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In vivo safety testing of Antibody Drug ConjugatesRegulatory toxicology and pharmacology2 dayssaveRefWorksSFX Info
Harmonized 3Rs-based non-mutagenic impurity qualification study designs developed using the results of an IQ consortium surveyRegulatory toxicology and pharmacology3 dayssaveRefWorksSFX Info
Disease area and mode of action as criteria to asssign a default occupational exposure limitRegulatory toxicology and pharmacology5 dayssaveRefWorksSFX Info
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Preclinical safety evaluation of nafithromycin (WCK 4873) with emphasis on liver safety in rat and dogRegulatory toxicology and pharmacology7 dayssaveRefWorksSFX Info
Evaluation of the OECD QSAR toolbox automatic workflow for the prediction of the acute toxicity of organic chemicals to fathead minnowRegulatory toxicology and pharmacology9 dayssaveRefWorksSFX Info
In vitro skin penetration of bronidox, bronopol and formaldehyde from cosmeticsRegulatory toxicology and pharmacology10 dayssaveRefWorksSFX Info
Assessment of the toxicity and toxicokinetics of the novel potent tropomyosin receptor kinase (Trk) inhibitor LPM4870108 in rhesus monkeysRegulatory toxicology and pharmacology15 dayssaveRefWorksSFX Info
Human biomonitoring (HBM)-II values for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) - Description, derivation and discussionRegulatory toxicology and pharmacology23 dayssaveRefWorksSFX Info
Draize human repeat insult patch test (HRIPT): Seven decades of pitfalls and progressRegulatory toxicology and pharmacology26 dayssaveRefWorksSFX Info
Mercury in skin-care products in India and consumer exposure risksRegulatory toxicology and pharmacology26 dayssaveRefWorksSFX Info
Grouping of chemicals based on the potential mechanisms of hepatotoxicity of naphthalene and structurally similar chemicals using in vitro testing for read-across and its validationRegulatory toxicology and pharmacology26 dayssaveRefWorksSFX Info
Carcinogenicity and chronic toxicity of acrolein in rats and mice by two-year inhalation studyRegulatory toxicology and pharmacology26 dayssaveRefWorksSFX Info
Toxicity of boric acid, borax and other boron containing compounds: A reviewRegulatory toxicology and pharmacology30 dayssaveRefWorksSFX Info
Expanding the toxicologist's statistical toolbox: Using effect size estimation and dose-response modelling for holistic assessments instead of generic testingRegulatory toxicology and pharmacology32 dayssaveRefWorksSFX Info
Compounded conservatism in European re-entry worker risk assessment of pesticidesRegulatory toxicology and pharmacology32 dayssaveRefWorksSFX Info
Increasing confidence in waiving dermal toxicity studies: A comparison of oral and dermal acute data with alternative approaches for agrochemicals and productsRegulatory toxicology and pharmacology37 dayssaveRefWorksSFX Info
A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labellingRegulatory toxicology and pharmacology38 dayssaveRefWorksSFX Info
Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potentialRegulatory toxicology and pharmacology38 dayssaveRefWorksSFX Info
Risk assessment of predicted serum concentrations of bisphenol A in children and adults following treatment with dental composite restoratives, dental sealants, or orthodontic adhesives using physiologically based pharmacokinetic modelingRegulatory toxicology and pharmacology38 dayssaveRefWorksSFX Info
Estimation of toluene exposure in air from BMA (S-benzylmercapturic acid) urinary measures using a reverse dosimetry approach based on physiologically pharmacokinetic modelingRegulatory toxicology and pharmacology38 dayssaveRefWorksSFX Info
Comparative In vitro metabolism of purified mogrosides derived from monk fruit extractsRegulatory toxicology and pharmacology38 dayssaveRefWorksSFX Info
Evaluation of the carcinogenicity of dichloromethane in rats, mice, hamsters and humansRegulatory toxicology and pharmacology48 dayssaveRefWorksSFX Info
The use of emerging safety biomarkers in nonclinical and clinical safety assessment – The current and future state: An IQ DruSafe industry surveyRegulatory toxicology and pharmacology48 dayssaveRefWorksSFX Info
Testing the validity of a proposed dermal cancer slope factor for Benzo[a]pyreneRegulatory toxicology and pharmacology53 dayssaveRefWorksSFX Info
Incorporating lines of evidence from New Approach Methodologies (NAMs) to reduce uncertainties in a category based read-across: A case study for repeated dose toxicityRegulatory toxicology and pharmacology58 dayssaveRefWorksSFX Info
A 13-week subchronic toxicity study of a Dioscorea Rhizome water extract in ratsRegulatory toxicology and pharmacology58 dayssaveRefWorksSFX Info
Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samplesRegulatory toxicology and pharmacology64 dayssaveRefWorksSFX Info
Reproductive and developmental toxicity screening study of an acetone extract of rosemaryRegulatory toxicology and pharmacology66 dayssaveRefWorksSFX Info
Evidence-based regulations for bioinformatic prediction of allergen cross-reactivity are neededRegulatory toxicology and pharmacology71 dayssaveRefWorksSFX Info
Antimony release from polyester textiles by artificial sweat solutions: A call for a standardized procedureRegulatory toxicology and pharmacology71 dayssaveRefWorksSFX Info
Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig modelRegulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
A review to support the derivation of a worst-case dermal penetration value for nanoparticlesRegulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
Subchronic toxicity study in rats evaluating herbicide-tolerant soybean DAS-68416-4Regulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
Simple methodology for ensuring the precision of measuring radioactivity at low concentrations in very small tissues using quantitative whole-body autoradiographyRegulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
Evaluating chemical similarity as a measure to identify potential substances of very high concernRegulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studiesRegulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
Assessment of the potential allergenicity and toxicity of Pichia proteins in a novel leghemoglobin preparationRegulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
A call for action on the development and implementation of new methodologies for safety assessment of chemical-based products in the EU – A short communicationRegulatory toxicology and pharmacology85 dayssaveRefWorksSFX Info
Safety assessment of ethanolic root extract of Zaleya decandra (EEZD) in Wistar ratsRegulatory toxicology and pharmacology89 dayssaveRefWorksSFX Info
The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analysesRegulatory toxicology and pharmacology106 dayssaveRefWorksSFX Info
Considerations when deriving compound-specific limits for extractables and leachables from pharmaceutical products: Four case studiesRegulatory toxicology and pharmacology109 dayssaveRefWorksSFX Info
Facilitation of risk assessment with evidence-based methods – A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertaintyRegulatory toxicology and pharmacology115 dayssaveRefWorksSFX Info
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophenRegulatory toxicology and pharmacology115 dayssaveRefWorksSFX Info
Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materialsRegulatory toxicology and pharmacology121 dayssaveRefWorksSFX Info
A review of clinical pharmacology deficiencies of European centralised drug marketing authorisation applicationsRegulatory toxicology and pharmacology128 dayssaveRefWorksSFX Info
Assessment of veterinary drug residues in food: Considerations when dealing with sub-optimal dataRegulatory toxicology and pharmacology136 dayssaveRefWorksSFX Info
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicalsRegulatory toxicology and pharmacology140 dayssaveRefWorksSFX Info
Toxicological risk assessment of bisphenol a released from dialyzers under simulated-use and exaggerated extraction conditionsRegulatory toxicology and pharmacology140 dayssaveRefWorksSFX Info
Safety of medicinal comfrey cream preparations (Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skinRegulatory toxicology and pharmacology144 dayssaveRefWorksSFX Info
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