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Toxicity of boric acid, borax and other boron containing compounds: A reviewRegulatory toxicology and pharmacology270 dayssaveRefWorksSFX Info
Expanding the toxicologist's statistical toolbox: Using effect size estimation and dose-response modelling for holistic assessments instead of generic testingRegulatory toxicology and pharmacology272 dayssaveRefWorksSFX Info
Compounded conservatism in European re-entry worker risk assessment of pesticidesRegulatory toxicology and pharmacology272 dayssaveRefWorksSFX Info
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A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labellingRegulatory toxicology and pharmacology278 dayssaveRefWorksSFX Info
Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potentialRegulatory toxicology and pharmacology278 dayssaveRefWorksSFX Info
Risk assessment of predicted serum concentrations of bisphenol A in children and adults following treatment with dental composite restoratives, dental sealants, or orthodontic adhesives using physiologically based pharmacokinetic modelingRegulatory toxicology and pharmacology278 dayssaveRefWorksSFX Info
Estimation of toluene exposure in air from BMA (S-benzylmercapturic acid) urinary measures using a reverse dosimetry approach based on physiologically pharmacokinetic modelingRegulatory toxicology and pharmacology278 dayssaveRefWorksSFX Info
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Evaluation of the carcinogenicity of dichloromethane in rats, mice, hamsters and humansRegulatory toxicology and pharmacology288 dayssaveRefWorksSFX Info
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Testing the validity of a proposed dermal cancer slope factor for Benzo[a]pyreneRegulatory toxicology and pharmacology293 dayssaveRefWorksSFX Info
Incorporating lines of evidence from New Approach Methodologies (NAMs) to reduce uncertainties in a category based read-across: A case study for repeated dose toxicityRegulatory toxicology and pharmacology299 dayssaveRefWorksSFX Info
A 13-week subchronic toxicity study of a Dioscorea Rhizome water extract in ratsRegulatory toxicology and pharmacology299 dayssaveRefWorksSFX Info
Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samplesRegulatory toxicology and pharmacology304 dayssaveRefWorksSFX Info
Reproductive and developmental toxicity screening study of an acetone extract of rosemaryRegulatory toxicology and pharmacology306 dayssaveRefWorksSFX Info
Evidence-based regulations for bioinformatic prediction of allergen cross-reactivity are neededRegulatory toxicology and pharmacology312 dayssaveRefWorksSFX Info
Antimony release from polyester textiles by artificial sweat solutions: A call for a standardized procedureRegulatory toxicology and pharmacology312 dayssaveRefWorksSFX Info
Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig modelRegulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
A review to support the derivation of a worst-case dermal penetration value for nanoparticlesRegulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
Subchronic toxicity study in rats evaluating herbicide-tolerant soybean DAS-68416-4Regulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
Simple methodology for ensuring the precision of measuring radioactivity at low concentrations in very small tissues using quantitative whole-body autoradiographyRegulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
Evaluating chemical similarity as a measure to identify potential substances of very high concernRegulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studiesRegulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
Assessment of the potential allergenicity and toxicity of Pichia proteins in a novel leghemoglobin preparationRegulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
A call for action on the development and implementation of new methodologies for safety assessment of chemical-based products in the EU – A short communicationRegulatory toxicology and pharmacology325 dayssaveRefWorksSFX Info
Safety assessment of ethanolic root extract of Zaleya decandra (EEZD) in Wistar ratsRegulatory toxicology and pharmacology329 dayssaveRefWorksSFX Info
The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analysesRegulatory toxicology and pharmacology346 dayssaveRefWorksSFX Info
Considerations when deriving compound-specific limits for extractables and leachables from pharmaceutical products: Four case studiesRegulatory toxicology and pharmacology349 dayssaveRefWorksSFX Info
Facilitation of risk assessment with evidence-based methods – A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertaintyRegulatory toxicology and pharmacology355 dayssaveRefWorksSFX Info
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophenRegulatory toxicology and pharmacology355 dayssaveRefWorksSFX Info
Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materialsRegulatory toxicology and pharmacology361 dayssaveRefWorksSFX Info
A review of clinical pharmacology deficiencies of European centralised drug marketing authorisation applicationsRegulatory toxicology and pharmacology368 dayssaveRefWorksSFX Info
Assessment of veterinary drug residues in food: Considerations when dealing with sub-optimal dataRegulatory toxicology and pharmacology376 dayssaveRefWorksSFX Info
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicalsRegulatory toxicology and pharmacology380 dayssaveRefWorksSFX Info
Toxicological risk assessment of bisphenol a released from dialyzers under simulated-use and exaggerated extraction conditionsRegulatory toxicology and pharmacology380 dayssaveRefWorksSFX Info
Safety of medicinal comfrey cream preparations (Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skinRegulatory toxicology and pharmacology384 dayssaveRefWorksSFX Info
Acute and sub-chronic toxicity studies of Benincasa hispida (Thunb.) cogniaux fruit extract in rodentsRegulatory toxicology and pharmacology394 dayssaveRefWorksSFX Info
Read-across can increase confidence in the Next Generation Risk Assessment for skin sensitisation: A case study with resorcinolRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Iraqi regulatory authority current system and experience with biosimilarsRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Building confidence in skin sensitisation potency assessment using new approach methodologies: report of the 3rd EPAA Partners Forum, Brussels, 28th October 2019Regulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
A toxicological evaluation of monomethylsilanetriol (MMST) stabilized in acacia gum, a novel silicon preparationRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Use of mechanistic information to derive chemical-specific adjustment factors – Refinement of risk assessmentRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
DP-2Ø2216-6 maize does not adversely affect rats in a 90-day feeding studyRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Safety testing of adult novelties using in vitro methodsRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
A 26-week toxicological study of Xuezhikang (XZK), red yeast rice extract, in Beagle dogs with a 4-week recovery periodRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Four-week repeated dose oral toxicity study of KDS2010, a novel selective monoamine oxidase B inhibitor, in Sprague Dawley ratsRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Effects of an ethanolic extract and fractions from Piper glabratum (Piperaceae) leaves on pain and inflammationRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Development of peptide therapeutics: A nonclinical safety assessment perspectiveRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
Reflections on the OECD guidelines for in vitro skin absorption studiesRegulatory toxicology and pharmacology407 dayssaveRefWorksSFX Info
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