Terkko Navigator / Clinical Epigenetics

DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas

DNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs

Early-life exposure to severe famine is associated with higher methylation level in the IGF2 gene and higher total cholesterol in late adulthood: the Genomic Research of the Chinese Famine (GRECF) study

Smoking-associated AHRR demethylation in cord blood DNA: impact of CD235a+ nucleated red blood cells

Detection of HPV RNA molecules in stratified mucin-producing intraepithelial lesion (SMILE) with concurrent cervical intraepithelial lesion: a case report

Porcine parvovirus VP1/VP2 on a time series epitope mapping: exploring the effects of high hydrostatic pressure on the immune recognition of antigens

High sustained virologic response rates of sofosbuvir-based regimens in Chinese patients with HCV genotype 3a infection in a real-world setting

The interaction of hepatitis B virus with the ubiquitin proteasome system in viral replication and associated pathogenesis

Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China

Dynamics of gene regulatory networks and their dependence on network topology and quantitative parameters– the case of phage λ

Pairwise efficiency: a new mathematical approach to qPCR data analysis increases the precision of the calibration curve assay

Is automatic detection of hidden knowledge an anomaly?

Computational determination of hERG-related cardiotoxicity of drug candidates

Conventionally used reference genes are not outstanding for normalization of gene expression in human cancer research

Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

Batch correction evaluation framework using a-priori gene-gene associations: applied to the GTEx dataset

Capturing the differences between humoral immunity in the normal and tumor environments from repertoire-seq of B-cell receptors using supervised machine learning

Comparison of kNN and k-means optimization methods of reference set selection for improved CNV callers performance

Rare variant phasing using paired tumor:normal sequence data

NeoPredPipe: high-throughput neoantigen prediction and recognition potential pipeline

Promoter methylation changes and vascular dysfunction in pre-eclamptic umbilical vein

Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus

Prenatal epigenetics diets play protective roles against environmental pollution

Epigenetics in cancer therapy and nanomedicine

DNA methylation changes related to nutritional deprivation: a genome-wide analysis of population and in vitro data

Circadian rhythms in the three-dimensional genome: implications of chromatin interactions for cyclic transcription

Functional roles of lncRNAs and its potential mechanisms in neuropathic pain

Prognostic implications and interaction of L1 methylation and p53 expression statuses in advanced gastric cancer

Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas

Circulating cell-free DNA use for diagnosing cholangiocarcinoma

ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort

Prenatal adverse environment is associated with epigenetic age deceleration at birth and hypomethylation at the hypoxia-responsive EP300 gene

Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure

Epigenetic silencing of miR-340-5p in multiple myeloma: mechanisms and prognostic impact

UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells

Methylation at cg05575921 of a smoking-related gene (AHRR) in non-smoking Taiwanese adults residing in areas with different PM2.5 concentrations

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer

Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk

Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine

Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome

Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

DNA methylome profiling of granulosa cells reveals altered methylation in genes regulating vital ovarian functions in polycystic ovary syndrome

Novel parent-of-origin-specific differentially methylated loci on chromosome 16

Promoter methylation of ADAMTS1 and BNC1 as potential biomarkers for early detection of pancreatic cancer in blood

Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets

Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study

Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood