Terkko Navigator / Bioquicknews.com

NK-Cell-Derived Exosomes, Harvested from On‐Chip Biogenesis, Exhibit Antitumor Activity Vs Non-Small-Cell Lung Cancer Cells

LSD May Offer Viable Treatment for Certain Mental Disorders; New Work in Mouse Model Increases Understanding of the Mechanism of Psychelic’s Impact on Brain and Potential for Therapeutic Use

Scientists Discover New Transmission Mechanism (Exosome-Mediated) of Sorafenib Resistance Among Hepatocellular Carcinoma Cells; A Circular RNA (circRNA-SORE) Increases Sorafenib Resistance & Silencing of circRNA-SORE Overcomes This Resistance in

Split Biosciences, Now Parse Biosciences, Announces $7M in Series A Funding to Democratize Single-Cell RNA Sequencing

Tony Fauci Interviewed by Leroy Hood & Presented Luminary Award of Precision Medicine World Conference (PMWC 2021) at Monday’s Opening Day of PMWC 2021 Virtual Meeting (January 25-27)--“21st Century Precision Medicine in the Age of COVID-19”

Study Finds Especially High Rates of Lupus in Certain U.S. Racial/Ethnic Groups: American Indians/Alaska Natives & Black Females

BrainStorm Announces Publication of Preclinical Data Highlighting the Potential of NurOwn®-Derived Exosome-Based Treatment for COVID-19 Acute Respiratory Distress Syndromw (ARDS)

Cryo-Electron Microscopy Study Allows Researchers to Visualize Structural Changes in E. coli Enzyme Synthesizing Ribosomal RNA That Shift It Between Turbo- and Slow-Modes Depending on Bacteria's Growth Rate

Possible Parkinson's Disease Therapeutics (BMP5 & BMP7) Discovered in Alpha-Synuclein Mouse Model

Journal Article Published on Codiak’s Versatile engEx™ Platform for Engineered Exosomes; Publication Details Characterization of Novel Scaffold Proteins That Can Enable Engineered Exosomes with Defined Therapeutic Properties

Sloan Kettering Scientists May Have Solved 100-Year-Old Mystery About Cancer; Warburg Effect (Switch from Aerobic to Anaerobic Glycolysis) Linked with Activity of Powerhouse Enzyme PI3 Kinase

Researchers Develop Mathematical Model to Explain Complex Architecture of Termite Mounds; "Termite Mounds Are Amongst the Greatest Examples of Animal Architecture on Our Planet"

Developmental Origins of Eczema & Psoriasis Discovered; Results Provide Completely New Understanding of Inflammatory Diseases, Open Up New Avenues for Research on Other Inflammatory Diseases Such As Rheumatoid Arthritis & Inflammatory Bowel D

COVID-19 Risk Reduced Up to 80% by Lilly's Neutralizing Monoclonal Antibody Bamlanivimab (LY-Cov555) at Nursing Homes in BLAZE-2 Phase 3 Trial

Intoxicating Chemicals in Catnip and Silver Vine Protect Felines from Mosquito Bites; Results May Provide Clues to Mosquito Repellant for Humans

New Treatment for Central Nervous System Tumors, Such As Glioblastoma, Enters Phase I Clinical Trials; Peptide Immune Checkpoint Ligand from OX2 Therapeutics Is First-of-Its Kind Cancer Treatment

First High-Resolution, Quantitative Tracking of Bacterial Membrane Vesicles (MVs) in Response to Antibiotic Treatment; Results“Will Undoubtedly Open a New Avenue of Research on This Fascinating and Currently Hot Topic"

Butterfly Wing Clap Explains Mystery of Their Fluttery, Apparently Inefficient Flight; Expelled Air from Pocket Between Cupped Wings Acts Like Expelled Air from Jet Engine, Enabling Highly Efficient Flight

Intense Immunosuppression Followed by Hematopoietic Stem Cell Transplant May Provide Long-Term Benefit for People with Multiple Sclerosis

Exosomes & EVs in Infectious Diseases--Virtual Conference Jan 25-28; Registration Ends Thurs Jan 21 11:59 PM

Intranasally Administered Small Peptide That Blocks COVID-19 Spike Protein Interaction with ACE-2 Shows Success in COVID-19 Therapy in Mouse Model

Mental Health Research Funder“1907 Research” Announces Three Recipients of Its Inaugural 1907 Trailblazer Award; $120,000 Two-Year Grants to Support Pioneering, Early-Career Mental Health Researchers: Benjamin Bartelle, Laura Lewis, & Katherine S

Remarkable Results: UCSF Case Study of Personalized Electro-Stimulation of Select Brain Regions for Treatment of Severe Depression Suggests That“Even the Most Severe Depression Is a Brain-Circuit Disease” That Can Be Nudged Back into a Healthy State

Once-in-a-Lifetime Event: Free Virtual Precision Medicine World Conference (PMWC 2021) (January 25-27) on COVID-19 Pandemic Will Feature 50 World-Class Speakers, Including Anthony Fauci & Leroy Hood; Free Registration Ends January 22

Diet High In Omega-3 Fatty Acids Helps Arctic Ground Squirrels Stay Warmer During Hibernation and Also Increases Their Amounts of Brown Fat

Exosomes from Diabetics Contain Higher Levels of miR-20b-5p and Suppress Wound Healing, As Does miR-20b-5p Alone; Exosomes Loaded with miR-20b-5p Inhibitors May Accelerate Wound Healing in Diabetics, Author Suggest

Innocan Pharma Successfully Completes Large-Scale Production of Exosomes

Possible Breakthrough in Producing Large Quantities of Potential Therapeutic Drug Compound (FR) Originally Found in Bacterium Colonizing Coralberry Plant; Compound Inhibits Gq Proteins and Has Shown Suggestive Effectiveness in Asthma and Certain Canc

How Plants Produce Defensive Toxins Without Harming Themselves; Researchers Elucidate Biosynthesis & Mode of Action of Diterpene Glycosides in Wild Tobacco

Cancer Research Reveals How Mutations in a Specific Gene (RUNX1) Cause Different Types Of Cancers

Researchers Reveal Mechanism That May Underlie Irritable Bowel Syndrome

Scientists Find Antibody That Blocks Dengue Virus in Mouse Model

Scientists Discover“Spectacular” Bat from West Africa

CRSPR/Cas9 Gene-Editing Produces Tenfold Increase in Superbug-Slaying Antibiotics (Formicamycins) Found in Bacteria Living in Nests of a Certain African Ant (Tetraponera penzigi)

Breakthrough Against Antibiotic-Resistance of World’ Leading Superbug Actinobacter baumannii Achieved Using Bacteriophage in Mouse Model

Enhanced Oral Administration of Exosomes with Milk Protein Casein Shows Possible Effectiveness in Treating Muscular Dystrophy and Heart Failure in Mouse Model

Severe Sepsis May Be Predicted by Detected Release of Common Protein (Galectin-1), UConn-Led Study Suggests

Focused Ultrasound Shows Promise for Parkinson's Disease; NEJM Article Reports

Entirety of Colon Cancer Cells, Not Just Subsets, Can Coordinately Adopt Evolutionarily Conserved Embryonic Survival Program to Slow Growth & Conserve Energy Under Stress of Chemotherapy; Autophagy Inhibitor Can Disrupt This Cancer Survival Strat

Exosomes & Laser for Acne Scars--BENEV Announces Investigative Report on Combination Treatment with Human Adipose Tissue Stem Cell-Derived Exosomes and Fractional CO2 Laser for Acne Scars

University of Minnesota Begins Phase I First-in-Human Clinical Trial for Glioblastoma; Novel Immune-Directed Approach, Advanced by Work on Glioblastomas Developing Naturally in Dogs, Could Be“Landmark Breakthrough” in Treatment of Rapidly Fatal Disea

Groundbreaking Trial for Treatment of Severe COVID-19 Shows Success Using Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs)

Glioblastoma Could Be Linked to Combination of Mutational Change in Key Cells and Healing Process After Brain Injury, New Study Suggests; Findings May Lay Foundation for Precision Medicine Efforts to Treat Deadly Disease

Brown Fat May Protect Against Numerous Chronic Diseases, Rockefeller Study of 50,000 People Suggests; May Also Hold Clues to New Obesity Treatments

DNA from Seabiscuit’s Hooves Offer Clues to Famous Race Horse’s Gifts of Speed & Stamina

Adaptation of Forward Genetics Technique Leads to ID of Gene (KDM5A) Newly Associated with Autism Spectrum Disorder (ASD); Approach May Open Door to ID of More ASD-Associated Mutations and Advance Future Treatments; Article Co-Author Is Nobelist

Nanoparticle Drug-Delivery System Developed to Aid Treatment of Brain Disorders/Diseases; Use in Mouse Models Results In Unprecedented Penetration of siRNA Across Intact Blood-Brain Barrier; System Could Be“Game-Changer” in Treatment of CNS Diseases

Traditional Medicines Used in Ghana Show Promise Against Tropical Diseases, Including Schistosomiasis, River Blindness, and Elephantiasis

New Virtual Screening Strategy Identifies Existing Lymphoma Drug (Pralatrexate) That Inhibits SARS-CoV-2 Virus Replication; Drug Targets Viral RNA-Dependent RNA Polymerase (RdRP); Viral Inhibition Is Stronger Than That Achieved by Remdesivir

Article Reporting Anecdotal Success of CytoDyn’s Leronlimab (Vyrologix™) in Treatment of Critically Ill COVID-19 Patients Accepted for Journal Publication; Four Patients, Initially on Mechanical Ventilators, Fully Recover After Leronlimab Treatment