Terkko Navigator / Genome Research

Exome-wide assessment of the functional impact and pathogenicity of multinucleotide mutations [RESEARCH]

Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging [RESEARCH]

Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer [RESEARCH]

Histone methyltransferase PRDM9 is not essential for meiosis in male mice [RESEARCH]

Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features [RESEARCH]

Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish [RESEARCH]

Haploid selection drives new gene male germline expression [RESEARCH]

Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork [RESEARCH]

A machine-learning approach for accurate detection of copy number variants from exome sequencing [METHOD]

Genetic variant pathogenicity prediction trained using disease-specific clinical sequencing data sets [METHOD]

OMA standalone: orthology inference among public and custom genomes and transcriptomes [METHOD]

Crunch: integrated processing and modeling of ChIP-seq data in terms of regulatory motifs [METHOD]

Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome [RESOURCES]

Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns [RESOURCES]

Pervasive and dynamic transcription initiation in Saccharomyces cerevisiae [RESOURCES]

Sydney Brenner--a personal perspective [IN MEMORIAM]

4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in facioscapulohumeral muscular dystrophy [RESEARCH]

A massively parallel 3' UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization [RESEARCH]

Systems analysis reveals complex biological processes during virus infection fate decisions [RESEARCH]

Diversification and collapse of a telomere elongation mechanism [RESEARCH]

Turnover of ribosome-associated transcripts from de novo ORFs produces gene-like characteristics available for de novo gene emergence in wild yeast populations [RESEARCH]

Convergent recombination cessation between mating-type genes and centromeres in selfing anther-smut fungi [RESEARCH]

Human contamination in bacterial genomes has created thousands of spurious proteins [RESEARCH]

Plasmid detection and assembly in genomic and metagenomic data sets [METHOD]

methyl-ATAC-seq measures DNA methylation at accessible chromatin [METHOD]

One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry [METHOD]

Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes [METHOD]

Beta-binomial modeling of CRISPR pooled screen data identifies target genes with greater sensitivity and fewer false negatives [METHOD]

Recompleting the Caenorhabditis elegans genome [RESOURCES]

Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans [RESOURCES]

The C. elegans embryonic transcriptome with tissue, time, and alternative splicing resolution [RESOURCES]

Interplay between coding and exonic splicing regulatory sequences [RESEARCH]

Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its precancerous precursor state [RESEARCH]

Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin [RESEARCH]

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries [RESEARCH]

Brown rat demography reveals pre-commensal structure in eastern Asia before expansion into Southeast Asia [RESEARCH]

ATAC-seq reveals regional differences in enhancer accessibility during the establishment of spatial coordinates in the Drosophila blastoderm [RESEARCH]

Differences in firing efficiency, chromatin, and transcription underlie the developmental plasticity of the Arabidopsis DNA replication origins [RESEARCH]

Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly [METHOD]

A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS [METHOD]

A virome-wide clonal integration analysis platform for discovering cancer viral etiology [METHOD]

Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid [METHOD]

Accurate analysis of genuine CRISPR editing events with ampliCan [METHOD]

Analysis of 100 high-coverage genomes from a pedigreed captive baboon colony [RESOURCES]

The accessible chromatin landscape of the murine hippocampus at single-cell resolution [RESOURCES]

Structural variants in 3000 rice genomes [RESOURCES]

Erratum: Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus [ERRATUM]

Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans [RESEARCH]

Coexpression patterns define epigenetic regulators associated with neurological dysfunction [RESEARCH]

New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulation [RESEARCH]