Terkko Navigator / Biomedicine & pharmacotherapy

Circular RNAs in depression: Biogenesis, function, expression, and therapeutic potential

Gemigliptin suppresses salivary dysfunction in streptozotocin-induced diabetic rats

The new coumarin compound Bis 3 ameliorates cognitive disorder and suppresses brain-intestine-liver systematic oxidative stress in high-fat diet mice

Environmental contaminant BPA causes intestinal damage by disrupting cellular repair and injury homeostasis in vivo and in vitro

The emerging role of non-coding RNAs in the regulation of PI3K/AKT pathway in the carcinogenesis process

Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation

Resveratrol supplementation and acute pancreatitis: A comprehensive review

5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition

Human endeavor for anti-SARS-CoV-2 pharmacotherapy: A major strategy to fight the pandemic

Nanotechnology shaping stem cell therapy: Recent advances, application, challenges, and future outlook

Ozone inhalation induces exacerbation of eosinophilic airway inflammation and Th2-skew immune response in a rat model of AR

Overexpression of human ATP-binding cassette transporter ABCG2 contributes to reducing the cytotoxicity of GSK1070916 in cancer cells

Copper nanoparticles: Biosynthesis, characterization, and protoscolicidal effects alone and combined with albendazole against hydatid cyst protoscoleces

Deoxidized gulose moiety attenuates the pulmonary toxicity of 6'-deoxy-bleomycin Z without effect on its antitumor activity

Muscone derivative ZM-32 inhibits breast tumor angiogenesis by suppressing HuR-mediated VEGF and MMP9 expression

Ivabradine prevents deleterious effects of dopamine therapy in heart failure: No role for HCN4 overexpression

Low-dose PPI to prevent bleeding after ESD: A multicenter randomized controlled study

Embryo-toxicity of docosahexaenoic and eicosapentaenoic acids: In vivo and in silico investigations using the chick embryo model

The influence of melatonin on the heart rhythm – An in vitro simulation with murine embryonic stem cell derived cardiomyocytes

Lung cancer chemotherapy using nanoparticles: Enhanced target ability of redox-responsive and pH-sensitive cisplatin prodrug and paclitaxel

Curcumin and cardiovascular diseases: Focus on cellular targets and cascades

LncRNA influence sequential steps of hepatocellular carcinoma metastasis

Persistent long-term platelet activation and endothelial perturbation in women with Takotsubo syndrome

Anti-nociceptive effects of Sedum Lineare Thunb. on spared nerve injury-induced neuropathic pain by inhibiting TLR4/NF-κB signaling in the spinal cord in rats

Drug-drug interactions between salvianolate injection and aspirin based on their metabolic enzymes

d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway

Effect of atorvastatin versus rosuvastatin on inflammatory biomarkers and LV function in type 2 diabetic patients with dyslipidemia

Novel bioactive properties of low-polarity fractions from sea-buckthorn extracts (Elaeagnus rhamnoides (L.) A. Nelson) – (in vitro)

Foeniculum vulgare seed extract induces apoptosis in lung cancer cells partly through the down-regulation of Bcl-2

Optimization of culture medium for Sanghuangporus vaninii and a study on its therapeutic effects on gout

Novel N,N-di-alkylnaphthoimidazolium derivative of β-lapachone impaired Trypanosoma cruzi mitochondrial electron transport system

Babao Dan improves neurocognitive function by inhibiting inflammation in clinical minimal hepatic encephalopathy

Mycophenolate mediated remodeling of gut microbiota and improvement of gut-brain axis in spontaneously hypertensive rats

PSB 603 – a known selective adenosine A2B receptor antagonist – has anti-inflammatory activity in mice

Improvements in estrogen deficiency-induced hypercholesterolemia by Hypericum perforatum L. extract are associated with gut microbiota and related metabolites in ovariectomized (OVX) rats

Processed meat products with added plant antioxidants affect the microbiota and immune response in C57BL/6JRj mice with cyclically induced chronic inflammation

Alpiniae oxyphyllae Fructus and Alzheimer’s disease: An update and current perspective on this traditional Chinese medicine

The role of heat shock proteins in the regulation of fibrotic diseases

Imaging genomics for accurate diagnosis and treatment of tumors: A cutting edge overview

4-Aminoquinoline compounds from the Spanish flu to COVID-19

Alternative methods of photodynamic therapy and oxygen consumption measurements—A review

Efficacy of nanoemulsion with Pterodon emarginatus Vogel oleoresin for topical treatment of cutaneous leishmaniasis

Antileishmanial activity of fullerol and its liposomal formulation in experimental models of visceral leishmaniasis

Mechanistic insights into the intracellular release of doxorubicin from pH-sensitive liposomes

Lipid-based nanocarriers co-loaded with artemether and triglycerides of docosahexaenoic acid: Effects on human breast cancer cells

Could natural products modulate early inflammatory responses, preventing acute respiratory distress syndrome in COVID-19-confirmed patients?

Mechanisms underlie the proconvulsant effects of sildenafil

Berberine in the treatment of ulcerative colitis: A possible pathway through Tuft cells

Oncopreventive effects of theanine and theobromine on dimethylhydrazine-induced colon cancer model

In-silico driven design and development of spirobenzimidazo-quinazolines as potential DNA gyrase inhibitors