Terkko Navigator / Infection and Immunity

Cooperative roles of NO-metabolizing enzymes to counteract nitrosative stress in enterohemorrhagic Escherichia coli.

Contribution of hla regulation by SaeR to Staphylococcus aureus USA300 Pathogenesis.

Participation of the serine protease Jonah66Ci in the Drosophila anti-nematode immune response.

Persistent Toxoplasma Infection of the Brain Induced Neurodegeneration associated with Activation of Complement and Microglia.

Intradermal synDNA vaccination generates Leishmania specific T cells in the skin and protection against Leishmania major.

Evaluation of the protective ability of the Treponema pallidum subspecies pallidum Tp0126 OmpW homolog in the rabbit model of syphilis.

PhiA, a peptidoglycan hydrolase inhibitor of Brucella involved in the virulence process.

miR155 contributes to host immunity against L. donovani but is not essential for resolution of infection.

Distinct roles of chromosome- versus plasmid-encoded genital tract virulence factors in promoting Chlamydia muridarum colonization in the gastrointestinal tract.

New perspectives on Galleria mellonella larvae as a host model using Riemerella anatipestifer as a proof of concept.

NF-κB RelA is required for hepatoprotection during pneumonia and sepsis.

Caspase-11 contributes to oviduct pathology during genital Chlamydia infection in mice.

Neisseria meningitidis type IV pili trigger Ca2+-dependent lysosomal trafficking of the acid sphingomyelinase to enhance surface ceramide levels.

A chemical genetics screen reveals influence of p38 map kinase and autophagy on phagosome development and intracellular replication of Brucella neotomae in macrophages.

Schistosoma mansoni worm infection regulates the intestinal microbiota and susceptibility to colitis.

Vaccination against Clostridium difficile using an attenuated Salmonella Typhimurium vector (YS1646) protects mice from lethal challenge.

Deficient skeletal muscle regeneration after injury induced by a Clostridium perfringens strain associated with gas gangrene.

Viral co-infection replaces effects of suilysin on adherence and invasion of Streptococcus suis into respiratory epithelial cells grown under air-liquid interface conditions.

Deletion of a 19-amino acid region in Clostridioides difficile TcdB2 results in spontaneous autoprocessing, reduced cell binding, and provides a non-toxic immunogen for vaccination.

Bacterial microcompartment-mediated ethanolamine metabolism in E. coli urinary tract infection.

Activation of the endoplasmic reticulum stress response impacts the NOD1 signaling pathway.

On the role of toll-like receptor 5 (TLR5) in experimental melioidosis.

Serum IgM and C-reactive protein binding to phosphorylcholine of non-typeable Haemophilus influenzae increases complement-mediated killing.

Aggregatibacter actinomycetemcomitans leukotoxin (LtxA; Leukothera®) requires death receptor Fas, in addition to LFA-1, to trigger cell death in T lymphocytes.

CD40 in endothelial cells restricts neural tissue invasion by Toxoplasma gondii.

A Protein E-PilA fusion protein shows vaccine potential against nontypeable Haemophilus influenzae in mice and chinchillas.

Design and characterization of PE-PilA, a candidate fusion antigen for non-typeable Haemophilus influenzae vaccine.

Spectrum of Trained Innate Immunity Induced by Low Virulence Candida Species Against Lethal Polymicrobial Intra-Abdominal Infection.

Modeling pneumonic plague in human precision-cut lung slices highlights a role for the plasminogen activating protease in facilitating type 3 secretion.

Chlamydia induces pathology in the female upper genital tract via distinct mechanisms.

T-Cell Immunophenotyping and Cytokine Production Analysis in Patients with Chagas Disease 4 Years after Benznidazole Treatment.

Dietary polyunsaturated fatty acids promote neutrophil accumulation in spleen by altering chemotaxis and delaying cell death.

Delineating surface epitopes of Lyme disease pathogen targeted by highly protective antibodies of New Zealand White rabbits.

Salmonella typhimurium interacts with CD209 receptors to promote host dissemination and infection.

The Ser/Thr kinase PrkC participates in cell wall homeostasis and antimicrobial resistance in Clostridium difficile.

Development, characterization and standardization of a nose-only inhalation exposure system for exposure of rabbits to small particle aerosols containing Francisella tularensis.

Citrobacter rodentium induces tissue-resident memory CD4+ T-cells.

Immunizations with enterotoxigenic Escherichia coli heat-stable toxin conjugates engender toxin-neutralizing antibodies in mice that also cross-react with guanylin and uroguanylin.

Interleukin 1 receptor like 1 (IL1RL1) promotes airway bacterial and viral infection and inflammation.

Non-helical Helicobacter pylori show altered gland colonization and elicit less gastric pathology during chronic infection.

NanI Sialidase Is an Important Contributor to Clostridium perfringens Type F Strain F4969 Intestinal Colonization in Mice.

Tamm-Horsfall Protein Protects the Urinary Tract against Candida albicans.

Polymorphisms in Receptors Involved in Opsonic and Nonopsonic Phagocytosis, and Correlation with Risk of Infection in Oncohematology Patients.

Deletion of Interleukin-4 Receptor Alpha-Responsive Keratinocytes in BALB/c Mice Does Not Alter Susceptibility to Cutaneous Leishmaniasis.

Cross Talk between MarR-Like Transcription Factors Coordinates the Regulation of Motility in Uropathogenic Escherichia coli.

Tracking Anti-Staphylococcus aureus Antibodies Produced In Vivo and Ex Vivo during Foot Salvage Therapy for Diabetic Foot Infections Reveals Prognostic Insights and Evidence of Diversified Humoral Immunity.

Treatment of Dextran Sulfate Sodium-Induced Colitis with Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor MI-2 Is Associated with Restoration of Gut Immune Function and the Microbiota.

Autoinducer 2 (AI-2) Production by Nontypeable Haemophilus influenzae 86-028NP Promotes Expression of a Predicted Glycosyltransferase That Is a Determinant of Biofilm Maturation, Prevention of Dispersal, and Persistence In Vivo.

Improved Tolerability of a Salmonella enterica Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity.

Heterogeneity of Ly6G+ Ly6C+ Myeloid-Derived Suppressor Cell Infiltrates during Staphylococcus aureus Biofilm Infection.