Table of Contents

Introduction: Overview, History, Terminology and Early Clinical Experience.
The Principle of Dose-Response in Antineoplastic Drug Delivery.
Drug Removal Systems and Induction Chemotherapy.
Cryotherapy.
Local and Regional Hyperthermia.
The Role of Hypoxia and Hyperthermia in Chemotherapy.
Induction Chemotherapy in Head and Neck Cancers.
Isolated Thoracic Perfusion with Carotid Artery Infusion for Advanced and Chemoresistant Tumors of the Parotid Gland.
Induction Systemic Chemotherapy for Breast Cancer.
Induction Intra-arterial Chemotherapy (IAC) with Epirubicin and Mitoxantrone in Locally Advanced Breast Cancer.
Induction Bidirectional Chemotherapy for Gastric Cancer with Peritoneal Dissemination.
Gastric Cancer.
Esophageal Cancer.
Regional Chemotherapy for Recurrent Platin Refractory Ovarian Cancer.
Penile Cancer Treated by Intra-aortic Infusion Chemotherapy.
Isolated Limb Perfusion for Melanoma.
Interventional Radiological Procedures for Port-Catheter Implantation.
Induction Chemotherapy for Hepatocellular Carcinoma.
Systemic Induction Chemotherapy for Advanced Stage Epithelial Ovarian Cancer.
Induction Chemotherapy for Cervical Cancer.
Induction Treatment in Sarcomas.
Induction Chemotherapy in Treatment of Sarcomas.
Liver Metastases.
Isolated Thoracic Perfusion with Chemofiltration (ITP-F) for Advanced and Pre-treated Non-Small-Cell Lung Cancer.
Isolation Perfusion Systems: Lungs.
Metastatic Cancers in Lung: Isolated Lung Perfusion.
Clinical Studies.
Systemic and Regional Chemotherapy for Advanced and Metastasized Pancreatic Cancer.
Conclusion.