Terkko Navigator / Biophysical Chemistry

Membrane shape as determinant of protein properties

Matairesinol, an active constituent of HC9 polyherbal formulation, exhibits HDAC8 inhibitory and anticancer activity

The interplay between Glucocerebrosidase,α-synuclein and lipids in human models of Parkinson's disease

The structural reconformation of peptides in enhancing functional and therapeutic properties: Insights into their solid state crystallizations

Energy absorption of human red blood cells and conductivity of the cytoplasm influenced by temperature

Coupling mechanisms in ATP synthesis: Rejoinder to "Response to molecular-level understanding of biological energy coupling and transduction"

Bioinformatics analysis and biochemical characterisation of ABC transporter-associated periplasmic substrate-binding proteins ModA and MetQ from Helicobacter pylori strain SS1

A theoretical study on the effects of interdomain flexibility on drug encounter rate for coronavirus nucleocapsid-type proteins

Structural preferences of an anti-fouling peptide: From single chain to small molecular assemblies

HIV-1 genomic RNA U3 region forms a stable quadruplex-hairpin structure

Editorial for the special issue "Protein misfolding and amyloid aggregation" of Biophysical Chemistry

Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods

Salt dependent mesoscopic model for RNA at multiple strand concentrations

Characterisation of the structural, dynamic and aggregation properties of the W64R amyloidogenic variant of human lysozyme

Dengue fusion peptide in Langmuir monolayers: A binding parameter study

Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2

Effects of pH on an IDP conformational ensemble explored by molecular dynamics simulation

Thermodynamics of amyloid fibril formation from non-equilibrium experiments of growth and dissociation

Native disulphide-linked dimers facilitate amyloid fibril formation by bovine milkα_S2-casein

The role of surfaces on amyloid formation

Transformation of matter in living organisms during growth and evolution

Molecular dynamics simulations reveal the destabilization mechanism of Alzheimer's disease-related tau R3-R4 Protofilament by norepinephrine

Clues to the non-carcinogenicity of certain N-Nitroso compounds: Role of alkylated DNA bases

A common ATP-dependent stepping model for kinesin-5 and kinesin-1: Mechanism of bi-directionality of kinesin-5

A lowly populated, transientβ-sheet structure in monomeric Aβ^1-42 identified by multinuclear NMR of chemical denaturation

Multi-step molecular docking and dynamics simulation-based screening of large antiviral specific chemical libraries for identification of Nipah virus glycoprotein inhibitors

Recent trends in analytical and digital techniques for the detection of the SARS-Cov-2

Raman spectral imaging of ¹³C²H¹⁵N-labeledα-synuclein amyloid fibrils in cells

Proposal of novel inhibitors for vitamin-D receptor: Molecular docking, molecular mechanics and ab initio molecular orbital simulations

Structure of the microbial carboxypeptidase T complexed with the transition state analog N-sulfamoyl-l-lysine

Computational modelling of potentβ-secretase (BACE1) inhibitors towards Alzheimer's disease treatment

Viper toxins affect membrane characteristics of human erythrocytes

Expression, purification and characterisation of large quantities of recombinant human IAPP for mechanistic studies

Phytochemical profile, antioxidant,α-amylase inhibition, binding interaction and docking studies of Justicia carnea bioactive compounds with α-amylase

Effects of free soluble iron on thermal aggregation of hemoglobin

Marshall's nucleic acid: From double-helical structure to a potent intercalator

Synthesis and in vitro quantification of amyloid fibrils by barbituric and thiobarbituric acid-based chromene derivatives

Modulation of membrane physical properties by natural insecticidal ketones

Herpes simplex virus encoded ICP6 protein forms functional amyloid assemblies with necroptosis-associated host proteins

Elastic compliance and adsorption profiles of Bovine serum albumin at fluid/solid interface in the presence of electrolytes

The role of water in the primary nucleation of protein amyloid aggregation

Discrete-state stochastic kinetic models for target DNA search by proteins: Theory and experimental applications

β-Turn exchanges in the α-synuclein segment 44-TKEG-47 reveal high sequence fidelity requirements of amyloid fibril elongation

A biophysical toolset to probe the microscopic processes underlying protein aggregation and its inhibition by molecular chaperones

Response to "Molecular-level understanding of biological energy coupling and transduction: Response to "Chemiosmotic misunderstandings""

Stabilization of a potential anticancer thiosemicarbazone derivative in Sudlow site I of human serum albumin: In vitro spectroscopy coupled with molecular dynamics simulation

An insight into the interaction betweenα-ketoamide- based inhibitor and coronavirus main protease: A detailed in silico study

Biophysical processes underlying cross-seeding in amyloid aggregation and implications in amyloid pathology

Exploring the polymorphism, conformational dynamics and function of amyloidogenic peptides and proteins by temperature and pressure modulation

Visualizing and trapping transient oligomers in amyloid assembly pathways