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Brain endothelial cell TRPA1 channels initiate neurovascular coupling

DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

To choose or not to choose

Integron activity accelerates the evolution of antibiotic resistance

TRex, a fast multi-animal tracking system with markerless identification, and 2D estimation of posture and visual fields

MetaHiC phage-bacteria infection network reveals active cycling phages of the healthy human gut

Open science takes on Parkinson's disease

A multifaceted analysis reveals two distinct phases of chloroplast biogenesis during de-etiolation in <em>Arabidopsis</em>

Identification of host proteins differentially associated with HIV-1 RNA splice variants

The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function

A Non-stop identity complex (NIC) supervises enterocyte identity and protects from pre-mature aging

Glycine acylation and trafficking of a new class of bacterial lipoprotein by a composite secretion system

Graphical-model framework for automated annotation of cell identities in dense cellular images

Specialized contributions of mid-tier stages of dorsal and ventral pathways to stereoscopic processing in macaque

Real time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin binding proteins

A nuclease- and bisulfite-based strategy captures strand-specific R-loops genome-wide

Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization

Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events

Deficient spermiogenesis in mice lacking <em>Rlim</em>

Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation

Physically asymmetric division of the <em>C. elegans</em> zygote ensures invariably successful embryogenesis

Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in <em>Shaker</em> K+ channels

A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch

Three-dimensional reconstruction of a whole insect reveals its phloem sap-sucking mechanism at nano-resolution

COVID-19 CG enables SARS-CoV-2 mutation and lineage tracking by locations and dates of interest

Toxins, mutations and adaptations

Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin

Integration of IL-2 and IL-4 signals coordinates divergent regulatory T cell responses and drives therapeutic efficacy

Identifying molecular features that are associated with biological function of intrinsically disordered protein regions

March Mammal Madness and the power of narrative in science outreach

Evolutionary shifts in taste coding in the fruit pest <em>Drosophila suzukii</em>

Investigation of <em>Drosophila</em> <em>fruitless</em> neurons that express Dpr/DIP cell adhesion molecules

Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs and mRNAs in live bacterial cells

Incomplete removal of extracellular glutamate controls synaptic transmission and integration at a cerebellar synapse

Accelerating with FlyBrainLab the discovery of the functional logic of the <em>Drosophila</em> brain in the connectomic era

Functional reallocation of sensory processing resources caused by long-term neural adaptation to altered optics

Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil

Redox controls RecA protein activity via reversible oxidation of its methionine residues

Molecular structures of the eukaryotic retinal importer ABCA4

A remote sensing derived data set of 100 million individual tree crowns for the National Ecological Observatory Network

LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior

Volatile DMNT directly protects plants against <em>Plutella xylostella</em> by disrupting peritrophic matrix barrier in midgut

Repressing <em>Ago2</em> mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs

High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox

Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses

Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

Medium spiny neurons activity reveals the discrete segregation of mouse dorsal striatum

Control of feeding by Piezo-mediated gut mechanosensation in <em>Drosophila</em>