Terkko Navigator / Cell Host and Microbe

Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen

CRISPR-Cas System of a Prevalent Human Gut Bacterium Reveals Hyper-targeting against Phages in a Human Virome Catalog

Recruitment of Adult Precursor Cells Underlies Limited Repair of the Infected Larval Midgut in Drosophila

Bioengineered Human Organ-on-Chip Reveals Intestinal Microenvironment and Mechanical Forces Impacting Shigella Infection

HIV Rebound Is Predominantly Fueled by Genetically Identical Viral Expansions from Diverse Reservoirs

Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features

Structural Basis for Tetherin Antagonism as a Barrier to Zoonotic Lentiviral Transmission

A Delicate Balance between Bacterial Iron and Reactive Oxygen Species Supports Optimal C. elegans Development

Redondoviridae, a Family of Small, Circular DNA Viruses of the Human Oro-Respiratory Tract Associated with Periodontitis and Critical Illness

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

The Landscape of Genetic Content in the Gut and Oral Human Microbiome

Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition

Commensal Neisseria Kill Neisseria gonorrhoeae through a DNA-Dependent Mechanism

Mapping Interactions of Microbial Metabolites with Human G-Protein-Coupled Receptors

Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila

Meta-Analysis Reveals Reproducible Gut Microbiome Alterations in Response to a High-Fat Diet

A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection

A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity

A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability

Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity

Dynamic Modulation of the Gut Microbiota and Metabolome by Bacteriophages in a Mouse Model

IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins

Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

Bacterial Factors Required for Transmission of Streptococcus pneumoniae in Mammalian Hosts

Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope

Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin

Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1

Intestinal Bile Acids Induce a Morphotype Switch in Vancomycin-Resistant Enterococcus that Facilitates Intestinal Colonization

Adaptive Evolution within Gut Microbiomes of Healthy People

Strain- and Species-Level Variation in the Microbiome of Diabetic Wounds Is Associated with Clinical Outcomes and Therapeutic Efficacy

Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis

Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

Plasmacytoid Dendritic Cells and Infected Cells Form an Interferogenic Synapse Required for Antiviral Responses

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection

Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion

Complement C4 Prevents Viral Infection through Capsid Inactivation

Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut

Cleaved Cochlin Sequesters Pseudomonas aeruginosa and Activates Innate Immunity in the Inner Ear

Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria

Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance

NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25

Malassezia Is Associated with Crohn’s Disease and Exacerbates Colitis in Mouse Models

Polyamines: Small Molecules with a Big Role in Promoting Virus Infection

Flexible Use of Nuclear Import Pathways by HIV-1

Making Sense of Antisense in Antibiotic Drug Discovery

Fly Antiviral RNA Silencing and miRNA Biogenesis Claim ARS2

The Tangled Web of Signaling in Innate Immunity