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Applying non-animal strategies for assessing skin sensitisation report from an EPAA/cefic-LRI/IFRA Europe cross sector workshop, ECHA helsinki, February 7th and 8th 2019Regulatory toxicology and pharmacology9 dayssaveRefWorksSFX Info
Evaluation of preclinical safety profile of SPH3127, a direct renin inhibitor, after 28-day repeated oral administration in Sprague-Dawley rats and cynomolgus monkeysRegulatory toxicology and pharmacology9 dayssaveRefWorksSFX Info
Subchronic toxicity evaluation of ethanol extract of Cassia tora L. seeds in ratsRegulatory toxicology and pharmacology12 dayssaveRefWorksSFX Info
Quantitative prediction of repeat dose toxicity values using GenRARegulatory toxicology and pharmacology20 dayssaveRefWorksSFX Info
Comparative levels of carbonyl delivery between mass-market cigars and cigarettesRegulatory toxicology and pharmacology20 dayssaveRefWorksSFX Info
Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA databaseRegulatory toxicology and pharmacology20 dayssaveRefWorksSFX Info
In vitro RHE skin sensitisation assays: Applicability to challenging substancesRegulatory toxicology and pharmacology20 dayssaveRefWorksSFX Info
Time to first cigarette of the day and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in adult regular and non-daily smokers: (NHANES) 2007–10Regulatory toxicology and pharmacology20 dayssaveRefWorksSFX Info
Derivation of a chronic reference dose for perfluorohexane sulfonate (PFHxS) for reproductive toxicity in miceRegulatory toxicology and pharmacology21 dayssaveRefWorksSFX Info
The ADME profile of the fungicide tricyclazole in rodent via the oral route: A critical review for human health safety assessmentRegulatory toxicology and pharmacology27 dayssaveRefWorksSFX Info
Consumer safety evaluation of pyraclostrobin residues in strawberry using liquid chromatography tandem mass spectrometry (LC-MS/MS): An Egyptian profileRegulatory toxicology and pharmacology34 dayssaveRefWorksSFX Info
Investigation of quality review issues and the association with application characteristics for new drug applications in first-cycle reviewsRegulatory toxicology and pharmacology37 dayssaveRefWorksSFX Info
Characterization of in vitro Mrp2 transporter model based on intestinal organoidsRegulatory toxicology and pharmacology40 dayssaveRefWorksSFX Info
Dissipation rates and residue levels of diflubenzuron and difenoconazole on peaches and dietary risk assessmentRegulatory toxicology and pharmacology43 dayssaveRefWorksSFX Info
Data derived Extrapolation Factors for developmental toxicity: A preliminary research case study with perfluorooctanoate (PFOA)Regulatory toxicology and pharmacology48 dayssaveRefWorksSFX Info
Reproductive and developmental toxicity screening of polyhexamethylene guanidine phosphate by oral gavage in ratsRegulatory toxicology and pharmacology49 dayssaveRefWorksSFX Info
Metabolomics as read-across tool: An example with 3-aminopropanol and 2-aminoethanolRegulatory toxicology and pharmacology49 dayssaveRefWorksSFX Info
Control performance of fish short term reproduction assays with fathead minnow (Pimephales promelas)Regulatory toxicology and pharmacology63 dayssaveRefWorksSFX Info
Elemental impurities in pharmaceutical products adding fuel to the fireRegulatory toxicology and pharmacology63 dayssaveRefWorksSFX Info
Nonclinical safety assessment of PF614: A novel TAAP prodrug of oxycodone for chronic pain indicationRegulatory toxicology and pharmacology63 dayssaveRefWorksSFX Info
Comparative pharmacokinetic and biodistribution study of two distinct squalene-containing oil-in-water emulsion adjuvants in H5N1 influenza vaccinesRegulatory toxicology and pharmacology63 dayssaveRefWorksSFX Info
Scientific assessments in European food law: Making it future-proofRegulatory toxicology and pharmacology72 dayssaveRefWorksSFX Info
Towards quantitative read across: Prediction of Ames mutagenicity in a large databaseRegulatory toxicology and pharmacology77 dayssaveRefWorksSFX Info
Determination of offspring NOAEL for zeta-cypermethrin using internal exposure data from rat developmental neurotoxicity studiesRegulatory toxicology and pharmacology81 dayssaveRefWorksSFX Info
Toxicology and human health risk assessment of polyethoxylated tallow amine surfactant used in glyphosate formulationsRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Investigation of number of replicate measurements required to meet cigarette smoke chemistry regulatory requirements measured under Canadian intense smoking conditionsRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Proposal of GHS sub-categorization criteria for LLNA: BrdU-ELISA (OECD TG442B)Regulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Exposure assessments in reproductive and developmental toxicity testing: An IQ-DruSafe industry survey on current practices and experiences in support of exposure-based high dose selectionRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Mechanistic relationship between biodegradation and bioaccumulation. Practical outcomesRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Testing developmental toxicity in a second species: are the differences due to species or replication error?Regulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Distribution of fluoride contamination in drinking water resources and health risk assessment using geographic information system, northwest IranRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Biosafety of unmodified ultrafine gold particles (AuPs) upon interacting with human blood components before systemic useRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Comparative study of feminine hygiene product regulations in Korea, the European Union, and the United StatesRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Evaluation of skin sensitization potential of chemicals by local lymph node assay using 5-bromo-2-deoxyuridine with flow cytometryRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Assessment of hypolipidemic, anti-inflammatory and antioxidant properties of medicinal plant Erica multiflora in triton WR-1339-induced hyperlipidemia and liver function repair in rats: A comparison with fenofibrateRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
In vitro and in vivo genotoxicity studies on monosodium L-glutamate monohydrateRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Garlic and allopurinol attenuate hepatic apoptosis induced by fipronil in male albino ratsRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Curation and analysis of clinical pathology parameters and histopathologic findings from eTOXsys, a large database project (eTOX) for toxicologic studiesRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Opinion of the Scientific Committee on consumer safety (SCCS) – Final opinion on the safety of fragrance ingredient Acetylated Vetiver Oil (AVO) - (Vetiveria zizanioides root extract acetylated) - Submission IIIRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Opinion of the Scientific Committee on Consumer safety (SCCS) – Opinion on Ethylzingerone - ‘Hydroxyethoxyphenyl Butanone’ (HEPB) - Cosmetics Europe No P98 - CAS No 569646-79-3 - Submission II (eye irritation)Regulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Genetic toxicology in silico protocolRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraineRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshopRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Bridging communities in the field of nanomedicineRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Non-relevance of acute dermal toxicity testing for assessing human health protection in the regulatory decision-making for agrochemical formulated productsRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
The impact on classifications for carcinogenicity, mutagenicity, reproductive and specific target organ toxicity after repeated exposure in the first ten years of the REACH regulationRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case studyRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Derivation of biomonitoring equivalents (BE values) for zincRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Innovative selection approach for a new antifungal agent mefentrifluconazole (Revysol®) and the impact upon its toxicity profileRegulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
Assessing in vitro dermal absorption of dry residues of agrochemical sprays using human skin within OECD TG 428Regulatory toxicology and pharmacology113 dayssaveRefWorksSFX Info
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