Terkko Navigator / Cell Death & Disease

Tenascin-cmediated vasculogenic mimicry formation via regulation of MMP2/MMP9 in glioma

The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation

RUNX1 contributes to the mesenchymal subtype of glioblastoma in a TGFβ pathway-dependent manner

Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Upregulation of IGF2R evades lysosomal dysfunction-induced apoptosis of cervical cancer cells via transport of cathepsins

Airway epithelial regeneration requires autophagy and glucose metabolism

Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway

HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression

FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival

Neurons can upregulate Cav-1 to increase intake of endothelial cells-derived extracellular vesicles that attenuate apoptosis via miR-1290

Browning of white adipose tissue after a burn injury promotes hepatic steatosis and dysfunction

Modulation of autophagy by RTN-1C: role in autophagosome biogenesis

Cisplatin exposure causes c-Myc-dependent resistance to CDK4/6 inhibition in HPV-negative head and neck squamous cell carcinoma

Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function

Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons

POTEE drives colorectal cancer development via regulating SPHK1/p65 signaling

Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6

A role for spinal cord hypoxia in neurodegeneration

Current translational potential and underlying molecular mechanisms of necroptosis

A split-GFP tool reveals differences in the sub-mitochondrial distribution of wt and mutant alpha-synuclein

Correction: miR-29a contributes to breast cancer cells epithelial–mesenchymal transition, migration, and invasion via downregulating histone H4K20 trimethylation through directly targeting SUV420H2

Long noncoding RNA LINC00518 acts as a competing endogenous RNA to promote the metastasis of malignant melanoma via miR-204-5p/AP1S2 axis

Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway

Hepatocyte-derived exosomal MiR-194 activates PMVECs and promotes angiogenesis in hepatopulmonary syndrome

Inhibition of STAT3 in tubular epithelial cells prevents kidney fibrosis and nephropathy in STZ-induced diabetic mice

FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia

Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer

p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway

PITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progression

RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity

MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer

miR-223 overexpression inhibits doxorubicin-induced autophagy by targeting FOXO3a and reverses chemoresistance in hepatocellular carcinoma cells

A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence

Ablation of RIP3 protects from dopaminergic neurodegeneration in experimental Parkinson’s disease

Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice

Activation of Piezo1 sensitizes cells to TRAIL-mediated apoptosis through mitochondrial outer membrane permeability

RBBP6, a RING finger-domain E3 ubiquitin ligase, induces epithelial–mesenchymal transition and promotes metastasis of colorectal cancer

The paracrine induction of prostate cancer progression by caveolin-1

ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

Correction: X-chromosome-linked miR548am-5p is a key regulator of sex disparity in the susceptibility to mitochondria-mediated apoptosis

GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer

LncRNA RPPH1 promotes colorectal cancer metastasis by interacting with TUBB3 and by promoting exosomes-mediated macrophage M2 polarization

CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells

Correction: MAG induces apoptosis in cerebellar granule neurons through p75NTR demarcating granule layer/white matter boundary

Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system

Correction: TLR4 signaling drives mesenchymal stromal cells commitment to promote tumor microenvironment transformation in multiple myeloma

Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells

Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway