Terkko Navigator / Genome Research

Decrypting noncoding RNA interactions, structures, and functional networks [PERSPECTIVE]

The 22q11 low copy repeats are characterized by unprecedented size and structural variability [RESEARCH]

Genome-wide analysis of polymerase III-transcribed Alu elements suggests cell-type-specific enhancer function [RESEARCH]

Replication timing networks reveal a link between transcription regulatory circuits and replication timing control [RESEARCH]

Estrogen-independent molecular actions of mutant estrogen receptor 1 in endometrial cancer [RESEARCH]

Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance [RESEARCH]

A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing [RESEARCH]

Distinct types of short open reading frames are translated in plant cells [RESEARCH]

Unique genetic basis of the distinct antibiotic potency of high acetic acid production in the probiotic yeast Saccharomyces cerevisiae var. boulardii [RESEARCH]

Large-scale genome analysis of bovine commensal Escherichia coli reveals that bovine-adapted E. coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strains [RESEARCH]

Identifying loci under positive selection in complex population histories [METHOD]

Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing [METHOD]

Discovering human transcription factor physical interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays [METHOD]

Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis [METHOD]

Pediatric Cancer Variant Pathogenicity Information Exchange (PeCanPIE): a cloud-based platform for curating and classifying germline variants [RESOURCES]

Corrigendum: A long-term demasculinization of X-linked intergenic noncoding RNAs in Drosophila melanogaster [CORRIGENDA]

Corrigendum: Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers [CORRIGENDA]

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma [RESEARCH]

Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome [RESEARCH]

Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin [RESEARCH]

Whole-genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes [RESEARCH]

Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations [RESEARCH]

Capture of a functionally active methyl-CpG binding domain by an arthropod retrotransposon family [RESEARCH]

Characterization of functional relationships of R-loops with gene transcription and epigenetic modifications in rice [RESEARCH]

Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites [RESEARCH]

Estimation of allele-specific fitness effects across human protein-coding sequences and implications for disease [METHOD]

Efficient and flexible tagging of endogenous genes by homology-independent intron targeting [METHOD]

Single-molecule long-read sequencing reveals the chromatin basis of gene expression [METHOD]

A novel synthetic-genetic-array-based yeast one-hybrid system for high discovery rate and short processing time [METHOD]

BiosyntheticSPAdes: reconstructing biosynthetic gene clusters from assembly graphs [METHOD]

Benchmark and integration of resources for the estimation of human transcription factor activities [RESOURCES]

Exome-wide assessment of the functional impact and pathogenicity of multinucleotide mutations [RESEARCH]

Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging [RESEARCH]

Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer [RESEARCH]

Histone methyltransferase PRDM9 is not essential for meiosis in male mice [RESEARCH]

Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features [RESEARCH]

Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish [RESEARCH]

Haploid selection drives new gene male germline expression [RESEARCH]

Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork [RESEARCH]

A machine-learning approach for accurate detection of copy number variants from exome sequencing [METHOD]

Genetic variant pathogenicity prediction trained using disease-specific clinical sequencing data sets [METHOD]

OMA standalone: orthology inference among public and custom genomes and transcriptomes [METHOD]

Crunch: integrated processing and modeling of ChIP-seq data in terms of regulatory motifs [METHOD]

Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome [RESOURCES]

Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns [RESOURCES]

Pervasive and dynamic transcription initiation in Saccharomyces cerevisiae [RESOURCES]

Sydney Brenner--a personal perspective [IN MEMORIAM]

4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in facioscapulohumeral muscular dystrophy [RESEARCH]

A massively parallel 3' UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization [RESEARCH]

Systems analysis reveals complex biological processes during virus infection fate decisions [RESEARCH]