Terkko Navigator / Gene Therapy

AAVrh-10 transduces outer retinal cells in rodents and rabbits following intravitreal administration

Inferring novel genes related to colorectal cancer via random walk with restart algorithm

Beyond cystic fibrosis transmembrane conductance regulator therapy: a perspective on gene therapy and small molecule treatment for cystic fibrosis

Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA

Gene therapy of hematological disorders: current challenges

A next-generation sequencing method for gene doping detection that distinguishes low levels of plasmid DNA against a background of genomic DNA

Gene therapy for refractory angina and cell therapy for heart failure: experience of a Brazilian research group

Genetic therapies, human genetic enhancement, and … eugenics?

Design and applications of gene therapy vectors for mucopolysaccharidosis in Colombia

Effects of a combinatorial treatment with gene and cell therapy on retinal ganglion cell survival and axonal outgrowth after optic nerve injury

AAV9 Vector: a Novel modality in gene therapy for spinal muscular atrophy

Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells

Bringing balance to the force–regulatable gene therapy for epilepsy

Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors

AAV-encoded CaV2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain

Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies

Delivering cellular and gene therapies to patients: solutions for realizing the potential of the next generation of medicine

Reviewer recognition

Cell therapy for Parkinson′s disease is coming of age: current challenges and future prospects with a focus on immunomodulation

Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury

Polarized AAVR expression determines infectivity by AAV gene therapy vectors

Regulated ex vivo regional gene therapy for bone repair using an inducible caspase-9 suicide gene system

Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus

Magic realism: a Latin American paradigm for stem cell research & development?

Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritis

Stability of the adeno-associated virus 8 reference standard material

Combination of cabazitaxel and p53 gene therapy abolishes prostate carcinoma tumor growth

Safe and neuroprotective vectors for long-term traumatic brain injury gene therapy

A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases

A novel approach for assessment of prostate cancer aggressiveness using survivin-driven tumour-activatable minicircles

Combination of cytokine-enhanced vaccine and chemo-gene therapy as surgery adjuvant treatments for spontaneous canine melanoma

Gene and cell therapy on the acquisition and relapse-like binge drinking in a model of alcoholism: translational options

ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling

scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor

Regulatable adenovector harboring the GFP and Yamanaka genes for implementing regenerative medicine in the brain

Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming

Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

Factors governing the transduction efficiency of adeno-associated virus in the retinal ganglion cells following intravitreal injection

Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics

Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression

Production of lentiviral vectors using novel, enzymatically produced, linear DNA

Correction: Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials

Comparative efficacy of dermal fibroblast-mediated and direct adenoviral bone morphogenetic protein-2 gene therapy for bone regeneration in an equine rib model

Gene therapy progress and prospects: synthetic polymer-based systems

The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation

Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome

Expression and maturation of Sendai virus vector-derived CFTR protein: functional and biochemical evidence using a GFP-CFTR fusion protein

Topical matrix-based siRNA silences local gene expression in a murine wound model

Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection

Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma