Terkko Navigator / GeroScience

Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation

Senescent cell accumulation mechanisms inferred from parabiosis

Is impaired dopaminergic function associated with mobility capacity in older adults?

Thyroid hormone signaling is associated with physical performance, muscle mass, and strength in a cohort of oldest-old: results from the Mugello study

Biomarkers and phenotypic expression in Alzheimer's disease: exploring the contribution of frailty in the Alzheimer's Disease Neuroimaging Initiative

Characterization of the plasma proteomic profile of frailty phenotype

Plasma dilution improves cognition and attenuates neuroinflammation in old mice

Association between telomere length, frailty and death in older adults

Glycolytic inhibition: an effective strategy for developing calorie restriction mimetics

Comparison of clinical characteristics of patients with pandemic SARS-CoV-2-related and community-acquired pneumonias in Hungary - a pilot historical case-control study

Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging

I₂ imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway

Late-onset depression is associated to age-related central auditory processing disorder in an older population in Southern Italy

C₆₀ in olive oil causes light-dependent toxicity and does not extend lifespan in mice

Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling

"Cerebral small vessel disease and other influential factors of cognitive impairment in the middle-aged: a long-term observational cohort PURE-MIND study in Poland"

Quality of life after traumatic brain injury: a cross-sectional analysis uncovers age- and sex-related differences over the adult life span

Internalize at your peril: internalizing disorders as risk factors for dementia-cohort study

Primary neuron and astrocyte cultures from postnatal Callithrix jacchus: a non-human primate in vitro model for research in neuroscience, nervous system aging, and neurological diseases of aging

Longitudinal trends in master track and field performance throughout the aging process: 83,209 results from Sweden in 16 athletics disciplines

Effect of rapamycin on aging and age-related diseases-past and future

Association of physical activity and sedentary time with structural brain networks-The Maastricht Study

Association between genetically predicted telomere length and facial skin aging in the UK Biobank: a Mendelian randomization study

Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?

Imaging the role of blood-brain barrier disruption in normal cognitive ageing

High-resolution yeast quiescence profiling in human-like media reveals complex influences of auxotrophy and nutrient availability

Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis

Traumatic brain injury-induced cerebral microbleeds in the elderly

From bedside to battlefield: intersection of ketone body mechanisms in geroscience with military resilience

Diabetes medications as potential calorie restriction mimetics-a focus on the alpha-glucosidase inhibitor acarbose

Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss

Age-dependent modulation of bone metabolism in zebrafish scales as new model of male osteoporosis in lower vertebrates

The retention of fall-resisting behavior derived from treadmill slip-perturbation training in community-dwelling older adults

Protein signatures from blood plasma and urine suggest changes in vascular function and IL-12 signaling in elderly with a history of chronic diseases compared with an age-matched healthy cohort

Semiautomatic morphometric analysis of skeletal muscle obtained by needle biopsy in older adults

HIV-1 Tat promotes age-related cognitive, anxiety-like, and antinociceptive impairments in female mice that are moderated by aging and endocrine status

Mitochondrial-derived peptides in aging and age-related diseases

Estrogen receptor involvement in vascular cognitive impairment and vascular dementia pathogenesis and treatment

A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin

Correction to: Reflections on designing population surveys for COVID-19 infection and prevalence

A multivariate model of time to conversion from mild cognitive impairment to Alzheimer's disease

Amyloidosis increase is not attenuated by long-term calorie restriction or related to neuron density in the prefrontal cortex of extremely aged rhesus macaques

A short digital eye-tracking assessment predicts cognitive status among adults

The gut microbiome-derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging

Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging

Treatment with a DC-SIGN ligand reduces macrophage polarization and diastolic dysfunction in the aging female but not male mouse hearts

Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease

Handgrip strength-a risk indicator for future fractures in the general population: findings from a prospective study and meta-analysis of 19 prospective cohort studies

Reflections on designing population surveys for COVID-19 infection and prevalence

Association of inflammatory mediators with frailty status in older adults: results from a systematic review and meta-analysis