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Transcriptome analysis revealed the mechanism of the metabolic toxicity and susceptibility of di-(2-ethylhexyl)phthalate on adolescent male ICR mice with type 2 diabetes mellitus.Archives of Toxicology16 hourssaveRefWorksSFX Info
The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in mice.Archives of Toxicology16 hourssaveRefWorksSFX Info
Identification of glycyrrhizin metabolites in humans and of a potential biomarker of liquorice-induced pseudoaldosteronism: a multi-centre cross-sectional study.Archives of Toxicology1 daysaveRefWorksSFX Info
The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro.Archives of Toxicology2 dayssaveRefWorksSFX Info
Novel insights into the mechanism of cyclophosphamide-induced bladder toxicity: chloroacetaldehyde's contribution to urothelial dysfunction in vitro.Archives of Toxicology3 dayssaveRefWorksSFX Info
Hair analysis for the biomonitoring of polycyclic aromatic hydrocarbon exposure: comparison with urinary metabolites and DNA adducts in a rat model.Archives of Toxicology3 dayssaveRefWorksSFX Info
Mechanistic evidence that benzo[a]pyrene promotes an inflammatory microenvironment that drives the metastatic potential of human mammary cells.Archives of Toxicology3 dayssaveRefWorksSFX Info
A novel multi-parametric high content screening assay in ciPTEC-OAT1 to predict drug-induced nephrotoxicity during drug discovery.Archives of Toxicology3 dayssaveRefWorksSFX Info
In vitro assessment of hepatotoxicity by metabolomics: a review.Archives of Toxicology3 dayssaveRefWorksSFX Info
In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats.Archives of Toxicology3 dayssaveRefWorksSFX Info
3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo.Archives of Toxicology3 dayssaveRefWorksSFX Info
Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes.Archives of Toxicology3 dayssaveRefWorksSFX Info
Evaluation of FSH, LH, testosterone levels and semen parameters in male boron workers under extreme exposure conditions.Archives of Toxicology3 dayssaveRefWorksSFX Info
Possible neurotoxicity of the anesthetic propofol: evidence for the inhibition of complex II of the respiratory chain in area CA3 of rat hippocampal slices.Archives of Toxicology3 dayssaveRefWorksSFX Info
Characterization of hepatocyte-based in vitro systems for reliable toxicity testing.Archives of Toxicology3 dayssaveRefWorksSFX Info
Advancing the predictivity of skin sensitization by applying a novel HMOX1 reporter system.Archives of Toxicology3 dayssaveRefWorksSFX Info
2,4-Dimethylaniline generates phosphorylated histone H2AX in human urothelial and hepatic cells through reactive oxygen species produced by cytochrome P450 2E1.Archives of Toxicology3 dayssaveRefWorksSFX Info
PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms.Archives of Toxicology3 dayssaveRefWorksSFX Info
Drugs of abuse from a different toxicological perspective: an updated review of cocaine genotoxicity.Archives of Toxicology3 dayssaveRefWorksSFX Info
Effect of acute exposure to toluene on cortical excitability, neuroplasticity, and motor learning in healthy humans.Archives of Toxicology3 dayssaveRefWorksSFX Info
Chemical-induced contact allergy: from mechanistic understanding to risk prevention.Archives of Toxicology3 dayssaveRefWorksSFX Info
Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells.Archives of Toxicology3 dayssaveRefWorksSFX Info
Birth weights of newborns and pregnancy outcomes of environmentally boron-exposed females in Turkey.Archives of Toxicology6 dayssaveRefWorksSFX Info
Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models.Archives of Toxicology6 dayssaveRefWorksSFX Info
Opioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects.Archives of Toxicology6 dayssaveRefWorksSFX Info
Autophagy and acetaminophen-induced hepatotoxicity.Archives of Toxicology6 dayssaveRefWorksSFX Info
Aged rats are more vulnerable than adolescents to "ecstasy"-induced toxicity.Archives of Toxicology6 dayssaveRefWorksSFX Info
Comparison of iohexol and iodixanol induced nephrotoxicity, mitochondrial damage and mitophagy in a new contrast-induced acute kidney injury rat model.Archives of Toxicology6 dayssaveRefWorksSFX Info
Humoral and cellular immune response in Wistar Han RCC rats fed two genetically modified maize MON810 varieties for 90 days (EU 7th Framework Programme project GRACE).Archives of Toxicology6 dayssaveRefWorksSFX Info
Ethanol addictively enhances the in vitro cardiotoxicity of cocaine through oxidative damage, energetic deregulation, and apoptosis.Archives of Toxicology6 dayssaveRefWorksSFX Info
The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells.Archives of Toxicology6 dayssaveRefWorksSFX Info
Galunisertib modifies the liver fibrotic composition in the Abcb4Ko mouse model.Archives of Toxicology6 dayssaveRefWorksSFX Info
Chronic ingestion of deoxynivalenol at human dietary levels impairs intestinal homeostasis and gut microbiota in mice.Archives of Toxicology6 dayssaveRefWorksSFX Info
Revisiting the stress paradigm for silica nanoparticles: decoupling of the anti-oxidative defense, pro-inflammatory response and cytotoxicity.Archives of Toxicology6 dayssaveRefWorksSFX Info
The impact of desorption kinetics from albumin on hepatic extraction efficiency and hepatic clearance: a model study.Archives of Toxicology6 dayssaveRefWorksSFX Info
Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity.Archives of Toxicology6 dayssaveRefWorksSFX Info
FRZB1 rs2242070 polymorphisms is associated with brick tea type skeletal fluorosis in Kazakhs, but not in Tibetans, China.Archives of Toxicology6 dayssaveRefWorksSFX Info
Computational identification of structural factors affecting the mutagenic potential of aromatic amines: study design and experimental validation.Archives of Toxicology6 dayssaveRefWorksSFX Info
Prediction of deoxynivalenol toxicokinetics in humans by in vitro-to-in vivo extrapolation and allometric scaling of in vivo animal data.Archives of Toxicology6 dayssaveRefWorksSFX Info
Validity of different biomonitoring parameters for the assessment of occupational exposure to N,N-dimethylformamide (DMF).Archives of Toxicology6 dayssaveRefWorksSFX Info
Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation.Archives of Toxicology6 dayssaveRefWorksSFX Info
Polymyxin B causes DNA damage in HK-2 cells and mice.Archives of Toxicology6 dayssaveRefWorksSFX Info
The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro.Archives of Toxicology8 dayssaveRefWorksSFX Info
Heat shock protein 70 is a key molecule to rescue imbalance caused by low-frequency noise.Archives of Toxicology11 dayssaveRefWorksSFX Info
Upregulation of let-7f-2-3p by long noncoding RNA NEAT1 inhibits XPO1-mediated HAX-1 nuclear export in both in vitro and in vivo rodent models of doxorubicin-induced cardiotoxicity.Archives of Toxicology12 dayssaveRefWorksSFX Info
T-2 toxin neurotoxicity: role of oxidative stress and mitochondrial dysfunction.Archives of Toxicology12 dayssaveRefWorksSFX Info
Artemisinin suppresses hepatocellular carcinoma cell growth, migration and invasion by targeting cellular bioenergetics and Hippo-YAP signaling.Archives of Toxicology14 dayssaveRefWorksSFX Info
Naturally occurring mixtures of Alternaria toxins: anti-estrogenic and genotoxic effects in vitro.Archives of Toxicology16 dayssaveRefWorksSFX Info
Gene expression and cytosine DNA methylation alterations in induced pluripotent stem-cell-derived human hepatocytes treated with low doses of chemical carcinogens.Archives of Toxicology17 dayssaveRefWorksSFX Info
Arsenic is more potent than cadmium or manganese in disrupting the INS-1 beta cell microRNA landscape.Archives of Toxicology17 dayssaveRefWorksSFX Info
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