Table of Contents

Epidemiology of IGF-1 and Cancer.
Aging and Cancer: The IGF-I Connection.
Obesity, Type 2 Diabetes and Cancer.
IGF System and Breast Cancer.
The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression.
IGF-1 Cellular Action and its Relationship to Cancer: Evidence from in Vitro and in Vivo Studies.
Insulin-Like Growth Factor Signaling in Pediatric Sarcomas.
Cancer Genes, Tumor Suppressors, and Regulation of IGF1-R Gene Expression in Cancer.
Mouse Models of IGF-1R and Cancer.
Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy.
Targeting Insulin-Like Growth Factor Receptor 1 (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer.
Calories and Cancer: The Role of Insulin-Like Growth Factor-1.
Cancer Cell Metabolism.
Overlaps Between the Insulin and IGF-I Receptor and Cancer.