Terkko Navigator / Bioquicknews.com

Oxygen-Sensing Mechanism Based on Small RNA (sRNA) Is Key to E. coli Locating Region of Colon in Which to Set Up Most Threatening Infections; Discovery May Ultimately Enable Avoidance of These Food-Borne Infections

From the Tiny Testes of Flies, Rockefeller Scientists Derive Insights into How New Genes Arise

FDA Approves New Drug (Pretomanid) for Treatment-Resistant Forms of Tuberculosis That Affects the Lungs; Approval Signals FDA’s Continued Focus on Facilitating Development of New Treatments to Fight Antimicrobial-Resistant Infections

First-Ever in Vitro Culture Method for Monkey Malaria Parasite Should Allow Rapid, High-Throughput Testing of Possible Drugs for Relapsing Malaria in Humans & Endangered Penguins

Study Identifies Gene Mutation (in RABL3 Gene) Linked to Hereditary Pancreatic Cancer

Variants in MS4A4A Gene Influence Levels of Soluble TREM2 and Affect Susceptibility to Alzheimer’s Disease; Results Suggest Increased Focus on Brain’s Immune Cells (Microglia)

Lost in Translation: Researchers Discover Surprising Amount of Variation In tRNA Genes; Suggest Possible Role in Disease

Researchers ID Possible Target Matrix Protein (Perlecan) in Effort to Halt Spread of Pancreatic Cancer

Enterovirus Antibodies Detected in CSF of Acute Flaccid Myelitis (AFM) Patients; New Study Adds to Knowledge About Rare Condition

Long-Term, Anti-Rejection-Drug-Free Tolearance of Pancreas Islets Cells Induced by Apoptotic Donor Leukocytes in Non-Human Primates; Anti-Rejection Drugs Completely Discontinued 21 Days After Transplant

Self-Sterilizing Polymer Proves Effective Against Drug-Resistant Pathogens

Discovery of Maturation Plasticity in Acute Myeloid Leukemia Cells May Redirect Research

TB Mycobacteria Can Use Carbon Monoxide for Survival

Study Reveals Intracellular Release Mechanism for ASCT2-Transportd Nutrient Amino Acid Glutamine; Study May Lay Groundwork for Development of Small Molecules to Inhibit Growth of Cancer Cells

International OCD Foundation (IOCDF) Holds 26th Annual OCD Conference (2019) in Austin, Texas, July 19-21; Over 2,000 Attend from 49 States and 24 Countries

Compound (Resveratrol) Found In Red Wine and Grape & Berry Skins & Seeds May Open Door to New Treatments for Depression & Anxiety; Research Lays Groundwork for Use of Resveratrol in Novel Anti-Depressants

Discovery of Alpha-Synclein DNA Repair Function Could Lead to New Treatments for Parkinson's & Other Brain Diseases

Certain Gut Bacteria (Clostridia) Prevent Obesity in Mice; Population of These Bacteria Influenced by Immune System; Possible Clues to Human Obesity

Bacteria Separated by Billions of Years of Evolution and Employing Different Mechanisms of Photosynthesis Share Common Photosynthetic Sites; Results Suggest New View of Evolution of Photosynthesis

Researchers Uncover New Evidence for Origin of RNA Splicing Within Human Genes; Strongest Evidence to Date That the Spliceosome Evolved from a Bacterial Group II Intron

New CRISPR Platform (RESCUE) Expands RNA Editing Capabilities; Enables Cytosine to Uridine Changes; Zhang Team Shows That Technique Can Be Used to Convert APOE4 Alzheimer’s Risk Variant to APOE2 Non-Risk Variant

Scientists Find New Cause of Cellular Aging--Cells Stop Making Nucleotides--Findings May Have Major Implications for Cancer and Age-Related Conditions

Newly Identified Pluripotent Liver Cell May Ultimately Provide Alternative to Liver Transplants; Single-Cell RNA Sequencing Key to This Major Discovery

Unexpected Developmental Hierarchy Revealed in New Study of Highly Unusual Disease (Langerhans Cell Histiocytosis)--Epigenomics and Single-Cell Sequencing Were Key

CRISPR Activation Screen Identifies Genes That Protect Cells from Zika Virus Infection and Also Prevent Death of Zika-Infected Cells

How Pufferfish Developed Its Unusual Spines

Vitamin D Supplementation May Slow Diabetes Progression, New Study Suggests

Chemists Find Simplest Organic Molecules Can Self-Assemble to Give Cell-Like Structures Under Early Earth Conditions

Molecular Sensor Scouts DNA Damage and Supervises Repair; Xeroderma Pigmentosa Connection

Exosomes May Have“Huge Relevance” to Treating & Diagnosing Developmental Brain Disorders; New Work at Scripps Suggests Cellular Cargo Transporters Play Profound Role in Creating Brain Cells & Circuits

Nunavik Inuit in Canada’s Arctic Are Genetically Unique & Share Variants That May Correlate with Brain Aneurysms, Among Distinct Genetic Signatures In Pathways Involving Lipid Metabolism & Cell Adhesion, Possibly Adaptive to High-Fat Diets &a

New Study Explains Molecular Mechanism for Therapeutic Anti-Convulsive Effects of Cilantro

Diabetes-Associated Heart Failure Risk, High in General, Is Much Higher in Women Than in Men, New Global Study Shows

Scientists ID Cellular Connetion Between Diabetes and Blood Vessel Narrowing; Further Study Could Confirm Molecular Target for Possible Reduction of Blood Vessel Complications of Diabetes

Pioneering Study Shows Decrease in One Type of Dopapime Receptor in Wild Songbirds Under Captivity Stress

NIH Publishes Largest Genomic Study on Type 2 Diabetes In Sub-Saharan African Populations; Researchers Show Critical Association Between Diabetes and Previously Unlinked ZRANB3 Gene

Link Between Increased Expression of AEBP1 Gene and Severe Liver Disease Suggested by Study Results

SIRT6 Over-Expression May Prevent Progression of Diabetes, Study Suggests

Newly Identified Protein (KHNYN) Works with ZAP Protein to Promote Destruction of HIV Virus Containing Clustered CpG Dinucleotides

Two Potentiator Drugs Act on CFTR Protein in Cystic Fibrosis by Holding Hinge Open to Allow Ion Flow; Focus on This Mechanism May Enable Further Progress on Drug Development & Disease Treatment

Scientists Identify an RNA-Binding Protein (SRSF3) As Essential for Correct Heart Contraction & Survival—Capping of Contraction-Related mRNAs Revealed As Key Process Influenced by SRSF3; This Capping Protects Against Development of Systolic Heart

Infection-Fighting Protein (HRI) Also Senses Protein Misfolding In Non-Infected Cells; Finding May Offer Insights into Approaches to Prevent/Treat Neurodegenerative Diseases Like Parkinson’s

First Complete Wiring Diagram of an Animal (C. elegans) Nervous System Established

Triplet-Targeted Therapy Improves Survival for Patients with Advanced Colorectal Cancer and BRAF Mutations; Phase III Trial Results May Change Standard of Care for Up to 15% of Colorectal Cancer Patients

Strain of Oncolytic Common Cold Virus (Coxsackievirus A21) Could Revolutionize Treatment of Bladder Cancer

Tiny Molecular Change Reverses Prediabetes in Mice; Remarkable Results Point to Potential Diabetes Drug Target and Highlight Possible Role for Ceramides in Sensing Nutrition

Scientists Apply Bacterial Homing Capability to Enable Stem Cells to Home to Heart Tissue; Approach Offers“Enormous Potential” for Millions Suffering from Heart Disease Around the Globe

New, Low-Cost OCT Retinal Scanner Could Help Prevent Blindness Worldwide; Duke-Led Effort Creates Portable, Much Cheaper Device Nearly As Accurate As Current Very Costly Standard-of-Care OCT Instruments

Archaeological Mystery Solved with Modern Genetics -- Y Chromosomes Reveal Population Boom and Bust in Ancient Japan

Cancer-Sniffing Dogs 97% Accurate in Identifying Lung Cancer in Blood Serum of Patients Versus Controls