Terkko Navigator / Gene Therapy

Development of a dual hybrid AAV vector for endothelial-targeted expression of von Willebrand factor

Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates

Double viral vector technology for selective manipulation of neural pathways with higher level of efficiency and safety

Correction: Conditional replication of oncolytic viruses based on detection of oncogenic mRNA

FEN1 inhibitor synergizes with low-dose camptothecin to induce increased cell killing via the mitochondria mediated apoptotic pathway

Restored microRNA-519a enhances the radiosensitivity of non-small cell lung cancer via suppressing EphA2

Gene editing and RNAi approaches for COVID-19 diagnostics and therapeutics

Host antibacterial defense of 6–10 Gy γ-irradiated mice subjected to lentiviral vector-based Gas5 gene therapy

Site-specific modifications to AAV8 capsid yields enhanced brain transduction in the neonatal MPS IIIB mouse

Effects of oncolytic viruses and viral vectors on immunity in glioblastoma

Molecular targeting of vulnerable RNA sequences in SARS CoV-2: identifying clinical feasibility

Antitumor effects of IL-12 and GM-CSF co-expressed in an engineered oncolytic HSV-1

Sensitization of ON-bipolar cells with ambient light activatable multi-characteristic opsin rescues vision in mice

Self-amplifying RNA vaccines for infectious diseases

Intra-cisterna magna delivery of an AAV vector with the GLUT1 promoter in a pig recapitulates the physiological expression of SLC2A1

Long noncoding RNA CA3-AS1 suppresses gastric cancer migration and invasion by sponging miR-93-5p and targeting BTG3

Comparative efficacy of dermal fibroblast-mediated and direct adenoviral bone morphogenetic protein-2 gene therapy for bone regeneration in an equine rib model

Gene therapy progress and prospects: synthetic polymer-based systems

The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation

Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome

Expression and maturation of Sendai virus vector-derived CFTR protein: functional and biochemical evidence using a GFP-CFTR fusion protein

Topical matrix-based siRNA silences local gene expression in a murine wound model

Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection

Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma

Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation

In vivo gene silencing in solid tumors by targeted electrically mediated siRNA delivery