Table of Contents

Primer on immunoendocrinology.
Discovering novel antigens.
Developing and validating high sensitivity/specificity autoantibody assays.
Characterizing T-cell autoimmunity.
Metabolic syndrome and inflammation.
The mouse model of autoimmune polyglandular syndrome type 1.
Autoimmune polyendocrine syndrome type 1: man.
IPEX syndrome: clinical profile, biological features, and current treatment.
Autoimmune polyendocrine syndrome type 2: pathophysiology, natural history, and clinical manifestations.
Drug-induced endocrine autoimmunity.
The BB rat.
Immunopathogenesis of the NOD mouse.
Virus-induced type 1 diabetes in the rat.
Autoimmune pathology of type 1 diabetes.
Genetics of type 1 diabetes: immunoendocrinology: scientific and clinical aspects.
Epidemiology of type 1 diabetes.
Natural history of type 1 diabetes.
Immunotherapy of type 1 diabetes: immunoprevention and immunoreversal.
Latent autoimmune diabetes in adults.
Fulminant type 1 diabetes mellitus.
Insulin autoimmune syndrome (Hirata disease).
Lessons from patients with anti-insulin receptor autoantibodies.
Islet and pancreas transplantation.
Addison's disease.
Animal models of autoimmune thyroid disease.
Genetics of thyroid autoimmunity.
Immunopathogenesis of thyroiditis.
Immunopathogenesis of Graves's disease.
Graves' ophthalmopathy.
Hypoparathyroidism.
Premature gonadal insufficiency.
Celiac disease and intestinal endocrine autoimmunity.
Pituitary autoimmunity. Immunoendocrinology is a rapidly developing field of research that seeks to understand the intersection of the immune and endocrine systems. "Immunoendocrinology: Scientific and Clinical Aspects" explores in detail the current knowledge of immunoendocrinology, namely endocrine disorders produced by disorders of immune function. Chapters cover both basic pathophysiology informed by studies of animal models as well as current understanding of multiple related clinical diseases - their pathophysiology, diagnosis, and therapy. "Immunoendocrinology: Scientific and Clinical Aspects & qu.