Terkko Navigator / Clinical Epigenetics

Validating biomarkers and models for epigenetic inference of alcohol consumption from blood

Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers

High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments

Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals

Correction to: Chromatin insulation dynamics in glioblastoma: challenges and future perspectives of precision oncology

Guidelines for pre-analytical conditions for assessing the methylation of circulating cell-free DNA

SETD2-mediated epigenetic regulation of noncanonical Wnt5A during osteoclastogenesis

Association of peripheral blood DNA methylation level with Alzheimer’s disease progression

DNA methylation-based profiling reveals distinct clusters with survival heterogeneity in high-grade serous ovarian cancer

Distinguishable DNA methylation defines disease susceptibility influenced by race and ethnicity

Race/ethnicity-associated blood DNA methylation differences between Japanese and European American women: an exploratory study

Epigenetic targeting of the ACE2 and NRP1 viral receptors limits SARS-CoV-2 infectivity

DNA methylation signatures of incident coronary heart disease: findings from epigenome-wide association studies

Diagnosis of pulmonary nodules by DNA methylation analysis in bronchoalveolar lavage fluids

DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

Investigating the DNA methylation profile of e-cigarette use

Histone H3 lysine 27 acetylation profile undergoes two global shifts in undernourished children and suggests altered one-carbon metabolism

Combined effects of progesterone and SOCS3 DNA methylation on T2DM: a case–control study

Prenatal and postnatal traffic pollution exposure, DNA methylation in Shank3 and MeCP2 promoter regions, H3K4me3 and H3K27me3 and sociability in rats’ offspring

Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers

Correction to: Evaluation of global and intragenic hypomethylation in colorectal adenomas improves patient stratification and colorectal cancer risk prediction

Impact of vitamin C supplementation on placental DNA methylation changes related to maternal smoking: association with gene expression and respiratory outcomes

DNA 5-hydroxymethylcytosine in pediatric central nervous system tumors may impact tumor classification and is a positive prognostic marker

Hi-C profiling of cancer spheroids identifies 3D-growth-specific chromatin interactions in breast cancer endocrine resistance

Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma

METTL3-dependent MALAT1 delocalization drives c-Myc induction in thymic epithelial tumors

Impact of molecular surgical margin analysis on the prediction of pancreatic cancer recurrences after pancreaticoduodenectomy

Prenatal risk factors and neonatal DNA methylation in very preterm infants

Cellular reprogramming and epigenetic rejuvenation

Dynamics of epigenetic regulator gene BCOR mutation and response predictive value for hypomethylating agents in patients with myelodysplastic syndrome

Longitudinal analysis of individual cfDNA methylome patterns in metastatic prostate cancer

Transcriptional epigenetic regulation of Fkbp1/Pax9 genes is associated with impaired sensitivity to platinum treatment in ovarian cancer

DNA methyltransferase inhibitors combination therapy for the treatment of solid tumor: mechanism and clinical application

Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation

Pre-implantation alcohol exposure induces lasting sex-specific DNA methylation programming errors in the developing forebrain

Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging

Identifying causal models between genetically regulated methylation patterns and gene expression in healthy colon tissue

DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque

Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes

DNA methylation patterns at and beyond the histological margin of early-stage invasive lung adenocarcinoma radiologically manifested as pure ground-glass opacity

Patients with PWS and related syndromes display differentially methylated regions involved in neurodevelopmental and nutritional trajectory

A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease

Childhood-onset dystonia-causing KMT2B variants result in a distinctive genomic hypermethylation profile

PRC2: an epigenetic multiprotein complex with a key role in the development of rhabdomyosarcoma carcinogenesis

Childhood growth and development and DNA methylation age in mid-life

Evaluation of global and intragenic hypomethylation in colorectal adenomas improves patient stratification and colorectal cancer risk prediction

Differential DNA methylation and changing cell-type proportions as fibrotic stage progresses in NAFLD

Correction to: Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers

Chromatin insulation dynamics in glioblastoma: challenges and future perspectives of precision oncology

Interplay of Val66Met and BDNF methylation: effect on reward learning and cognitive performance in major depression