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Terkko 2005-2021
In vivo safety testing of Antibody Drug Conjugates
Regulatory toxicology and pharmacology
2 days
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Harmonized 3Rs-based non-mutagenic impurity qualification study designs developed using the results of an IQ consortium survey
Regulatory toxicology and pharmacology
3 days
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Disease area and mode of action as criteria to asssign a default occupational exposure limit
Regulatory toxicology and pharmacology
5 days
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Probabilistic pharmacokinetic modeling of airborne lead corresponding to toxicologically relevant blood lead levels in workers
Regulatory toxicology and pharmacology
7 days
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Preclinical safety evaluation of nafithromycin (WCK 4873) with emphasis on liver safety in rat and dog
Regulatory toxicology and pharmacology
7 days
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Evaluation of the OECD QSAR toolbox automatic workflow for the prediction of the acute toxicity of organic chemicals to fathead minnow
Regulatory toxicology and pharmacology
9 days
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In vitro skin penetration of bronidox, bronopol and formaldehyde from cosmetics
Regulatory toxicology and pharmacology
10 days
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Assessment of the toxicity and toxicokinetics of the novel potent tropomyosin receptor kinase (Trk) inhibitor LPM4870108 in rhesus monkeys
Regulatory toxicology and pharmacology
15 days
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Human biomonitoring (HBM)-II values for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) - Description, derivation and discussion
Regulatory toxicology and pharmacology
23 days
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Draize human repeat insult patch test (HRIPT): Seven decades of pitfalls and progress
Regulatory toxicology and pharmacology
26 days
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Mercury in skin-care products in India and consumer exposure risks
Regulatory toxicology and pharmacology
26 days
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Grouping of chemicals based on the potential mechanisms of hepatotoxicity of naphthalene and structurally similar chemicals using in vitro testing for read-across and its validation
Regulatory toxicology and pharmacology
26 days
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Carcinogenicity and chronic toxicity of acrolein in rats and mice by two-year inhalation study
Regulatory toxicology and pharmacology
26 days
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Toxicity of boric acid, borax and other boron containing compounds: A review
Regulatory toxicology and pharmacology
30 days
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Expanding the toxicologist's statistical toolbox: Using effect size estimation and dose-response modelling for holistic assessments instead of generic testing
Regulatory toxicology and pharmacology
32 days
save
Compounded conservatism in European re-entry worker risk assessment of pesticides
Regulatory toxicology and pharmacology
32 days
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Increasing confidence in waiving dermal toxicity studies: A comparison of oral and dermal acute data with alternative approaches for agrochemicals and products
Regulatory toxicology and pharmacology
37 days
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A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling
Regulatory toxicology and pharmacology
38 days
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Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential
Regulatory toxicology and pharmacology
38 days
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Risk assessment of predicted serum concentrations of bisphenol A in children and adults following treatment with dental composite restoratives, dental sealants, or orthodontic adhesives using physiologically based pharmacokinetic modeling
Regulatory toxicology and pharmacology
38 days
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Estimation of toluene exposure in air from BMA (S-benzylmercapturic acid) urinary measures using a reverse dosimetry approach based on physiologically pharmacokinetic modeling
Regulatory toxicology and pharmacology
38 days
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Comparative In vitro metabolism of purified mogrosides derived from monk fruit extracts
Regulatory toxicology and pharmacology
38 days
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Evaluation of the carcinogenicity of dichloromethane in rats, mice, hamsters and humans
Regulatory toxicology and pharmacology
48 days
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The use of emerging safety biomarkers in nonclinical and clinical safety assessment – The current and future state: An IQ DruSafe industry survey
Regulatory toxicology and pharmacology
48 days
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Testing the validity of a proposed dermal cancer slope factor for Benzo[a]pyrene
Regulatory toxicology and pharmacology
53 days
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Incorporating lines of evidence from New Approach Methodologies (NAMs) to reduce uncertainties in a category based read-across: A case study for repeated dose toxicity
Regulatory toxicology and pharmacology
58 days
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A 13-week subchronic toxicity study of a Dioscorea Rhizome water extract in rats
Regulatory toxicology and pharmacology
58 days
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Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples
Regulatory toxicology and pharmacology
64 days
save
Reproductive and developmental toxicity screening study of an acetone extract of rosemary
Regulatory toxicology and pharmacology
66 days
save
Evidence-based regulations for bioinformatic prediction of allergen cross-reactivity are needed
Regulatory toxicology and pharmacology
71 days
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Antimony release from polyester textiles by artificial sweat solutions: A call for a standardized procedure
Regulatory toxicology and pharmacology
71 days
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Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model
Regulatory toxicology and pharmacology
85 days
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A review to support the derivation of a worst-case dermal penetration value for nanoparticles
Regulatory toxicology and pharmacology
85 days
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Subchronic toxicity study in rats evaluating herbicide-tolerant soybean DAS-68416-4
Regulatory toxicology and pharmacology
85 days
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Simple methodology for ensuring the precision of measuring radioactivity at low concentrations in very small tissues using quantitative whole-body autoradiography
Regulatory toxicology and pharmacology
85 days
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Evaluating chemical similarity as a measure to identify potential substances of very high concern
Regulatory toxicology and pharmacology
85 days
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Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies
Regulatory toxicology and pharmacology
85 days
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Assessment of the potential allergenicity and toxicity of Pichia proteins in a novel leghemoglobin preparation
Regulatory toxicology and pharmacology
85 days
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A call for action on the development and implementation of new methodologies for safety assessment of chemical-based products in the EU – A short communication
Regulatory toxicology and pharmacology
85 days
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Safety assessment of ethanolic root extract of Zaleya decandra (EEZD) in Wistar rats
Regulatory toxicology and pharmacology
89 days
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The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analyses
Regulatory toxicology and pharmacology
106 days
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Considerations when deriving compound-specific limits for extractables and leachables from pharmaceutical products: Four case studies
Regulatory toxicology and pharmacology
109 days
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Facilitation of risk assessment with evidence-based methods – A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertainty
Regulatory toxicology and pharmacology
115 days
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Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen
Regulatory toxicology and pharmacology
115 days
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Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materials
Regulatory toxicology and pharmacology
121 days
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A review of clinical pharmacology deficiencies of European centralised drug marketing authorisation applications
Regulatory toxicology and pharmacology
128 days
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Assessment of veterinary drug residues in food: Considerations when dealing with sub-optimal data
Regulatory toxicology and pharmacology
136 days
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A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals
Regulatory toxicology and pharmacology
140 days
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Toxicological risk assessment of bisphenol a released from dialyzers under simulated-use and exaggerated extraction conditions
Regulatory toxicology and pharmacology
140 days
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Safety of medicinal comfrey cream preparations (Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skin
Regulatory toxicology and pharmacology
144 days
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