Terkko Navigator / Genome Research

Interplay between coding and exonic splicing regulatory sequences [RESEARCH]

Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its precancerous precursor state [RESEARCH]

Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin [RESEARCH]

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries [RESEARCH]

Brown rat demography reveals pre-commensal structure in eastern Asia before expansion into Southeast Asia [RESEARCH]

ATAC-seq reveals regional differences in enhancer accessibility during the establishment of spatial coordinates in the Drosophila blastoderm [RESEARCH]

Differences in firing efficiency, chromatin, and transcription underlie the developmental plasticity of the Arabidopsis DNA replication origins [RESEARCH]

Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly [METHOD]

A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS [METHOD]

A virome-wide clonal integration analysis platform for discovering cancer viral etiology [METHOD]

Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid [METHOD]

Accurate analysis of genuine CRISPR editing events with ampliCan [METHOD]

Analysis of 100 high-coverage genomes from a pedigreed captive baboon colony [RESOURCES]

The accessible chromatin landscape of the murine hippocampus at single-cell resolution [RESOURCES]

Structural variants in 3000 rice genomes [RESOURCES]

Erratum: Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus [ERRATUM]

Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans [RESEARCH]

Coexpression patterns define epigenetic regulators associated with neurological dysfunction [RESEARCH]

New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulation [RESEARCH]

CG dinucleotides enhance promoter activity independent of DNA methylation [RESEARCH]

TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells [RESEARCH]

Evolution of gene regulation in ruminants differs between evolutionary breakpoint regions and homologous synteny blocks [RESEARCH]

The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes [RESEARCH]

Cohesin occupancy and composition at enhancers and promoters are linked to DNA replication origin proximity in Drosophila [RESEARCH]

Chromatin architecture reorganization during neuronal cell differentiation in Drosophila genome [RESEARCH]

Detection of vancomycin-resistant Enterococcus faecium hospital-adapted lineages in municipal wastewater treatment plants indicates widespread distribution and release into the environment [RESEARCH]

Resolving the full spectrum of human genome variation using Linked-Reads [METHOD]

Long-read single-molecule maps of the functional methylome [METHOD]

Identification of human silencers by correlating cross-tissue epigenetic profiles and gene expression [METHOD]

Improved discovery of genetic interactions using CRISPRiSeq across multiple environments [METHOD]

GenTree, an integrated resource for analyzing the evolution and function of primate-specific coding genes [RESOURCES]

Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses [RESOURCES]

Corrigendum: Initiation of mtDNA transcription is followed by pausing, and diverges across human cell types and during evolution [CORRIGENDUM]

Corrigendum: H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells [CORRIGENDUM]

Ribosomal DNA harbors an evolutionarily conserved clock of biological aging [RESEARCH]

Most chromatin interactions are not in linkage disequilibrium [RESEARCH]

High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity [RESEARCH]

The circular RNome of primary breast cancer [RESEARCH]

Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion [RESEARCH]

Pou5f3, SoxB1, and Nanog remodel chromatin on high nucleosome affinity regions at zygotic genome activation [RESEARCH]

Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species-dependent essential genes [RESEARCH]

Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination [RESEARCH]

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin [METHOD]

Bayesian-based noninvasive prenatal diagnosis of single-gene disorders [METHOD]

Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes [METHOD]

Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells [METHOD]

JACKS: joint analysis of CRISPR/Cas9 knockout screens [METHOD]

Comprehensive, integrated, and phased whole-genome analysis of the primary ENCODE cell line K562 [RESOURCES]

PepQuery enables fast, accurate, and convenient proteomic validation of novel genomic alterations [RESOURCES]

Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis [RESOURCES]