Table of Contents

Historical Overview of Chemical Carcinogenesis.
Multistage Carcinogenesis.
Tobacco Smoke Carcinogens and Lung Cancer.
Mechanisms of Estrogen Carcinogenesis: Modulation by Botanical Natural Products.
Heterocyclic Aromatic Amines: Potential Human Carcinogens.
Aflatoxin and Hepatocellular Carcinoma.
Metabolic Activation of Chemical Carcinogens.
Detoxication of Chemical Carcinogens and Chemoprevention.
Covalent Polycyclic Aromatic Hydrocarbon-DNA Adducts: Carcinogenicity, Structure, and Function --Oxidation and Deamination of DNA by Endogenous Sources.
Lipid Peroxide-DNA Adducts.
Chemical Carcinogenesis and Epigenetics.
Nucleotide Excision Repair from Bacteria to Humans: Structure-Function Studies.
Base-Excision Repair: Role of DNA Polymerase ß in Late-Stage Base Excision Repair.
O⁶-Alkylguanine-DNA Alkyltransferase.
Bypass DNA Polymerases.
Mutagenesis: The Outcome of Faulty Replication of DNA.
p53 and Ras Mutations in Cancer and Experimental Carcinogenesis.