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The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analysesRegulatory toxicology and pharmacology11 dayssaveRefWorksSFX Info
Considerations when deriving compound-specific limits for extractables and leachables from pharmaceutical products: Four case studiesRegulatory toxicology and pharmacology14 dayssaveRefWorksSFX Info
Facilitation of risk assessment with evidence-based methods – A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertaintyRegulatory toxicology and pharmacology20 dayssaveRefWorksSFX Info
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophenRegulatory toxicology and pharmacology20 dayssaveRefWorksSFX Info
Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materialsRegulatory toxicology and pharmacology26 dayssaveRefWorksSFX Info
A review of clinical pharmacology deficiencies of European centralised drug marketing authorisation applicationsRegulatory toxicology and pharmacology33 dayssaveRefWorksSFX Info
Assessment of veterinary drug residues in food: Considerations when dealing with sub-optimal dataRegulatory toxicology and pharmacology41 dayssaveRefWorksSFX Info
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicalsRegulatory toxicology and pharmacology45 dayssaveRefWorksSFX Info
Toxicological risk assessment of bisphenol a released from dialyzers under simulated-use and exaggerated extraction conditionsRegulatory toxicology and pharmacology45 dayssaveRefWorksSFX Info
Safety of medicinal comfrey cream preparations (Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skinRegulatory toxicology and pharmacology49 dayssaveRefWorksSFX Info
Acute and sub-chronic toxicity studies of Benincasa hispida (Thunb.) cogniaux fruit extract in rodentsRegulatory toxicology and pharmacology58 dayssaveRefWorksSFX Info
Read-across can increase confidence in the Next Generation Risk Assessment for skin sensitisation: A case study with resorcinolRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Iraqi regulatory authority current system and experience with biosimilarsRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Building confidence in skin sensitisation potency assessment using new approach methodologies: report of the 3rd EPAA Partners Forum, Brussels, 28th October 2019Regulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
A toxicological evaluation of monomethylsilanetriol (MMST) stabilized in acacia gum, a novel silicon preparationRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Use of mechanistic information to derive chemical-specific adjustment factors – Refinement of risk assessmentRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
DP-2Ø2216-6 maize does not adversely affect rats in a 90-day feeding studyRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Safety testing of adult novelties using in vitro methodsRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
A 26-week toxicological study of Xuezhikang (XZK), red yeast rice extract, in Beagle dogs with a 4-week recovery periodRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Four-week repeated dose oral toxicity study of KDS2010, a novel selective monoamine oxidase B inhibitor, in Sprague Dawley ratsRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Effects of an ethanolic extract and fractions from Piper glabratum (Piperaceae) leaves on pain and inflammationRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Development of peptide therapeutics: A nonclinical safety assessment perspectiveRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Reflections on the OECD guidelines for in vitro skin absorption studiesRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Nonclinical safety assessment of epigenetic modulatory drugs: Current status and industry perspectiveRegulatory toxicology and pharmacology77 dayssaveRefWorksSFX Info
Can we define a level of protection for allergic consumers that everyone can accept?Regulatory toxicology and pharmacology82 dayssaveRefWorksSFX Info
Copper alloys’ metal migration and bioaccessibility in saliva and gastric fluidRegulatory toxicology and pharmacology82 dayssaveRefWorksSFX Info
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendationsRegulatory toxicology and pharmacology92 dayssaveRefWorksSFX Info
Evaluation of chronic toxicity of cyclocreatine, a creatine analog, in Sprague Dawley rat after oral gavage administration for up to 26 weeksRegulatory toxicology and pharmacology94 dayssaveRefWorksSFX Info
Selecting a minimal set of androgen receptor assays for screening chemicalsRegulatory toxicology and pharmacology94 dayssaveRefWorksSFX Info
Dose-response assessment for impaired memory from chronic exposure to domoic acid among native American consumers of razor clamsRegulatory toxicology and pharmacology100 dayssaveRefWorksSFX Info
“New statistics” in regulatory toxicology?Regulatory toxicology and pharmacology100 dayssaveRefWorksSFX Info
Me-too validation study for in vitro skin irritation test with a reconstructed human epidermis model, KeraSkin™ for OECD test guideline 439Regulatory toxicology and pharmacology101 dayssaveRefWorksSFX Info
Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in miceRegulatory toxicology and pharmacology116 dayssaveRefWorksSFX Info
Use of the kinetically-derived maximum dose: Opportunities for delivering 3Rs benefitsRegulatory toxicology and pharmacology116 dayssaveRefWorksSFX Info
Safety assessment of metarrestin in dogs: A clinical candidate targeting a subnuclear structure unique to metastatic cancer cellsRegulatory toxicology and pharmacology132 dayssaveRefWorksSFX Info
An analysis of skin lightening products' violations reported in four U.S. databases in 2002–2020: In hunt of surveillance quality enhancement, not just an assessment of the magnitude of the problemRegulatory toxicology and pharmacology133 dayssaveRefWorksSFX Info
Letter to the editors regarding Heringa et al. (2020)Regulatory toxicology and pharmacology133 dayssaveRefWorksSFX Info
Review of the pharmacokinetics and metabolism of triclopyr herbicide in mammals: Impact on safety assessmentsRegulatory toxicology and pharmacology133 dayssaveRefWorksSFX Info
Bolstering the existing database supporting the non-cancer Threshold of Toxicological Concern values with toxicity data on fragrance-related materialsRegulatory toxicology and pharmacology133 dayssaveRefWorksSFX Info
Use compatibility intervals in regulatory toxicologyRegulatory toxicology and pharmacology133 dayssaveRefWorksSFX Info
Rebuttal to the letter to the editors regarding Heringa et al. (2020)Regulatory toxicology and pharmacology137 dayssaveRefWorksSFX Info
Heavy metal contamination in recorded and unrecorded spirits. Should we worry?Regulatory toxicology and pharmacology137 dayssaveRefWorksSFX Info
A flow scheme for cumulative assessment of pesticides for adverse liver effectsRegulatory toxicology and pharmacology142 dayssaveRefWorksSFX Info
Template-based peptide modeling for celiac risk assessment of newly expressed proteins in GM cropsRegulatory toxicology and pharmacology142 dayssaveRefWorksSFX Info
Safety evaluation of E12, W8, X17, and Y9 potatoes: Nutritional evaluation and 90-day subchronic feeding study in ratsRegulatory toxicology and pharmacology144 dayssaveRefWorksSFX Info
Meta-analysis of animal studies applied to short-term inhalation exposure levels of hazardous chemicalsRegulatory toxicology and pharmacology149 dayssaveRefWorksSFX Info
Safety evaluation of Ochratoxin A and Citrinin after 28 days repeated dose oral exposure to Wistar ratsRegulatory toxicology and pharmacology154 dayssaveRefWorksSFX Info
Risk assessment of unintentional phthalates contaminants in cosmeticsRegulatory toxicology and pharmacology156 dayssaveRefWorksSFX Info
Response to “OECD 428 in vitro dermal absorption mass balance performance based on our in-house database of pesticide studies”Regulatory toxicology and pharmacology165 dayssaveRefWorksSFX Info
Effect of low- and high-level groundwater arsenic on peripheral blood and lung function of exposed rural womenRegulatory toxicology and pharmacology165 dayssaveRefWorksSFX Info
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