Table of Contents

Principles of cell and membrane function.
Homeostasis : volume and composition of body fluid compartments.
Signal transduction, membrane receptors, second messengers, and regulation of gene expression.
The nervous system : introduction to cells and systems.
Generation and conduction of action potentials.
Synaptic transmission.
The somatosensory system.
The special senses.
Organization of motor function.
Integrative functions of the nervous system.
The autonomic nervous system and its central control.
Skeletal muscle physiology.
Cardiac muscle.
Smooth muscle.
Overview of circulation.
Elements of cardiac function.
Properties of the vasculature.
Regulation of the heart and vasculature.
Integrated control of the cardiovascular system.
Introduction to the respiratory system.
Static lung and chest wall mechanics.
Dynamic lung and chest wall mechanics.
Ventilation, perfusion, and ventilation/perfusion relationships.
Oxygen and carbon dioxide transport.
Control of respiration.
Nonphysiological functions of the lung : host defense and metabolism.
Functional anatomy and general principles of regulation in the gastrointestinal tract.
The cephalic, oral, and esophageal phases of the integrated response to a meal.
The gastric phase of the integrated response to a meal.
The small intestinal phase of the integrated response to a meal.
The colonic phase of the integrated response to a meal.
Transport and metabolic functions of the liver.
Elements of renal function.
Solute and water transport along the nephron : tubular function.
Control of body fluid osmolality and volume.
Potassium, calcium, and phosphate homeostasis.
Role of the kidneys in the regulation of acid-base balance.
Introduction to the endocrine system.
Hormonal regulation of energy metabolism.
Hormonal regulation of calcium and phosphate metabolism.
The hypothalamus and pituitary gland.
The thyroid gland.
The adrenal gland.
The male and female reproductive systems.