Terkko Navigator / Cellular immunology

Galectin-9 as a biomarker of disease severity.

Comparing thermal stress reduction strategies that influence MDSC accumulation in tumor bearing mice.

Reactive myelopoiesis and the onset of myeloid-mediated immune suppression: Implications for adoptive cell therapy.

Differential signaling patterns of stimulated bone marrow-derived dendritic cells underα1-antitrypsin-enriched conditions.

Causal link between immunoglobulin G glycosylation and cancer: A potential glycobiomarker for early tumor detection.

Sex differences in M2 polarization, chemokine and IL-4 receptors in monocytes and macrophages from asthmatics.

Stem cell-like memory T cells: A perspective from the dark side.

Activated mesangial cells acquire the function of antigen presentation.

Functional responses of resident human T cells in intact liver tissue.

Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly.

The LUBAC participates in lysophosphatidic acid-induced NF-κB activation.

Engagement of CD45 alters early signaling events in human T cells co-stimulated through TCR + CD28.

The roles of tumor-associated macrophages in tumor angiogenesis and metastasis.

NK cells modulate T cell responses via interaction with dendritic cells in Chlamydophila pneumoniae infection.

Overexpression of early T cell differentiation-specific transcription factors transforms the terminally differentiated effector T cells into less differentiated state.

B cell depletion in murine lupus using cytotoxic T lymphocytes in vivo: Feasibility and benefit.

TAK1 lessens the activity of the paracaspase MALT1 during T cell receptor signaling.

Cytokine stimulation of the choriocarcinoma cell line JEG-3 leads to alterations in the HLA-G expression profile.

An accumulation of two populations of dendritic cells in skin-draining lymph nodes in response to the expression of thymic stromal lymphopoietin in the skin.

IL-1β enhances human placenta-derived mesenchymal stromal cells ability to mediate Th1/Th2 and Th1/CD4+IL-10+ T cell balance and regulates its adhesion, proliferation and migration via PD-L1.

Combined antitumor effects of anti-EGFR variant III CAR-T cell therapy and PD-1 checkpoint blockade on glioblastoma in mouse model.

Essential role for Cmtm7 in cell-surface phenotype, BCR signaling, survival and Igμ repertoire of splenic B-1a cells.

Early recruited neutrophils promote asthmatic inflammation exacerbation by release of neutrophil elastase.

IL-33 induced airways inflammation is partially dependent on IL-9.

Autophagy efficacy and vitamin D status: Population effects.

HMGB1-induced ILC2s activate dendritic cells by producing IL-9 in asthmatic mouse model.

Pulmonary inflammatory response to influenza virus infection in pigs is regulated by DAP12 and macrophage M1 and M2 phenotypes.

NK cells prevent T cell lymphoma development in T cell receptor-transgenic mice.

Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1+T cells.

Regulatory B cells in infection, inflammation, and autoimmunity.

B7-H3: A promising therapeutic target for autoimmune diseases.

Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis.

Usefulness of IL-21, IL-7, and IL-15 conditioned media for expansion of antigen-specific CD8+ T cells from healthy donor-PBMCs suitable for immunotherapy.

Deep sequencing reveals the skewed B-cell receptor repertoire in plaques and the association between pathogens and atherosclerosis.

Effects of vitamin D on macrophages and myeloid-derived suppressor cells (MDSCs) hyperinflammatory response in the lungs of COVID-19 patients.

MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment.

Molecular cargo in myeloid-derived suppressor cells and their exosomes.

Identification of H7N9 hemagglutinin novel protein epitopes that elicit strong antibody-dependent, cell-mediated cytotoxic activities with protection from influenza infection in mouse model.

Novel T regulatory cells come of age: The curious incident of a mouse in Tennessee, delayed thymectomy and chimeric receptors!

IL-6 as a major regulator of MDSC activity and possible target for cancer immunotherapy.

Role of orally induced regulatory T cells in immunotherapy and tolerance.

Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy.

Programmed T cell differentiation: Implications for transplantation.

CD4+ T cell phenotypes in the pathogenesis of immune thrombocytopenia.

Generation and functional assessment of nonhuman primate regulatory dendritic cells and their therapeutic efficacy in renal transplantation.

Recent advances into the role of pattern recognition receptors in transplantation.

Exploiting immunometabolism and T cell function for solid organ transplantation.

Microbiota in organ transplantation: An immunological and therapeutic conundrum?

Curdlan stimulates tissue mast cells to synthesize pro-inflammatory mediators, generate ROS, and migrate via Dectin-1 receptor.

Inclusion of Dap10 or 4-1BB costimulation domains in the chPD1 receptor enhances anti-tumor efficacy of T cells in murine models of lymphoma and melanoma.