Terkko Navigator / Gahmberg, C.G. (UH Viikki Campus)

Regulation of cell adhesion: a collaborative effort of integrins, their ligands, cytoplasmic actors, and phosphorylation

Phosphorylation of theα-chain in the integrin LFA-1 enables β2-chain phosphorylation and α-actinin binding required for cell adhesion

Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia

Mitochondrial toxicity of triclosan on mammalian cells

LFA-1 integrin antibodies inhibit leukocyteα4β1-mediated adhesion by intracellular signaling

RIFINs are adhesins implicated in severe Plasmodium falciparum malaria

The peptide toxin amylosin of Bacillus amyloliquefaciens from moisture-damaged buildings is immunotoxic, induces potassium efflux from mammalian cells, and has antimicrobial activity

ICAM-5 affects spine maturation by regulation of NMDA receptor binding toα-actinin

ICAM-5: a neuronal dendritic adhesion molecule involved in immune and neuronal functions

Specific phosphorylations transmit signals from leukocyteβ2 to β1 integrins and regulate adhesion

Regulation of integrin activity by phosphorylation

Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions

Interactions between intercellular adhesion molecule-5 positive elements and their surroundings in the rodent visual cortex

Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin

SHARPIN regulates uropod detachment in migrating lymphocytes

Integrin CD11c/CD18α-chain phosphorylation is functionally important

In vivo targeting of activated leukocytes by aβ2-integrin binding peptide

Subcellular localization of intercellular adhesion molecule-5 (telencephalin) in the visual cortex is not developmentally regulated in the absence of matrix metalloproteinase-9

Potato crop as a source of emetic Bacillus cereus and cereulide-induced mammalian cell toxicity

Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease

Interactions between ICAM-5 andβ1 integrins regulate neuronal synapse formation

Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots

TCR-induced activation of LFA-1 involves signaling through Tiam1

Hydrophobic interaction between the SH2 domain and the kinase domain is required for the activation of Csk

Role of leukemia cell invadosome in extramedullary infiltration

PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells

Introduction to recent advances in biochemistry, biophysics and molecular and cell biology

Regulation of integrin activity and signalling

Neuronal regulation of immune responses in the central nervous system

Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment

An unusual allosteric mobility of the C-terminal helix of a high-affinity alphaL integrin I domain variant bound to ICAM-5

Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding

ICAM-5--a novel two-facetted adhesion molecule in the mammalian brain

Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins

Shedded neuronal ICAM-5 suppresses T-cell activation

Importance of molecular studies on major blood groups--intercellular adhesion molecule-4, a blood group antigen involved in multiple cellular interactions

Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage

14-3-3 proteins bind both filamin and alphaLbeta2 integrin in activated T cells

A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin

DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues

Phosphorylation of the LFA-1 integrin beta2-chain on Thr-758 leads to adhesion, Rac-1/Cdc42 activation, and stimulation of CD69 expression in human T cells

Interfering with leukocyte integrin activation--a novel concept in the development of anti-inflammatory drugs

Red-cell ICAM-4 is a ligand for the monocyte/macrophage integrin CD11c/CD18: characterization of the binding sites on ICAM-4

P-selectin glycoprotein ligand 1 and beta2-integrins cooperate in the adhesion of leukocytes to von Willebrand factor

alpha-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation

alpha-Actinin-dependent cytoskeletal anchorage is important for ICAM-5-mediated neuritic outgrowth

Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin

Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms

A tripeptide mimetic of von Willebrand factor residues 981-983 enhances platelet adhesion to fibrinogen by signaling through integrin alpha(IIb)beta3

Targeted anticancer drugs and their development