Terkko Navigator / Genes and Development

HES1, two programs: promoting the quiescence and proliferation of adult neural stem cells [Outlook]

The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation [Research Papers]

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells [Research Papers]

High Hes1 expression and resultant Ascl1 suppression regulate quiescent vs. active neural stem cells in the adult mouse brain [Research Papers]

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells [Research Papers]

NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction [Research Papers]

The Set1 complex is dimeric and acts with Jhd2 demethylation to convey symmetrical H3K4 trimethylation [Research Papers]

Transcriptional gene silencing requires dedicated interaction between HP1 protein Chp2 and chromatin remodeler Mit1 [Research Papers]

In vitro analysis of RNA polymerase II elongation complex dynamics [Research Papers]

Corrigendum: 'Building a perfect body: control of vertebrate organogenesis by PBX-dependent regulatory networks [Corrigendum]

Phasing in heterochromatin during development [Perspectives]

Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula [Research Communications]

TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth [Research Papers]

Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila [Research Papers]

CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability [Research Papers]

Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression [Research Papers]

The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise [Research Papers]

Auxin regulates endosperm cellularization in Arabidopsis [Research Papers]

Corrigendum: Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome [Corrigendum]

Help from my friends--cooperation of BMAL1 with noncircadian transcription factors [Outlook]

'Building a perfect body: control of vertebrate organogenesis by PBX-dependent regulatory networks [Reviews]

Resolution of human ribosomal DNA occurs in anaphase, dependent on tankyrase 1, condensin II, and topoisomerase II{alpha} [Research Communications]

DNA polymerase {theta} accomplishes translesion synthesis opposite 1,N6-ethenodeoxyadenosine with a remarkably high fidelity in human cells [Research Communications]

Sfp1 regulates transcriptional networks driving cell growth and division through multiple promoter-binding modes [Research Communications]

Tissue-specific BMAL1 cistromes reveal that rhythmic transcription is associated with rhythmic enhancer-enhancer interactions [Research Papers]

BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma [Research Papers]

The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms [Research Papers]

RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena [Research Papers]

Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity [Research Papers]

Corrigendum: LMI1 homeodomain protein regulates organ proportions by spatial modulation of endoreduplication [Corrigendum]

Corrigendum: Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability [Corrigendum]

Short-term gain, long-term pain: the senescence life cycle and cancer [Reviews]

Nuclear pore density controls heterochromatin reorganization during senescence [Research Communications]

Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis [Research Papers]

CD44 splice isoform switching determines breast cancer stem cell state [Research Papers]

Afadin cooperates with Claudin-2 to promote breast cancer metastasis [Research Papers]

Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program [Research Papers]

A ZNRF3-dependent Wnt/{beta}-catenin signaling gradient is required for adrenal homeostasis [Research Papers]

RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening [Research Papers]

A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex [Research Papers]

Erratum: Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination [Errata]

Evolving imprinting control regions: KRAB zinc fingers hold the key [Outlook]

Is it time to take R(epressive) out of PRC1? [Outlook]

Helix-loop-helix proteins and the advent of cellular diversity: 30 years of discovery [Reviews]

Molecular regulation of peripheral B cells and their progeny in immunity [Reviews]

ZNF445 is a primary regulator of genomic imprinting [Research Communications]

PRC1 preserves epidermal tissue integrity independently of PRC2 [Research Communications]

Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia [Research Papers]

Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination [Research Papers]

The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans [Research Papers]