Table of Contents

Cover; Half-title; Title; Copyright; Contents; Contributors; Acknowledgements and Disclosures; Introduction: revision of an old transmitter; Part I The neurobiology of norepinephrine; 1 Neuroanatomical and chemical organization of the locus coeruleus; 2 Interactions of norepinephrine with other neurotransmitter systems: anatomical basis and pharmacology; 3 Receptors for norepinephrine and signal transduction pathways; 4 Regulation of gene transcription in the central nervous system by norepinephrine; 5 The norepinephrine transporter and regulation of synaptic transmission. Recent discoveries about norepinephrine's contribution to health, disease, and therapy make this synthesis of historical and recent information very timely.