Terkko Navigator / GeroScience

Rapamycin restores brain vasculature, metabolism, and blood-brain barrier in an inflammaging model

Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice

Results of a hospitalization policy of asymptomatic and pre-symptomatic COVID-19-positive long-term care facility residents in the province of Salzburg-a report from the AGMT COVID-19 Registry

Sensory and memory processing in old female and male Wistar rat brain, and its relationship with the cortical and hippocampal redox state

The trophocytes and oenocytes of worker and queen honey bees (Apis mellifera) exhibit distinct age-associated transcriptome profiles

A ride through the epigenetic landscape: aging reversal by reprogramming

In vivo proton magnetic resonance spectroscopy detection of metabolite abnormalities in aged Tat-transgenic mouse brain

Proceedings from the annual University of Washington Geroscience Symposium, October 23, 2020

Reversal of cerebral hypoperfusion: a novel therapeutic target for the treatment of AD/ADRD?

Lifelong exercise is associated with more homogeneous motor unit potential features across deep and superficial areas of vastus lateralis

Longitudinal course of GDF15 levels before acute hospitalization and death in the general population

Skeletal muscle mitochondrial DNA copy number and mitochondrial DNA deletion mutation frequency as predictors of physical performance in older men and women

Effects of metformin, rapamycin, and resveratrol on cellular metabolism of canine primary fibroblast cells isolated from large and small breeds as they age

Deletion of Nrip1 delays skin aging by reducing adipose-derived mesenchymal stem cells (ADMSCs) senescence, and maintaining ADMSCs quiescence

Intermittent fasting: from calories to time restriction

Late-life intermittent fasting decreases aging-related frailty and increases renal hydrogen sulfide production in a sexually dimorphic manner

IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging

Cardiac response to adrenergic stress differs by sex and across the lifespan

Circulating fatty acids and endocannabinoidome-related mediator profiles associated to human longevity

Age-related neuroendocrine and alerting responses to light

Targeting mitochondrial dysfunction with small molecules in intervertebral disc aging and degeneration

Lack of resemblance between Myhre syndrome and other "segmental progeroid" syndromes warrants restraint in applying this classification

IL-6 can singlehandedly drive many features of frailty in mice

Temporal emergence of age-associated changes in cognitive and physical function in vervets (Chlorocebus aethiops sabaeus)

Implication of post-translationally modified SOD1 in pathological aging

A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts

Longitudinal uncoupling of the heart and arteries with aging in a community-dwelling population

Cell-to-cell variation in gene expression and the aging process

Aging, stress, and senescence in plants: what can biological diversity teach us?

Are the 50's, the transition decade, in choroid plexus aging?

Sex differences in the contribution of different physiological systems to physical function in older adults

The impact of immuno-aging on SARS-CoV-2 vaccine development

Effects of sleep deprivation on endothelial function in adult humans: a systematic review

Alterations in the estrogen receptor profile of cardiovascular tissues during aging

Quest for a summary measure of biological age: the health and retirement study

Recent advances and future avenues in understanding the role of adipose tissue cross talk in mediating skeletal muscle mass and function with ageing

A novel role of the mitochondrial iron-sulfur cluster assembly protein ISCU-1/ISCU in longevity and stress response

Novel aspects of age-protection by spermidine supplementation are associated with preserved telomere length

Correction to: Hydrogen sulfide ameliorates aging-associated changes in the kidney

The relative contributions of behavioral, biological, and psychological risk factors in the association between psychosocial stress and all-cause mortality among middle- and older-aged adults in the USA

Heterochronic blood exchange attenuates age-related neuroinflammation and confers cognitive benefits: do microvascular protective effects play a role?

Level of the SARS-CoV-2 receptor ACE2 activity is highly elevated in old-aged patients with aortic stenosis: implications for ACE2 as a biomarker for the severity of COVID-19

Dynamics of leukocyte telomere length in adults aged 50 and older: a longitudinal population-based cohort study

Associations of muscle lipid content with physical function and resistance training outcomes in older adults: altered responses with metformin

Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock

Age-associated difference in circulating ACE2, the gateway for SARS-COV-2, in humans: results from the InCHIANTI study

Effects of 16 months of high intensity resistance training on thigh muscle fat infiltration in elderly men with osteosarcopenia

Cerebral hemodynamics in obesity: relationship with sex, age, and adipokines in a cohort-based study

Exogenous hydrogen sulfide and miR-21 antagonism attenuates macrophage-mediated inflammation in ischemia reperfusion injury of the aged kidney

SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome-the Myhre syndrome