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Read-across can increase confidence in the Next Generation Risk Assessment for skin sensitisation: A case study with resorcinolRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Iraqi regulatory authority current system and experience with biosimilarsRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Building confidence in skin sensitisation potency assessment using new approach methodologies: report of the 3rd EPAA Partners Forum, Brussels, 28th October 2019Regulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
A toxicological evaluation of monomethylsilanetriol (MMST) stabilized in acacia gum, a novel silicon preparationRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Use of mechanistic information to derive chemical-specific adjustment factors – Refinement of risk assessmentRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
DP-2Ø2216-6 maize does not adversely affect rats in a 90-day feeding studyRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Safety testing of adult novelties using in vitro methodsRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
A 26-week toxicological study of Xuezhikang (XZK), red yeast rice extract, in Beagle dogs with a 4-week recovery periodRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Four-week repeated dose oral toxicity study of KDS2010, a novel selective monoamine oxidase B inhibitor, in Sprague Dawley ratsRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Effects of an ethanolic extract and fractions from Piper glabratum (Piperaceae) leaves on pain and inflammationRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Development of peptide therapeutics: A nonclinical safety assessment perspectiveRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Reflections on the OECD guidelines for in vitro skin absorption studiesRegulatory toxicology and pharmacology6 dayssaveRefWorksSFX Info
Nonclinical safety assessment of epigenetic modulatory drugs: Current status and industry perspectiveRegulatory toxicology and pharmacology11 dayssaveRefWorksSFX Info
Can we define a level of protection for allergic consumers that everyone can accept?Regulatory toxicology and pharmacology16 dayssaveRefWorksSFX Info
Copper alloys’ metal migration and bioaccessibility in saliva and gastric fluidRegulatory toxicology and pharmacology16 dayssaveRefWorksSFX Info
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendationsRegulatory toxicology and pharmacology26 dayssaveRefWorksSFX Info
Evaluation of chronic toxicity of cyclocreatine, a creatine analog, in Sprague Dawley rat after oral gavage administration for up to 26 weeksRegulatory toxicology and pharmacology28 dayssaveRefWorksSFX Info
Selecting a minimal set of androgen receptor assays for screening chemicalsRegulatory toxicology and pharmacology28 dayssaveRefWorksSFX Info
Dose-response assessment for impaired memory from chronic exposure to domoic acid among native American consumers of razor clamsRegulatory toxicology and pharmacology34 dayssaveRefWorksSFX Info
“New statistics” in regulatory toxicology?Regulatory toxicology and pharmacology34 dayssaveRefWorksSFX Info
Me-too validation study for in vitro skin irritation test with a reconstructed human epidermis model, KeraSkin™ for OECD test guideline 439Regulatory toxicology and pharmacology35 dayssaveRefWorksSFX Info
Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in miceRegulatory toxicology and pharmacology50 dayssaveRefWorksSFX Info
Use of the kinetically-derived maximum dose: Opportunities for delivering 3Rs benefitsRegulatory toxicology and pharmacology50 dayssaveRefWorksSFX Info
Safety assessment of metarrestin in dogs: A clinical candidate targeting a subnuclear structure unique to metastatic cancer cellsRegulatory toxicology and pharmacology66 dayssaveRefWorksSFX Info
An analysis of skin lightening products' violations reported in four U.S. databases in 2002–2020: In hunt of surveillance quality enhancement, not just an assessment of the magnitude of the problemRegulatory toxicology and pharmacology67 dayssaveRefWorksSFX Info
Letter to the editors regarding Heringa et al. (2020)Regulatory toxicology and pharmacology67 dayssaveRefWorksSFX Info
Review of the pharmacokinetics and metabolism of triclopyr herbicide in mammals: Impact on safety assessmentsRegulatory toxicology and pharmacology67 dayssaveRefWorksSFX Info
Bolstering the existing database supporting the non-cancer Threshold of Toxicological Concern values with toxicity data on fragrance-related materialsRegulatory toxicology and pharmacology67 dayssaveRefWorksSFX Info
Use compatibility intervals in regulatory toxicologyRegulatory toxicology and pharmacology67 dayssaveRefWorksSFX Info
Rebuttal to the letter to the editors regarding Heringa et al. (2020)Regulatory toxicology and pharmacology71 dayssaveRefWorksSFX Info
Heavy metal contamination in recorded and unrecorded spirits. Should we worry?Regulatory toxicology and pharmacology71 dayssaveRefWorksSFX Info
A flow scheme for cumulative assessment of pesticides for adverse liver effectsRegulatory toxicology and pharmacology76 dayssaveRefWorksSFX Info
Template-based peptide modeling for celiac risk assessment of newly expressed proteins in GM cropsRegulatory toxicology and pharmacology76 dayssaveRefWorksSFX Info
Safety evaluation of E12, W8, X17, and Y9 potatoes: Nutritional evaluation and 90-day subchronic feeding study in ratsRegulatory toxicology and pharmacology78 dayssaveRefWorksSFX Info
Meta-analysis of animal studies applied to short-term inhalation exposure levels of hazardous chemicalsRegulatory toxicology and pharmacology83 dayssaveRefWorksSFX Info
Safety evaluation of Ochratoxin A and Citrinin after 28 days repeated dose oral exposure to Wistar ratsRegulatory toxicology and pharmacology88 dayssaveRefWorksSFX Info
Risk assessment of unintentional phthalates contaminants in cosmeticsRegulatory toxicology and pharmacology90 dayssaveRefWorksSFX Info
Response to “OECD 428 in vitro dermal absorption mass balance performance based on our in-house database of pesticide studies”Regulatory toxicology and pharmacology99 dayssaveRefWorksSFX Info
Effect of low- and high-level groundwater arsenic on peripheral blood and lung function of exposed rural womenRegulatory toxicology and pharmacology99 dayssaveRefWorksSFX Info
Hydroalcoholic extract of leaf of Arachis hypogaea L. (Fabaceae) did not induce toxic effects in the repeated-dose toxicity study in ratsRegulatory toxicology and pharmacology99 dayssaveRefWorksSFX Info
Toxicological testing of a photoactive phthalocyanine-based antimicrobial substanceRegulatory toxicology and pharmacology110 dayssaveRefWorksSFX Info
New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky WorkshopRegulatory toxicology and pharmacology141 dayssaveRefWorksSFX Info
Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across: An EFSA funded projectRegulatory toxicology and pharmacology141 dayssaveRefWorksSFX Info
Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicityRegulatory toxicology and pharmacology142 dayssaveRefWorksSFX Info
Safety evaluation of water extract of Gastrodia elata Blume: Genotoxicity and 28-day oral toxicity studiesRegulatory toxicology and pharmacology143 dayssaveRefWorksSFX Info
Toxicological evaluation of, red rice yeast extract, Xuezhikang: Acute, 26-week chronic and genotoxicity studiesRegulatory toxicology and pharmacology149 dayssaveRefWorksSFX Info
A semi-automated workflow for adverse outcome pathway hypothesis generation: The use case of non-genotoxic induced hepatocellular carcinomaRegulatory toxicology and pharmacology163 dayssaveRefWorksSFX Info
Rat two-generation reproductive toxicity and teratogenicity studies of a novel coccidiostat – EthanamizurilRegulatory toxicology and pharmacology182 dayssaveRefWorksSFX Info
“Natural” is not synonymous with “Safe”: Toxicity of natural products alone and in combination with pharmaceutical agentsRegulatory toxicology and pharmacology182 dayssaveRefWorksSFX Info
Chimeric hemagglutinin supra-seasonal universal influenza vaccine candidates administered sequentially by the intramuscular route are locally and systemically well-tolerated in rabbitsRegulatory toxicology and pharmacology182 dayssaveRefWorksSFX Info
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