Terkko Navigator / Cancer Letters

The meiosis-specific cohesin component stromal antigen 3 promotes cell migration and chemotherapeutic resistance in colorectal cancer

CAMK2N1 suppresses hepatoma growth through inhibiting E2F1-mediated cell-cycle signaling

A Novel cytarabine analog evokes synthetic lethality by targeting MK2 in p53-deficient cancer cells

Angiogenic factor AGGF1 acts as a tumor suppressor by modulating p53 post-transcriptional modifications and stability via MDM2

HPV-induced Nurr1 promotes cancer aggressiveness, self-renewal, and radioresistance via ERK and AKT signaling in cervical cancer

Targeting neutrophil extracellular traps with thrombomodulin prevents pancreatic cancer metastasis

Non-coding RNA in thyroid cancer - Functions and mechanisms

Palmitic acid negatively regulates tumor suppressor PTEN through T366 phosphorylation and protein degradation

Splicing factor SF3B1 is overexpressed and implicated in the aggressiveness and survival of hepatocellular carcinoma

Her4 promotes cancer metabolic reprogramming via the c-Myc-dependent signaling axis

CircARHGAP12 promotes nasopharyngeal carcinoma migration and invasion via ezrin-mediated cytoskeletal remodeling

RNA binding proteins: Linking mechanotransduction and tumor metastasis

Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope

The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours

Cedrol suppresses glioblastoma progression by triggering DNA damage and blocking nuclear translocation of the androgen receptor

Elevated GCN5 expression confers tamoxifen resistance by upregulating AIB1 expression in ER-positive breast cancer

Combined blockade of polo-like kinase and pan-RAF is effective against NRAS-mutant non-small cell lung cancer cells

Antitumor efficacy of oncolytic HSV-1 expressing cytosine deaminase is synergistically enhanced by DPD down-regulation and EMT inhibition in uveal melanoma xenograft

Pancreatic adenocarcinoma preferentially takes up and is suppressed by synthetic nanoparticles carrying apolipoprotein A-II and a lipid gemcitabine prodrug in mice

Orally available tubulin inhibitor VERU-111 enhances antitumor efficacy in paclitaxel-resistant lung cancer

Beta2 glycoprotein I-derived therapeutic peptides induce sFlt-1 secretion to reduce melanoma vascularity and growth

Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect

A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity

Extracellular RNA: Emerging roles in cancer cell communication and biomarkers

Loss of histone lysine methyltransferase EZH2 confers resistance to tyrosine kinase inhibitors in non-small cell lung cancer

The microRNA-424/503 cluster: A master regulator of tumorigenesis and tumor progression with paradoxical roles in cancer

The epigenetic roles of DNA N6-Methyladenine (6mA) modification in eukaryotes

ADAM28: Another ambivalent protease in cancer

Corrigendum to “FAT1 prevents epithelial mesenchymal transition (EMT) via MAPK/ERK signaling pathway in esophageal squamous cell cancer” [Canc. Lett. 397 (2017) 83–93]

TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends

Hypoxia-driven intratumor heterogeneity and immune evasion

CAR T-cell therapy for triple-negative breast cancer: Where we are

Exosomes in head and neck cancer: Roles, mechanisms and applications

Comment on ‘Clinical significance and inflammatory landscapes of a novel recurrence associated immune signature in early-stage lung adenocarcinoma’

Targeting the radiation-induced TR4 nuclear receptor-mediated QKI/circZEB1/miR-141-3p/ZEB1 signaling increases prostate cancer radiosensitivity

UDP-glucose 6-dehydrogenase knockout impairs migration and decreases in vivo metastatic ability of breast cancer cells

Reactivation of BMP signaling by suboptimal concentrations of MEK inhibitor and FK506 reduces organ-specific breast cancer metastasis

Response to comment on ‘clinical significance and inflammatory landscapes of a novel recurrence-associated immune signature in early-stage lung adenocarcinoma’

Angiotensin II type 1 receptor blocker telmisartan inhibits the development of transient hypoxia and improves tumour response to radiation

miR-204/COX5A axis contributes to invasion and chemotherapy resistance in estrogen receptor-positive breast cancers

Immunogenic chemotherapy effectively inhibits KRAS-Driven lung cancer

Neutrophils: Accomplices in metastasis

Corrigendum to“PDL1-targeted vaccine exhibits potent antitumor activity by simultaneously blocking PD1/PDL1 pathway and activating PDL1-specific immune responsesˮ [Canc. Lett. 476 (2020) 170–182]

Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model

Silencing of miR490–3p by H. pylori activates DARPP-32 and induces resistance to gefitinib

Differential mutation spectrum and immune landscape in African Americans versus whites: A possible determinant to health disparity in head and neck cancer

Platelet factor 4 regulates T cell effector functions in malignant pleural effusions

Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes

Non-coding RNAs in gastric cancer

Sterol synthesis pathway inhibition as a target for cancer treatment