Terkko Navigator / Genes and Development

Beyond rRNA and snRNA: tRNA as a 2'-O-methylation target for nucleolar and Cajal body box C/D RNPs [Outlook]

Cooperative 2'-O-methylation of the wobble cytidine of human elongator tRNAMet(CAT) by a nucleolar and a Cajal body-specific box C/D RNP [Research Communications]

Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism [Research Papers]

Chromatin restriction by the nucleosome remodeler Mi-2{beta} and functional interplay with lineage-specific transcription regulators control B-cell differentiation [Research Papers]

GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells [Research Papers]

Phase separation of Polycomb-repressive complex 1 is governed by a charged disordered region of CBX2 [Research Papers]

Clustered telomeres in phase-separated nuclear condensates engage mitotic DNA synthesis through BLM and RAD52 [Research Papers]

Dedifferentiation by adenovirus E1A due to inactivation of Hippo pathway effectors YAP and TAZ [Research Papers]

Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery [Research Papers]

PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability [Research Papers]

Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors [Research Papers]

Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer [Reviews]

Role of tumor and host autophagy in cancer metabolism [Reviews]

Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase [Research Communications]

Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding [Research Papers]

ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis [Research Papers]

The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration [Research Papers]

The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells [Research Papers]

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks [Research Papers]

Ccr4-Not maintains genomic integrity by controlling the ubiquitylation and degradation of arrested RNAPII [Research Papers]

Structural basis for inhibition of a response regulator of {sigma}S stability by a ClpXP antiadaptor [Research Papers]

Corrigendum: TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency [Corrigendum]

Retraction: Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos [Retraction]

HES1, two programs: promoting the quiescence and proliferation of adult neural stem cells [Outlook]

The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation [Research Papers]

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells [Research Papers]

High Hes1 expression and resultant Ascl1 suppression regulate quiescent vs. active neural stem cells in the adult mouse brain [Research Papers]

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells [Research Papers]

NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction [Research Papers]

The Set1 complex is dimeric and acts with Jhd2 demethylation to convey symmetrical H3K4 trimethylation [Research Papers]

Transcriptional gene silencing requires dedicated interaction between HP1 protein Chp2 and chromatin remodeler Mit1 [Research Papers]

In vitro analysis of RNA polymerase II elongation complex dynamics [Research Papers]

Corrigendum: 'Building a perfect body: control of vertebrate organogenesis by PBX-dependent regulatory networks [Corrigendum]

Phasing in heterochromatin during development [Perspectives]

Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula [Research Communications]

TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth [Research Papers]

Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila [Research Papers]

CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability [Research Papers]

Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression [Research Papers]

The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise [Research Papers]

Auxin regulates endosperm cellularization in Arabidopsis [Research Papers]

Corrigendum: Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome [Corrigendum]

Help from my friends--cooperation of BMAL1 with noncircadian transcription factors [Outlook]

'Building a perfect body: control of vertebrate organogenesis by PBX-dependent regulatory networks [Reviews]

Resolution of human ribosomal DNA occurs in anaphase, dependent on tankyrase 1, condensin II, and topoisomerase II{alpha} [Research Communications]

DNA polymerase {theta} accomplishes translesion synthesis opposite 1,N6-ethenodeoxyadenosine with a remarkably high fidelity in human cells [Research Communications]

Sfp1 regulates transcriptional networks driving cell growth and division through multiple promoter-binding modes [Research Communications]

Tissue-specific BMAL1 cistromes reveal that rhythmic transcription is associated with rhythmic enhancer-enhancer interactions [Research Papers]

BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma [Research Papers]

The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms [Research Papers]