Terkko Navigator / Genes and Development

Enhancers, gene regulation, and genome organization [Meeting Reviews]

Mutant p53 in cell-cell interactions [Reviews]

Interorganelle communication, aging, and neurodegeneration [Reviews]

Genetic basis of chemical communication in eusocial insects [Reviews]

Human nucleoli comprise multiple constrained territories, tethered to individual chromosomes [Research Communications]

Identification and characterization of conserved noncoding cis-regulatory elements that impact Mecp2 expression and neurological functions [Research Communications]

WWTR1(TAZ)-CAMTA1 reprograms endothelial cells to drive epithelioid hemangioendothelioma [Research Papers]

WWTR1(TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis [Research Papers]

Mutant p53 regulates Survivin to foster lung metastasis [Research Papers]

Fine-tuning p53 activity by modulating the interaction between eukaryotic translation initiation factor eIF4E and RNA-binding protein RBM38 [Research Papers]

RAD21 is a driver of chromosome 8 gain in Ewing sarcoma to mitigate replication stress [Research Papers]

Corrigendum: UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide [Errata]

Getting under the skin of Polycomb-dependent gene regulation [Outlook]

Peripheral clocks tick independently of their master [Outlook]

Chronic tissue inflammation and metabolic disease [Reviews]

Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocks [Research Communications]

BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex [Research Papers]

Polycomb complexes redundantly maintain epidermal stem cell identity during development [Research Papers]

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver [Research Papers]

XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence [Research Papers]

Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex [Research Papers]

Early behavioral and molecular events leading to caste switching in the ant Harpegnathos [Research Papers]

Erratum: A role for alternative splicing in circadian control of exocytosis and glucose homeostasis [Errata]

Learning from the worm: the effectiveness of protein-bound Moco to treat Moco deficiency [Outlook]

Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function [Reviews]

Dietary interventions as regulators of stem cell behavior in homeostasis and disease [Reviews]

Protein-bound molybdenum cofactor is bioavailable and rescues molybdenum cofactor-deficient C. elegans [Research Communications]

ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer [Research Papers]

SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic {beta} cells [Research Papers]

An interplay of NOX1-derived ROS and oxygen determines the spermatogonial stem cell self-renewal efficiency under hypoxia [Research Papers]

Esc2 orchestrates substrate-specific sumoylation by acting as a SUMO E2 cofactor in genome maintenance [Research Papers]

Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression [Research Papers]

Substrate-dependent effects of quaternary structure on RNase E activity [Research Papers]

Corrigendum: mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression [Errata]

The end protection problem--an unexpected twist in the tail [Perspectives]

TFs for TEs: the transcription factor repertoire of mammalian transposable elements [Reviews]

The missing linker: emerging trends for H1 variant-specific functions [Reviews]

mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression [Research Communications]

Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization [Research Papers]

Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression [Research Papers]

The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma [Research Papers]

Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice [Research Papers]

A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21 [Research Papers]

Pioneer-like factor GAF cooperates with PBAP (SWI/SNF) and NURF (ISWI) to regulate transcription [Research Papers]

Conserved Gsx2/Ind homeodomain monomer versus homodimer DNA binding defines regulatory outcomes in flies and mice [Research Papers]

Corrigendum: Molecular mechanism for the interaction between human CPSF30 and hFip1 [Errata]

A window in time for {beta}-cell regeneration [Outlook]

A new role for the synaptonemal complex in the regulation of meiotic recombination [Outlook]

Senescence and the SASP: many therapeutic avenues [Reviews]

Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities [Reviews]