sub-set of immediate early mRNAs induced by tumor necrosis factor-alpha during cellular cytotoxic and non-cytotoxic responses.

[Complex mechanics of tumor-necrosis-factor-induced cell death]

[The use of polymerase chain reaction in the diagnosis of non-Hodgkin's lymphoma]

Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.