Table of Contents

General concepts and administrative issues.
Optimizing laboratory workflow and performance.
Preanalysis.
Analysis : principles of instrumentation.
Analysis : clinical laboratory automation.
Point-of-care testing and physician office laboratories.
Postanalysis : medical decision making.
Interpreting laboratory results.
Laboratory statistics.
Quality control.
Clinical laboratory informatics.
Financial management.
Biological, chemical, and nuclear terrorism : role of the laboratory.
Evaluation of renal function, water, electrolytes, and acid-base balance.
Biochemical markers of bone metabolism.
Carbohydrates.
Lipids and dyslipoproteinemia.
Cardiac injury, atherosclerosis, and thrombotic disease.
Specific proteins.
Clinical enzymology.
Evaluation of liver function.
Laboratory diagnosis of gastrointestinal and pancreatic disorders.
Toxicology and therapeutic drug monitoring.
Evaluation of endocrine function.
Reproductive function and pregnancy.
Vitamins and trace elements.
Chemical basis for analyte assays and common interferences.
Basic examination of urine.
Cerebrospinal, synovial, serous body fluids, and alternative specimens.
Basic examination of blood and bone marrow.
Hematopoiesis.
Erythrocytic disorders.
Leukocytic disorders.
The flow cytometric evaluation of hematopoietic neoplasia.
Immunohematology.
Transfusion medicine.
Hemapheresis.
Tissue banking and progenitor cells.
Coagulation and fibrinolysis.
Platelet disorders and von Willebrand disease.
Laboratory approach to thrombotic risk.
Antithrombotic therapy.
Overview of the immune system and immunologic disorders.
Immunoassays and immunochemistry.
Laboratory evaluation of the cellular immune system.
Laboratory evaluation of immunoglobulin function and humoral immunity.
Mediators of inflammation : complement, cytokines, and adhesion molecules.
Mediators of inflammation : cytokines and adhesion molecules.
Human leukocyte antigen : the major histocompatibility complex of man.
The major histocompatibility complex and disease.
Immunodeficiency disorders.
Clinical and laboratory evaluation of systemic rheumatic diseases.
Vasculitis.
Organ-specific autoimmune diseases.
Allergic diseases.
Viral infections.
Chlamydial, rickettsial, and mycoplasmal infections.
Medical bacteriology.
In vitro testing of antimicrobial agents.
Spirochete infections.
Mycobacteria.
Mycotic diseases.
Specimen collection and handling for diagnosis of infectious diseases.
Introduction to molecular pathology.
Molecular diagnostics : basic principles and techniques.
Polymerase chain reaction and other nucleic acid amplification technology.
Hybridization array technologies.
Applications of cytogenetics in modern pathology.
Establishing a molecular diagnostics laboratory.
Molecular diagnosis of genetic diseases.
Identity analysis : use of DNA analysis in parentage, forensic, and missing persons testing.
Pharmacogenomics and personalized medicine.
Diagnosis and management of cancer using serologic and other body fluid markers.
Oncoproteins and early tumor detection.
Molecular diagnosis of hematopoietic neoplasms.
Molecular genetic pathology of solid tumors.
High-throughput genomic and proteomic technologies in the postgenomic era.
Physiologic solutions, buffers, acid-base indicators, standard reference materials, and temperature conversions.
Desirable weights, body surface area, and body mass index.
Approximations of total blood volume.
Periodic table of the elements.
SI units.
Common chimeric genes identified in human malignancies.
Disease/organ panels.
Guidelines for ordering blood for elective surgery. Recognized as the definitive reference in laboratory medicine since 1908, Henry's Clinical Diagnosis continues to offer state-of-the-art guidance on the scientific foundation and clinical application of today's complete range of laboratory tests. Employing a multidisciplinary approach, it presents the newest information available in the field, including new developments in technologies and the automation platforms on which measurements are performed.