Terkko Navigator / Genome Research

Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease [RESEARCH]

Allele-specific alternative splicing and its functional genetic variants in human tissues [RESEARCH]

Fixation of allelic gene expression landscapes and expression bias pattern shape the transcriptome of the clonal Amazon molly [RESEARCH]

Evolution of genome structure in the Drosophila simulans species complex [RESEARCH]

Topologically associating domains and their role in the evolution of genome structure and function in Drosophila [RESEARCH]

Sir3 mediates long-range chromosome interactions in budding yeast [RESEARCH]

Rtt109 slows replication speed by histone N-terminal acetylation [RESEARCH]

Abundantly expressed class of noncoding RNAs conserved through the multicellular evolution of dictyostelid social amoebas [RESEARCH]

Accurate and efficient detection of gene fusions from RNA sequencing data [METHOD]

Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs [METHOD]

A minimally destructive protocol for DNA extraction from ancient teeth [METHOD]

Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognition [RESOURCES]

A new emu genome illuminates the evolution of genome configuration and nuclear architecture of avian chromosomes [RESOURCES]

A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons [RESOURCES]

Post-transcriptional circadian regulation in macrophages organizes temporally distinct immunometabolic states [RESEARCH]

KDM1A maintains genome-wide homeostasis of transcriptional enhancers [RESEARCH]

Dosage-sensitive functions in embryonic development drove the survival of genes on sex-specific chromosomes in snakes, birds, and mammals [RESEARCH]

Cis-acting variation is common across regulatory layers but is often buffered during embryonic development [RESEARCH]

Genome and time-of-day transcriptome of Wolffia australiana link morphological minimization with gene loss and less growth control [RESEARCH]

Transporter genes in biosynthetic gene clusters predict metabolite characteristics and siderophore activity [RESEARCH]

TSA-seq reveals a largely conserved genome organization relative to nuclear speckles with small position changes tightly correlated with gene expression changes [METHOD]

Evidence of widespread, independent sequence signature for transcription factor cobinding [METHOD]

Epigenomic differences in the human and chimpanzee genomes are associated with structural variation [METHOD]

Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution [METHOD]

Effects of transcriptional noise on estimates of gene and transcript expression in RNA sequencing experiments [METHOD]

Contamination detection in sequencing studies using the mitochondrial phylogeny [METHOD]

Genome-wide prediction of DNA mutation effect on nucleosome positions for yeast synthetic genomics [METHOD]

A platform for curated products from novel open reading frames prompts reinterpretation of disease variants [RESOURCES]

Modeling molecular development of breast cancer in canine mammary tumors [RESOURCES]

Data structures based on k-mers for querying large collections of sequencing data sets [REVIEW]

Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis [RESEARCH]

Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development [RESEARCH]

Thermal stress accelerates Arabidopsis thaliana mutation rate [RESEARCH]

The origin and evolution of a distinct mechanism of transcription initiation in yeasts [RESEARCH]

Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules [RESEARCH]

DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution [METHOD]

Transcript assembly improves expression quantification of transposable elements in single-cell RNA-seq data [METHOD]

Predictive modeling of single-cell DNA methylome data enhances integration with transcriptome data [METHOD]

Greater strength of selection and higher proportion of beneficial amino acid changing mutations in humans compared with mice and Drosophila melanogaster [METHOD]

Generation of mouse conditional knockout alleles in one step using the i-GONAD method [METHOD]

MAnorm2 for quantitatively comparing groups of ChIP-seq samples [METHOD]

Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders [RESOURCES]

Accessing NCBI data using the NCBI Sequence Viewer and Genome Data Viewer (GDV) [RESOURCES]

Complex mosaic structural variations in human fetal brains [RESEARCH]

Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains [RESEARCH]

Sequence analysis in Bos taurus reveals pervasiveness of X-Y arms races in mammalian lineages [RESEARCH]

Tissue-specific patterns of regulatory changes underlying gene expression differences among Ficedula flycatchers and their naturally occurring F1 hybrids [RESEARCH]

Loss of histone H3.3 results in DNA replication defects and altered origin dynamics in C. elegans [RESEARCH]

Distinctive regulatory architectures of germline-active and somatic genes in C. elegans [RESEARCH]

Global regulatory features of alternative splicing across tissues and within the nervous system of C. elegans [RESEARCH]