Terkko Navigator / Hemminki, A(kseli)*

TNFa and IL-2 armed adenoviruses enable complete responses by anti-PD-1 checkpoint blockade.

Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses.

Interleukin 8 activity influences the efficacy of adenoviral oncolytic immunotherapy in cancer patients.

Familial associations of male breast cancer with other cancers.

Familial associations of female breast cancer with other cancers.

Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102 - Support for clinical studies on advanced cancer treatment.

Familial Associations of Colorectal Cancer with Other Cancers.

Other cancers in lung cancer families are overwhelmingly smoking-related cancers.

Adenoviral production of interleukin-2 at the tumor site removes the need for systemic postconditioning in adoptive cell therapy.

Genetics of gallbladder cancer.

Cancer-targeted oncolytic adenoviruses for modulation of the immune system.

TILT Biotherapeutics.

Power and limits of modern cancer diagnostics: cancer of unknown primary.

Risk of other Cancers in Families with Melanoma: Novel Familial Links.

Dasatinib changes immune cell profiles concomitant with reduced tumor growth in several murine solid tumor models.

Concordant and discordant familial cancer: Familial risks, proportions and population impact.

Multimodal Primary Treatment of Metastatic Prostate Cancer with Androgen Deprivation and Radiation.

Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus.

T-Cell Therapy Enabling Adenoviruses Coding for IL2 and TNFα Induce Systemic Immunomodulation in Mice With Spontaneous Melanoma.

Common cancers share familial susceptibility: implications for cancer genetics and counselling.

Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity.

The epidemiology of metastases in neuroendocrine tumors.

Familial Associations Between Prostate Cancer and Other Cancers.

Syngeneic syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting.

Oncolytic adenovirus expressing monoclonal antibody trastuzumab for treatment of HER2-positive cancer.

Metastatic spread in patients with gastric cancer.

Patterns of metastasis in colon and rectal cancer.

Adenoviral delivery of tumor necrosis factor alpha and interleukin-2 enables successful adoptive cell therapy of immunosuppressive melanoma.

Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

Oncolytic virotherapy for treatment of breast cancer, including triple-negative breast cancer.

A century of oncolysis evolves into oncolytic immunotherapy.

Predictive and prognostic clinical variables in cancer patients treated with adenoviral oncolytic immunotherapy.

Phase I study with ONCOS-102 for the treatment of solid tumors - an evaluation of clinical response and exploratory analyses of immune markers.

Location of metastases in cancer of unknown primary are not random and signal familial clustering.

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death.

Chronic activation of innate immunity correlates with poor prognosis in cancer patients treated with oncolytic adenovirus.

Population Landscape of Familial Cancer.

Attenuated Semliki Forest virus for cancer treatment in dogs: safety assessment in two laboratory Beagles.

Biodistribution analysis of oncolytic adenoviruses in patient autopsy samples reveals vascular transduction of non-injected tumors and tissues.

Adenovirus improves the efficacy of adoptive T-cell therapy by recruiting immune cells to and promoting their activity at the tumor.

Serum HMGB1 is a predictive and prognostic biomarker for oncolytic immunotherapy.

Consensus guidelines for the detection of immunogenic cell death.

Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polarization.

Treatment of melanoma with a serotype 5/3 chimeric oncolytic adenovirus coding for GM-CSF: Results in vitro, in rodents and in humans.

Incomplete but Infectious Vaccinia Virions Are Produced in the Absence of Oncolysis in Feline SCCF1 Cells.

Immunological data from cancer patients treated with Ad5/3 E2FΔ24 GMCSF suggests utility for tumor immunotherapy.

T cell subsets in peripheral blood and tumors of patients treated with oncolytic adenoviruses.

Immunological effects of a TNF-alpha armed oncolytic adenovirus.

Case-control estimation of the impact of oncolytic adenovirus on the survival of patients with refractory solid tumors.

Anti-tumour activity of oncolytic Western Reserve vaccinia viruses in canine tumour cell lines, xenografts, and fresh tumour biopsies.