Table of Contents

Chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals / Riccardo A.A. Muzzarelli.
Physical properties of chitosan and derivatives in sol and gel states / Marguerite Rinaudo.
Absorption promotion properties of chitosan and derivatives / Akira Yamamoto.
Biocompatibility and biodegradation of chitosan and derivatives / Ahmad Sukari Halim ... [et al.].
Biological and pharmacological activity of chitosan and derivatives / Teresa Cunha ... [et al.].
Biological, chemical, and physical compatibility of chitosan and biopharmaceuticals / Masayuki Ishihara ... [et al.].
Approaches for functional modification or crosslinking of chitosan / A. Anitha ... [et al.].
Use of chitosan and derivatives in conventional biopharmaceutical dosage forms formulation / Teófilo Vasconcelos, Pedro Barrocas, Rui Cerdeira.
Manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals / Franca Ferrari ... [et al.].
Chitosan and derivatives for biopharmaceutical use : mucoadhesive properties / Katharina Leithner, Andreas Bernkop-Schnürch.
Chitosan-based systems for mucosal delivery of biopharmaceuticals / Sonia Al-Qadi, Ana Grenha, Carmen Remuñán-López.
Chitosan-based delivery systems for mucosal vaccination / Gerrit Borchard, Farnaz Esmaeili, Simon Heuking.
Chitosan-based nanoparticulates for oral delivery of biopharmaceuticals / Filipa Antunes, Fernanda Andrade, Bruno Sarmento.
Chitosan-based systems for ocular delivery of biopharmaceuticals / Suresh P. Vyas, Rishi Paliwal, Shivani Rai Paliwal.
Chemical modification of chitosan for delivery of DNA and SIRNA / You-Kyoung Kim ... [et al.].
Target-specific chitosan-based nanoparticle systems for nucleic acid delivery / Shardool Jain, Mansoor Amiji.
Functional PEGylated chitosan systems for biopharmaceuticals / Hee-Jeong Cho ... [et al.].
Stimuli-sensitive chitosan-based systems for biopharmaceuticals / Cuiping Zhai, Jinfang Yuan, Qingyu Gao.
Chitosan copolymers for biopharmaceuticals / Ramon Novoa-Carballal, Ricardo Riguera, Eduardo Fernandez-Megia.
Application of chitosan for anti-cancer biopharmaceutical delivery / Claudia Philippi ... [et al.].
Chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine / Tao Jiang ... [et al.].
Wound healing properties of chitosan and its use in wound dressing biopharmaceuticals / Tyler G. St. Denis ... [et al.].
Toxicological properties of chitosan and derivatives for biopharmaceutical applications / Thomas J. Kean, Maya Thanou.
Regulatory status of chitosan and derivatives / Michael Dornish, David S. Kaplan, Sambasiva R. Arepalli.
Patentability and intellectual property issues related with chitosan-based biopharmaceutical products / Mafalda Videira, Rogrio Gaspar.
Quality control and good manufacturing practice (GMP) for chitosan-based biopharmaceutical products / Torsten Richter, Maika Gulich, Katja Richter.
Preclinical and clinical use of chitosan and derivatives for biopharmaceuticals : from preclinical research to the bedside / David A. Zaharoff ... [et al.]. Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules - making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential.
Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules - making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential.
Neves, José das;Sarmento, Bruno
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John Wiley & Sons
2012
9781119962960
9780470978320
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