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[ASAP] Recent Advances in the Solid- and Solution-Phase Synthesis of Peptides and Proteins Using Microflow TechnologyOrganic Process Research and Development1 daysaveRefWorksSFX Info
[ASAP] Multigram Scale Synthesis of Piperarborenines C‑EOrganic Process Research and Development1 daysaveRefWorksSFX Info
[ASAP] Correction to“Thermal Instability and Associated Potential Safety Hazards of Rhodium(I) Precatalyst Complexes with Weakly Coordinated Ligands”Organic Process Research and Development3 dayssaveRefWorksSFX Info
[ASAP] Cu-Mediated Ullmann-Type Cross-Coupling and Industrial Applications in Route Design, Process Development, and Scale-up of Pharmaceutical and Agrochemical ProcessesOrganic Process Research and Development4 dayssaveRefWorksSFX Info
[ASAP] Enantioselective Synthesis of the Chiral Pyrrolidine Fragment of Upadacitinib <italic toggle="yes">via</italic> Chiral Auxiliary Directed Diastereoselective 1,3-Dipolar CycloadditionOrganic Process Research and Development7 dayssaveRefWorksSFX Info
[ASAP] Discovery and Process Development of a Scalable Biocatalytic Kinetic Resolution toward Synthesis of a Sterically Hindered Chiral KetoneOrganic Process Research and Development10 dayssaveRefWorksSFX Info
[ASAP] Synthesis of 5‑Nitrotetrazolate via the Aqueous Oxidation of 5‑AminotetrazoleOrganic Process Research and Development17 dayssaveRefWorksSFX Info
[ASAP] Highly Enantioselective Hydroxylation of 3‑Arylpropanenitriles to Access Chiral β‑Hydroxy Nitriles by Engineering of P450pyr MonooxygenaseOrganic Process Research and Development17 dayssaveRefWorksSFX Info
[ASAP] Some Items of Interest to Process R&D Chemists and EngineersOrganic Process Research and Development17 dayssaveRefWorksSFX Info
[ASAP] Fit-for-Purpose Synthesis of an Aza-Cryptophycin Analogue as the Payload for an Antibody–Drug ConjugateOrganic Process Research and Development17 dayssaveRefWorksSFX Info
[ASAP] Manufacturable Process of a Novel EGFR Inhibitor (Larotinib) for the Treatment of ESCCOrganic Process Research and Development18 dayssaveRefWorksSFX Info
[ASAP] Missing Link: Enabling Loading of 2‑Chlorotrityl Chloride Resin in <italic toggle="yes">N</italic>‑Butylpyrrolidinone as a Green SolventOrganic Process Research and Development22 dayssaveRefWorksSFX Info
[ASAP] Optimization of Metal Affinity Ketoreductase Immobilization for Application in Batch and Flow ProcessesOrganic Process Research and Development23 dayssaveRefWorksSFX Info
[ASAP] Melting Effect on the Thermal Hazard of Anthraquinone Dyes Waste: Based on the Thermal Decomposition Characteristics and Quantum MechanicsOrganic Process Research and Development25 dayssaveRefWorksSFX Info
[ASAP] Synthesis of 5‑Substituted Tetrazoles: Reaction of Azide Salts with Organonitriles Catalyzed by Trialkylammonium Salts in Non-polar MediaOrganic Process Research and Development29 dayssaveRefWorksSFX Info
[ASAP] Online and In Situ Monitoring of the Exchange, Transmetalation, and Cross-Coupling of a Negishi ReactionOrganic Process Research and Development29 dayssaveRefWorksSFX Info
[ASAP] Selective Photochemical Continuous Flow Benzylic MonochlorinationOrganic Process Research and Development30 dayssaveRefWorksSFX Info
[ASAP] Correction to“Effective Phosphorylation of 2,2′-Methylene-bis(4,6-di-<italic toggle="yes">tert</italic>-butyl) Phenol in Continuous Flow Reactors”Organic Process Research and Development30 dayssaveRefWorksSFX Info
[ASAP] Highly Efficient and Selective Hydrogenation of Sugars Catalyzed by Ru-MACHO-BH: Practical Synthesis of Sugar AlcoholsOrganic Process Research and Development32 dayssaveRefWorksSFX Info
[ASAP] Electrochemical Oxidation of Alcohols Using Nickel Oxide Hydroxide as Heterogeneous Electrocatalyst in Batch and Continuous FlowOrganic Process Research and Development34 dayssaveRefWorksSFX Info
[ASAP] Thermal and Kinetic Research on a Highly Exothermic Condensation Reaction by Powerful CalorimetersOrganic Process Research and Development36 dayssaveRefWorksSFX Info
[ASAP] Development of a Process to a 4‑Arylated 2‑Methylisoquinolin-1(2<italic toggle="yes">H</italic>)‑one for the Treatment of Solid Tumors: Lessons in Ortho-Bromination, Selective Solubility, Pd Deactivation, and Form ControlOrganic Process Research and Development37 dayssaveRefWorksSFX Info
[ASAP] Continuous Processing of Concentrated Organolithiums in Flow Using Static and Dynamic Spinning Disc Reactor TechnologiesOrganic Process Research and Development38 dayssaveRefWorksSFX Info
[ASAP] Evaluation of the Thermal Hazard of the Oxidation Reaction in the Synthesis of 3,4-Bis(4-nitrofurazan-3-yl)furoxanOrganic Process Research and Development38 dayssaveRefWorksSFX Info
[ASAP] Flow Toolkit for Measuring Reaction Enthalpy and Application to Highly Exothermic Synthesis of AlkylaluminoxanesOrganic Process Research and Development39 dayssaveRefWorksSFX Info
[ASAP] Driving Aspirational Process Mass Intensity Using Simple Structure-Based PredictionOrganic Process Research and Development39 dayssaveRefWorksSFX Info
[ASAP] Efficient Synthesis of (<italic toggle="yes">S</italic>)‑1-Boc-3-aminopiperidine in a Continuous Flow System Using ω‑Transaminase-Immobilized Amino-Ethylenediamine-Modified Epoxide SupportsOrganic Process Research and Development42 dayssaveRefWorksSFX Info
[ASAP] Application of the Polonovski Reaction: Scale-up of an Efficient and Environmentally Benign Opioid DemethylationOrganic Process Research and Development44 dayssaveRefWorksSFX Info
[ASAP] Scaling up a C–H Borylation: Addressing the Safety Concerns of an Iridium-Catalyzed Process for Multikilo Scale ManufactureOrganic Process Research and Development49 dayssaveRefWorksSFX Info
[ASAP] Development of an Improved Synthetic Process of Clonazepam by Preventing the Formation of a Trimeric Compound in the Presence of HClOrganic Process Research and Development51 dayssaveRefWorksSFX Info
[ASAP] Some Items of Interest to Process R&D Chemists and EngineersOrganic Process Research and Development52 dayssaveRefWorksSFX Info
[ASAP] Determination of Purge Factors for Use in Oligonucleotide Control StrategiesOrganic Process Research and Development58 dayssaveRefWorksSFX Info
[ASAP] High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from <sc>l</sc>‑Phenylalanine via Linear and Divergent Enzymatic CascadesOrganic Process Research and Development60 dayssaveRefWorksSFX Info
[ASAP] Comparison of One-Dimensional and Two-Dimensional Population Balance Models for Optimization of a Crystallization Process for a Needle-Shaped Active Pharmaceutical IngredientOrganic Process Research and Development61 dayssaveRefWorksSFX Info
[ASAP] High Yielding Continuous-Flow Synthesis of NorketamineOrganic Process Research and Development62 dayssaveRefWorksSFX Info
[ASAP] Synthesis Optimization, Scale-Up, and Catalyst Screening Efforts toward the MGAT2 Clinical Candidate, BMS-963272Organic Process Research and Development64 dayssaveRefWorksSFX Info
[ASAP] Scale-Up of Diazonium Salts and Azides in a Three-Step Continuous Flow SequenceOrganic Process Research and Development66 dayssaveRefWorksSFX Info
[ASAP] Reaction of Irbesartan with Nitrous Acid Produces Irbesartan Oxime Derivatives, rather than <italic toggle="yes">N</italic>‑NitrosoirbesartanOrganic Process Research and Development67 dayssaveRefWorksSFX Info
[ASAP] Recent Advances in Enzyme Immobilization Utilizing Nanotechnology for BiocatalysisOrganic Process Research and Development72 dayssaveRefWorksSFX Info
[ASAP] Efficient Divergent Synthesis of 2′‑<italic toggle="yes">O</italic>,4′‑<italic toggle="yes">C</italic>‑Ethylene-Bridged Nucleic Acid (ENA) PhosphoramiditesOrganic Process Research and Development73 dayssaveRefWorksSFX Info
[ASAP] Enzymatic Cascade in a Simultaneous, One-Pot Approach with <italic toggle="yes">In Situ</italic> Product Separation for the Asymmetric Production of (4<italic toggle="yes">S</italic>,5<italic toggle="yes">S</itOrganic Process Research and Development74 dayssaveRefWorksSFX Info
[ASAP] Development of a Scalable Route to a Pyrrolidone Compound via a HydroxyfuranoneOrganic Process Research and Development74 dayssaveRefWorksSFX Info
[ASAP] Real-Time and In Situ Monitoring of Transmetalation of Grignard with Manganese(II) Chloride by Raman SpectroscopyOrganic Process Research and Development79 dayssaveRefWorksSFX Info
[ASAP] Some Items of Interest to Process R&D Chemists and EngineersOrganic Process Research and Development79 dayssaveRefWorksSFX Info
[ASAP] Regulatory HighlightsOrganic Process Research and Development79 dayssaveRefWorksSFX Info
[ASAP] Impact of Phosphine Featurization Methods in Process DevelopmentOrganic Process Research and Development79 dayssaveRefWorksSFX Info
[ASAP] Modeling and Experimental Validation of Continuous Biocatalytic Oxidation in Two Continuous Stirred Tank Reactors in SeriesOrganic Process Research and Development79 dayssaveRefWorksSFX Info
[ASAP] Development and Process Intensification of an Efficient Flow–Cascade Reaction Sequence in the Synthesis of AfizagabarOrganic Process Research and Development81 dayssaveRefWorksSFX Info
[ASAP] Stereoselective Nickel(II)-Catalyzed Addition of Aryl Grignards to Diphenylacetylene in the Synthesis of ZuclomipheneOrganic Process Research and Development87 dayssaveRefWorksSFX Info
[ASAP] Stereoselective Synthesis of a Tubulysin Core for Antibody–Drug Conjugate StudiesOrganic Process Research and Development88 dayssaveRefWorksSFX Info
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